Compile Data Set for Download or QSAR
Report error Found 153 of ph data with Target = 'Carbonic anhydrase 12'
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 82103BDBM82103(Investigational agent, 4)
Affinity DataKi:  0.900nM ΔG°:  -50.8kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50210256BDBM50210256(CHEMBL26300 | Topiramate, 3 | Sulfamic acid (3aS,5...)
Affinity DataKi:  3.80nM ΔG°:  -47.3kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 82104BDBM82104(Investigational agent, 5)
Affinity DataKi:  4.70nM ΔG°:  -46.7kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  5.70nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase XII by spectrophotometry at pH 7.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  5.70nM ΔG°:  -43.7kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  5.70nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins at pH 7.5 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 150256BDBM150256(US8980932, 4c (DH305))
Affinity DataKi:  6.70nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
US Patent

TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50429915BDBM50429915(CHEMBL2333403)
Affinity DataKd:  6.70nMpH: 7.0Assay Description:Binding affinity to human recombinant CA12 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 150252BDBM150252(US8980932, 6d (DH308))
Affinity DataKi:  7.60nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
US Patent

TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 150250BDBM150250(US8980932, 6b (DH309))
Affinity DataKi:  7.70nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
US Patent

TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 150254BDBM150254(US8980932, 4d (DH302))
Affinity DataKi:  8nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
US Patent

TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 150249BDBM150249(US8980932, 6a (DH307))
Affinity DataKi:  8nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
US Patent

TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 150255BDBM150255(US8980932, 4b (DH304))
Affinity DataKi:  8.10nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
US Patent

TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 150248BDBM150248(US8980932, 7 (DH348))
Affinity DataKi:  8.10nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
US Patent

TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 150251BDBM150251(US8980932, 6c (DH310))
Affinity DataKi:  8.5nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
US Patent

TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50352645BDBM50352645(CHEMBL1822701)
Affinity DataKi:  8.60nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins at pH 7.5 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 150247BDBM150247(US8980932, 9 (DH338))
Affinity DataKi:  8.90nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
US Patent

TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50352643BDBM50352643(CHEMBL1822699)
Affinity DataKi:  9.10nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins at pH 7.5 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50352644BDBM50352644(CHEMBL1822700)
Affinity DataKi:  10.5nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins at pH 7.5 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50429907BDBM50429907(CHEMBL2333397)
Affinity DataKd:  17nMpH: 7.0Assay Description:Binding affinity to human recombinant CA12 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50429917BDBM50429917(CHEMBL2333816)
Affinity DataKd:  17nMpH: 7.0Assay Description:Binding affinity to human recombinant CA12 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50429918BDBM50429918(CHEMBL2333815)
Affinity DataKd:  20nMpH: 7.0Assay Description:Binding affinity to human recombinant CA12 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50352646BDBM50352646(CHEMBL1822702)
Affinity DataKi:  25.3nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins at pH 7.5 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 10882BDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKd:  36nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 10882BDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataKd:  36nMpH: 7.0Assay Description:Binding affinity to human recombinant CA12 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50429922BDBM50429922(CHEMBL2333418 | carbonic anhydrase (CA) inhibitors...)
Affinity DataKd:  40nMpH: 7.0Assay Description:Binding affinity to human recombinant CA12 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50380144BDBM50380144(CHEMBL2010994 | carbonic anhydrase (CA) inhibitors...)
Affinity DataKd:  44nMpH: 8.0Assay Description:Binding affinity to human recombinant CA12 catalytic domain assessed as dissociation constant calculated from kinetic parameters at pH 8 by surface p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50429921BDBM50429921(CHEMBL2333419)
Affinity DataKd:  50nMpH: 7.0Assay Description:Binding affinity to human recombinant CA12 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 10883BDBM10883(Dichlorophenamide, DCP | CHEMBL17 | Sulfonamide, 4...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50429916BDBM50429916(CHEMBL2333402)
Affinity DataKd:  50nMpH: 7.0Assay Description:Binding affinity to human recombinant CA12 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 26999BDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  56nM ΔG°:  -40.7kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 246561BDBM246561(2-Chloro-4-[(2-propyl-1H-benzimidazol-1-yl)acetyl]...)
Affinity DataKd:  62.5nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 150253BDBM150253(US8980932, 4a (DH296))
Affinity DataKi:  64nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
US Patent

TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 246573BDBM246573(2-Chloro-4-{[2-(methylthio)-1H-benzimidazol-1-yl]a...)
Affinity DataKd:  66.7nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 246558BDBM246558(2-Chloro-4-[(2-ethyl-1H-benzimidazol-1-yl)acetyl]b...)
Affinity DataKd:  66.7nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50429911BDBM50429911(CHEMBL2333407)
Affinity DataKd:  77nMpH: 7.0Assay Description:Binding affinity to human recombinant CA12 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50380144BDBM50380144(CHEMBL2010994 | carbonic anhydrase (CA) inhibitors...)
Affinity DataKd:  82nMpH: 8.0Assay Description:Binding affinity to human recombinant CA12 catalytic domain assessed as dissociation constant calculated from saturation signal at pH 8 by surface pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50380148BDBM50380148(CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...)
Affinity DataKd:  90nMpH: 8.0Assay Description:Binding affinity to human recombinant CA12 catalytic domain assessed as dissociation constant calculated from kinetic parameters at pH 8 by surface p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50429920BDBM50429920(CHEMBL2333420)
Affinity DataKd:  91nMpH: 7.0Assay Description:Binding affinity to human recombinant CA12 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50429899BDBM50429899(CHEMBL2333416)
Affinity DataKd:  94nMpH: 7.0Assay Description:Binding affinity to human recombinant CA12 at 37 degC and pH 7.0 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50429909BDBM50429909(CHEMBL2333409)
Affinity DataKd:  100nMpH: 7.0Assay Description:Binding affinity to human recombinant CA12 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50429906BDBM50429906(CHEMBL2333398)
Affinity DataKd:  110nMpH: 7.0Assay Description:Binding affinity to human recombinant CA12 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50429912BDBM50429912(CHEMBL2333406)
Affinity DataKd:  110nMpH: 7.0Assay Description:Binding affinity to human recombinant CA12 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 246564BDBM246564(4-[(2-Butyl-1H-benzimidazol-1-yl)acetyl]-2-chlorob...)
Affinity DataKd:  112nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50163858BDBM50163858(carbonic anhydrase (CA) inhibitors, benzenesulphon...)
Affinity DataKd:  120nMpH: 8.0Assay Description:Binding affinity to human recombinant CA12 catalytic domain assessed as dissociation constant calculated from kinetic parameters at pH 8 by surface p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKd:  133nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKd:  133nMpH: 7.0Assay Description:Binding affinity to human recombinant CA12 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50380148BDBM50380148(CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...)
Affinity DataKd:  140nMpH: 8.0Assay Description:Binding affinity to human recombinant CA12 catalytic domain assessed as dissociation constant calculated from saturation signal at pH 8 by surface pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50429900BDBM50429900(CHEMBL2333417)
Affinity DataKd:  143nMpH: 7.0Assay Description:Binding affinity to human recombinant CA12 at 37 degC and pH 7.0 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50429902BDBM50429902(CHEMBL2333410)
Affinity DataKd:  150nMpH: 7.0Assay Description:Binding affinity to human recombinant CA12 at 37 degC and pH 7.0 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Displayed 1 to 50 (of 153 total ) | Next | Last >>
Jump to: