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Found 108 of ph data with Target = 'Calpain-1 catalytic subunit'
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University Of Tennessee Health Science Center

LigandPNGBDBM23865(3-[(2S)-2-[1-(9H-fluoren-9-yl)acetamido]-4-methylp...)
Affinity DataKi:  8nM ΔG°:  -45.7kJ/molepH: 7.4 T: 2°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University Of Tennessee Health Science Center

LigandPNGBDBM23866(MDL28170 | Z-Val-Phe-CHO | benzyl N-[(1S)-2-methyl...)
Affinity DataKi:  10nM ΔG°:  -45.2kJ/molepH: 7.4 T: 2°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University Of Tennessee Health Science Center

LigandPNGBDBM23859(3-[(2S)-2-[1-(adamantan-1-yl)acetamido]-4-methylpe...)
Affinity DataKi:  41nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University Of Tennessee Health Science Center

LigandPNGBDBM23857(3-[(2S)-2-(3-cyclohexylpropanamido)-4-methylpentan...)
Affinity DataKi:  50nM ΔG°:  -41.3kJ/molepH: 7.4 T: 2°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University Of Tennessee Health Science Center

LigandPNGBDBM23863(3-[(2S)-2-(3,3-diphenylpropanamido)-4-methylpentan...)
Affinity DataKi:  63nM ΔG°:  -40.7kJ/molepH: 7.4 T: 2°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University Of Tennessee Health Science Center

LigandPNGBDBM23861(3-[(2S)-2-(1,1-diphenylacetamido)-4-methylpentanam...)
Affinity DataKi:  108nM ΔG°:  -39.4kJ/molepH: 7.4 T: 2°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University Of Tennessee Health Science Center

LigandPNGBDBM23858(Peptidyl alpha-Ketoester, 1b | methyl 3-[(2S)-2-[1...)
Affinity DataKi:  450nM ΔG°:  -35.9kJ/molepH: 7.4 T: 2°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University Of Tennessee Health Science Center

LigandPNGBDBM23860(Peptidyl alpha-Ketoester, 1c | methyl 3-[(2S)-2-(1...)
Affinity DataKi:  944nM ΔG°:  -34.0kJ/molepH: 7.4 T: 2°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University Of Tennessee Health Science Center

LigandPNGBDBM23855(Peptidyl alpha-Ketoester, 1a | methyl 3-[(2S)-2-(3...)
Affinity DataKi:  1.05E+3nM ΔG°:  -33.8kJ/molepH: 7.4 T: 2°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University Of Tennessee Health Science Center

LigandPNGBDBM23864(Peptidyl alpha-Ketoester, 1e | methyl 3-[(2S)-2-[1...)
Affinity DataKi:  1.20E+3nM ΔG°:  -33.5kJ/molepH: 7.4 T: 2°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University Of Tennessee Health Science Center

LigandPNGBDBM23862(Peptidyl alpha-Ketoester, 1d | methyl 3-[(2S)-2-(3...)
Affinity DataKi:  2.15E+3nM ΔG°:  -32.0kJ/molepH: 7.4 T: 2°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University Of Tennessee Health Science Center

LigandPNGBDBM240262(US9403843, 33)
Affinity DataKi:  2.60E+3nM ΔG°:  -32.4kJ/molepH: 7.6 T: 2°CAssay Description:Full length porcine calpain (156 nM), or papain (236 pM) was added to a solution of 100 mM NaCl, 50 mM HEPES, pH 7.6, 1 mM TCEP, 30 μM Suc-LLVY-AM...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University Of Tennessee Health Science Center

LigandPNGBDBM50437948(CHEMBL2408899 | US9403843, 50)
Affinity DataKi:  2.90E+3nM ΔG°:  -32.1kJ/molepH: 7.6 T: 2°CAssay Description:Full length porcine calpain (156 nM), or papain (236 pM) was added to a solution of 100 mM NaCl, 50 mM HEPES, pH 7.6, 1 mM TCEP, 30 μM Suc-LLVY-AM...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University Of Tennessee Health Science Center

LigandPNGBDBM50437949(CHEMBL2408918 | US9403843, 34)
Affinity DataKi:  3.50E+3nM ΔG°:  -31.7kJ/molepH: 7.6 T: 2°CAssay Description:Full length porcine calpain (156 nM), or papain (236 pM) was added to a solution of 100 mM NaCl, 50 mM HEPES, pH 7.6, 1 mM TCEP, 30 μM Suc-LLVY-AM...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University Of Tennessee Health Science Center

LigandPNGBDBM240232(US9403843, E64)
Affinity DataKi:  4.00E+3nM ΔG°:  -31.3kJ/molepH: 7.6 T: 2°CAssay Description:Full length porcine calpain (156 nM), or papain (236 pM) was added to a solution of 100 mM NaCl, 50 mM HEPES, pH 7.6, 1 mM TCEP, 30 μM Suc-LLVY-AM...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University Of Tennessee Health Science Center

LigandPNGBDBM50437951(CHEMBL2408922 | US9403843, 24a)
Affinity DataKi:  6.00E+3nM ΔG°:  -30.3kJ/molepH: 7.6 T: 2°CAssay Description:Full length porcine calpain (156 nM), or papain (236 pM) was added to a solution of 100 mM NaCl, 50 mM HEPES, pH 7.6, 1 mM TCEP, 30 μM Suc-LLVY-AM...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York

