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Found 78 of ph data with Target = 'Carbonic anhydrase 4'
TargetCarbonic anhydrase 4(Bos taurus (bovine))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM14722(1-N-[5-Sulfamoyl-1,3,4-thiadiazol-2-yl-(aminosulfo...)
Affinity DataKi:  2nM ΔG°:  -48.8kJ/molepH: 7.4 T: 2°CAssay Description:The initial rates of 4-nitrophenylacetate hydrolysis catalysed by different CA isozymes were monitored spectrophotometrically at 400nm with a Cary 3 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM10886(2-N-benzene-1,3,4-thiadiazole-2,5-disulfonamide | ...)
Affinity DataKi:  12nM ΔG°:  -44.5kJ/molepH: 7.4 T: 2°CAssay Description:The initial rates of 4-nitrophenylacetate hydrolysis catalysed by different CA isozymes were monitored spectrophotometrically at 400nm with a Cary 3 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM85658(EZA4)
Affinity DataKi:  13nM ΔG°:  -44.3kJ/molepH: 7.4 T: 2°CAssay Description:The initial rates of 4-nitrophenylacetate hydrolysis catalysed by different CA isozymes were monitored spectrophotometrically at 400nm with a Cary 3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataKi:  24nM ΔG°:  -43.5kJ/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM50141779(2,6-Dimethyl-4-phenyl-1-(4-sulfamoyl-phenyl)-pyrid...)
Affinity DataKi:  29nM ΔG°:  -42.3kJ/molepH: 7.4 T: 2°CAssay Description:The initial rates of 4-nitrophenylacetate hydrolysis catalysed by different CA isozymes were monitored spectrophotometrically at 400nm with a Cary 3 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM82104(Investigational agent, 5)
Affinity DataKi:  30nM ΔG°:  -42.2kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM85563(2-[4-(4-Bromophenylsulfonyl)-Phenyl}-thiazole-4-yl...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition assay using human Carbonic anhydrase I and II and bovine carbonic anhydrase IV. More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM85566(2-[4-(4-Bromophenylsulfonyl)-Phenyl}-thiazole-4-yl...)
Affinity DataKi:  54nM ΔG°:  -41.5kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition assay using human Carbonic anhydrase I and II and bovine carbonic anhydrase IV. More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM82103(Investigational agent, 4)
Affinity DataKi:  56nM ΔG°:  -40.7kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM85562(2-[4-(4-Chlorophenylsulfonyl)-Phenyl}-thiazole-4-y...)
Affinity DataKi:  65nM ΔG°:  -41.0kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition assay using human Carbonic anhydrase I and II and bovine carbonic anhydrase IV. More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM85565(2-[4-(4-Chlorophenylsulfonyl)-Phenyl}-thiazole-4-y...)
Affinity DataKi:  66nM ΔG°:  -41.0kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition assay using human Carbonic anhydrase I and II and bovine carbonic anhydrase IV. More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM33280(CHEMBL153094 | aliphatic sulfamate, 2)
Affinity DataKi:  67.6nM ΔG°:  -40.6kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataKi:  70nM ΔG°:  -40.8kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition assay using human Carbonic anhydrase I and II and bovine carbonic anhydrase IV. More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataKi:  74nM ΔG°:  -40.4kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataKi:  74nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 4 preincubated for 15 mins at pH 7.5 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataKi:  74nM ΔG°:  -40.7kJ/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataKi:  74nM ΔG°:  -37.8kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM33279(CHEMBL24261 | aliphatic sulfamate, 1)
Affinity DataKi:  79.9nM ΔG°:  -40.2kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM85561(2-[4-(Phenylsulfonyl)-Phenyl}-thiazole-4-yl-methyl...)
Affinity DataKi:  83nM ΔG°:  -40.4kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition assay using human Carbonic anhydrase I and II and bovine carbonic anhydrase IV. More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM33281(CHEMBL182455 | bis-sulfamate, 3)
Affinity DataKi:  84.1nM ΔG°:  -40.1kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM85564(2-[4-(Phenylsulfonyl)-Phenyl}-thiazole-4-yl-methyl...)
Affinity DataKi:  87nM ΔG°:  -40.3kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition assay using human Carbonic anhydrase I and II and bovine carbonic anhydrase IV. More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM33282(CHEMBL171476 | bis-sulfamate, 4)
Affinity DataKi:  91.2nM ΔG°:  -39.9kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM26999(4-(1,1-dioxo-1,2-thiazinan-2-yl)benzene-1-sulfonam...)
Affinity DataKi:  95nM ΔG°:  -39.4kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM85659(DCP5)
Affinity DataKi:  120nM ΔG°:  -38.8kJ/molepH: 7.4 T: 2°CAssay Description:The initial rates of 4-nitrophenylacetate hydrolysis catalysed by different CA isozymes were monitored spectrophotometrically at 400nm with a Cary 3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM85660(Sulfonamide, 6)
Affinity DataKi:  170nM ΔG°:  -38.0kJ/molepH: 7.4 T: 2°CAssay Description:The initial rates of 4-nitrophenylacetate hydrolysis catalysed by different CA isozymes were monitored spectrophotometrically at 400nm with a Cary 3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataKi:  220nM ΔG°:  -37.4kJ/molepH: 7.4 T: 2°CAssay Description:The initial rates of 4-nitrophenylacetate hydrolysis catalysed by different CA isozymes were monitored spectrophotometrically at 400nm with a Cary 3 ...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)
Affinity DataKi:  240nM ΔG°:  -37.2kJ/molepH: 7.4 T: 2°CAssay Description:The initial rates of 4-nitrophenylacetate hydrolysis catalysed by different CA isozymes were monitored spectrophotometrically at 400nm with a Cary 3 ...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM26998(6-chloro-3-(dichloromethyl)-1,1-dioxo-3,4-dihydro-...)
Affinity DataKi:  449nM ΔG°:  -35.6kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM248142(Grayanotoxin III (GTX3))
Affinity DataKi:  510nM ΔG°:  -35.9kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataKi:  578nMpH: 7.4Assay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-NPA to 4-nitrophenylate ion over a period of 3 min at 25°C using a spect...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataKi:  580nMpH: 7.4Assay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | CHEMBL1...)
Affinity DataKi:  840nMpH: 7.4Assay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM25896(EMD 486019 | [2-(cycloheptylmethyl)-1,1-dioxo--ben...)
Affinity DataKi:  842nM ΔG°:  -34.7kJ/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM19461(α-CA inhibitor, 5 | 5,7-dihydroxy-2-(4-hydrox...)
Affinity DataKi:  1.12E+3nMpH: 7.4Assay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-NPA to 4-nitrophenylate ion over a period of 3 min at 25°C using a spect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM239159(α-CA inhibitor, 7)
Affinity DataKi:  2.41E+3nMpH: 7.4Assay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-NPA to 4-nitrophenylate ion over a period of 3 min at 25°C using a spect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM239160(α-CA inhibitor, 8)
Affinity DataKi:  2.75E+3nMpH: 7.4Assay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-NPA to 4-nitrophenylate ion over a period of 3 min at 25°C using a spect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM239157(α-CA inhibitor, 2)
Affinity DataKi:  3.76E+3nMpH: 7.4Assay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-NPA to 4-nitrophenylate ion over a period of 3 min at 25°C using a spect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM239161(α-CA inhibitor, 9)
Affinity DataKi:  3.94E+3nMpH: 7.4Assay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-NPA to 4-nitrophenylate ion over a period of 3 min at 25°C using a spect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM23417(α-CA inhibitor, 4 | (-)-Epicatechin | (2R,3R)...)
Affinity DataKi:  3.98E+3nMpH: 7.4Assay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-NPA to 4-nitrophenylate ion over a period of 3 min at 25°C using a spect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM239162(α-CA inhibitor, 10)
Affinity DataKi:  4.36E+3nMpH: 7.4Assay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-NPA to 4-nitrophenylate ion over a period of 3 min at 25°C using a spect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataKi:  4.40E+3nMpH: 7.4Assay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM50210256(CHEMBL26300 | Sulfamic acid (3aS,5aR,8aR,8bS)-2,2,...)
Affinity DataKi:  4.90E+3nM ΔG°:  -29.8kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)
Affinity DataKi:  4.90E+3nM ΔG°:  -30.3kJ/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM23416(α-CA inhibitor, 3 | (+)-Catechin | (2R,3S)-2-...)
Affinity DataKi:  5.60E+3nMpH: 7.4Assay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataKi:  5.64E+3nMpH: 7.4Assay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-NPA to 4-nitrophenylate ion over a period of 3 min at 25°C using a spect...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM50352644(CHEMBL1822700)
Affinity DataKi:  6.74E+3nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 4 preincubated for 15 mins at pH 7.5 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM50352643(CHEMBL1822699)
Affinity DataKi:  7.20E+3nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 4 preincubated for 15 mins at pH 7.5 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM50352645(CHEMBL1822701)
Affinity DataKi:  7.45E+3nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 4 preincubated for 15 mins at pH 7.5 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM50352646(CHEMBL1822702)
Affinity DataKi:  7.50E+3nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 4 preincubated for 15 mins at pH 7.5 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
UniversitÀ Degli Studi Di Firenze

LigandPNGBDBM10884((2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...)
Affinity DataKi:  8.50E+3nM ΔG°:  -28.7kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
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