US Patent
LigandPNGBDBM240264(US9403843, 86)
Affinity DataIC50:  30nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York

US Patent
LigandPNGBDBM50437951(CHEMBL2408922 | US9403843, 24a)
Affinity DataIC50:  30nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York

US Patent
LigandPNGBDBM240272(US9403843, 55)
Affinity DataIC50:  40nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York

US Patent
LigandPNGBDBM50437951(CHEMBL2408922 | US9403843, 24a)
Affinity DataIC50:  50nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York

US Patent
LigandPNGBDBM240265(US9403843, 87)
Affinity DataIC50:  50nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York

US Patent
LigandPNGBDBM240251(US9403843, 23a | US9403843, 23b)
Affinity DataIC50:  50nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York

US Patent
LigandPNGBDBM240255(US9403843, 22)
Affinity DataIC50:  100nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York

US Patent
LigandPNGBDBM240249(US9403843, 30a)
Affinity DataIC50:  100nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York

US Patent
LigandPNGBDBM23866(MDL28170 | Z-Val-Phe-CHO | benzyl N-[(1S)-2-methyl...)
Affinity DataIC50:  100nMpH: 7.5 T: 2°CAssay Description:Inhibition of µ-calpain was assayed in the reaction buffer (50 mM Tris-HCl, 50 mM NaCl, 1 mM EDTA, 1 mM EGTA and 5 mM β-mercaptoethanol, pH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York

US Patent
LigandPNGBDBM240232(US9403843, E64)
Affinity DataIC50:  100nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York

US Patent
LigandPNGBDBM50437948(CHEMBL2408899 | US9403843, 50)
Affinity DataIC50:  100nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York

US Patent
LigandPNGBDBM50437949(CHEMBL2408918 | US9403843, 34)
Affinity DataIC50:  100nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York

US Patent
LigandPNGBDBM240233(US9403843, 27)
Affinity DataIC50:  100nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York

US Patent
LigandPNGBDBM240231(US9403843, 26)
Affinity DataIC50:  100nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York

US Patent
LigandPNGBDBM240238(US9403843, 25)
Affinity DataIC50:  100nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York

US Patent
LigandPNGBDBM240262(US9403843, 33)
Affinity DataIC50:  100nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York

US Patent
LigandPNGBDBM240243(US9403843, 68)
Affinity DataIC50:  100nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York

US Patent
LigandPNGBDBM240251(US9403843, 23a | US9403843, 23b)
Affinity DataIC50:  100nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York

US Patent
LigandPNGBDBM50437948(CHEMBL2408899 | US9403843, 50)
Affinity DataIC50:  125nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York

US Patent
LigandPNGBDBM240233(US9403843, 27)
Affinity DataIC50:  150nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York

US Patent
LigandPNGBDBM240242(US9403843, 67)
Affinity DataIC50:  150nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York

US Patent
LigandPNGBDBM240238(US9403843, 25)
Affinity DataIC50:  150nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York

US Patent
LigandPNGBDBM240231(US9403843, 26)
Affinity DataIC50:  150nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Ovis aries (sheep))
University Of Canterbury

LigandPNGBDBM25893((2S)-2-[(5-formyl-1-methyl-1H-pyrrol-2-yl)formamid...)
Affinity DataIC50:  150nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York

US Patent
LigandPNGBDBM62323(US9403843, 24b)
Affinity DataIC50:  175nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York

US Patent
LigandPNGBDBM240247(US9403843, 72)
Affinity DataIC50:  200nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York

US Patent
LigandPNGBDBM240259(US9403843, 36)
Affinity DataIC50:  225nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York

US Patent
LigandPNGBDBM50437951(CHEMBL2408922 | US9403843, 24a)
Affinity DataIC50:  250nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York

US Patent
LigandPNGBDBM240266(US9403843, 88)
Affinity DataIC50:  275nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Ovis aries (sheep))
University Of Canterbury

LigandPNGBDBM25895(N-heterocyclic dipeptide aldehyde, 13 | methyl 5-{...)
Affinity DataIC50:  290nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Ovis aries (sheep))
University Of Canterbury

LigandPNGBDBM25891((2S)-2-[(5-formyl-1H-pyrrol-2-yl)formamido]-3-meth...)
Affinity DataIC50:  290nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York

US Patent
LigandPNGBDBM240273(US9403843, 56)
Affinity DataIC50:  300nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Ovis aries (sheep))
University Of Canterbury

LigandPNGBDBM25894((2S)-3-methyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-2...)
Affinity DataIC50:  340nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees Of Columbia University In The City Of New York

US Patent
LigandPNGBDBM110185(Z-FF-FMK | benzyl N-[1-[(4-fluoro-3-oxo-1-phenylbu...)
Affinity DataIC50:  397nMpH: 7.5 T: 2°CAssay Description:Inhibition of µ-calpain was assayed in the reaction buffer (50 mM Tris-HCl, 50 mM NaCl, 1 mM EDTA, 1 mM EGTA and 5 mM β-mercaptoethanol, pH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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