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Report error Found 107 of ph data with Target = 'Carbonic anhydrase 9'
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 82103BDBM82103(Investigational agent, 4)
Affinity DataKi:  4.90nM ΔG°:  -46.6kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 10888BDBM10888(Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...)
Affinity DataKi:  5.10nM ΔG°:  -46.5kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 150250BDBM150250(US8980932, 6b (DH309))
Affinity DataKi:  7.20nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
US Patent

TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 150249BDBM150249(US8980932, 6a (DH307))
Affinity DataKi:  7.30nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
US Patent

TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 150254BDBM150254(US8980932, 4d (DH302))
Affinity DataKi:  7.30nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
US Patent

TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 150252BDBM150252(US8980932, 6d (DH308))
Affinity DataKi:  7.80nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
US Patent

TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 82104BDBM82104(Investigational agent, 5)
Affinity DataKi:  7.80nM ΔG°:  -45.5kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 150255BDBM150255(US8980932, 4b (DH304))
Affinity DataKi:  7.90nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
US Patent

TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 150256BDBM150256(US8980932, 4c (DH305))
Affinity DataKi:  8nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
US Patent

TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 150247BDBM150247(US8980932, 9 (DH338))
Affinity DataKi:  8.30nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
US Patent

TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 150251BDBM150251(US8980932, 6c (DH310))
Affinity DataKi:  8.30nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
US Patent

TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50352645BDBM50352645(CHEMBL1822701)
Affinity DataKi:  10.2nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 9 preincubated for 15 mins at pH 7.5 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50380144BDBM50380144(CHEMBL2010994 | carbonic anhydrase (CA) inhibitors...)
Affinity DataKd:  13nMpH: 8.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation constant calculated from kinetic parameters at pH 8 by surface pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 11641BDBM11641(1-N-(4-sulfamoylphenyl-ethyl)-2,4,6-trimethylpyrid...)
Affinity DataKi:  14nM ΔG°:  -44.4kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 11640BDBM11640(3-[(2,3,4,5,6-pentafluorophenyl)amino]-1-(4-sulfam...)
Affinity DataKi:  15nM ΔG°:  -44.2kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 11639BDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataKi:  16nM ΔG°:  -44.0kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 11639BDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 16nMpH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 11636BDBM11636(N-[2-(diethylamino)ethyl]-4-[(5-sulfamoyl-1,3,4-th...)
Affinity DataKi:  16nM ΔG°:  -44.0kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 11635BDBM11635(4-sulfamoyl-N-[2-(4-sulfamoylphenyl)ethyl]benzamid...)
Affinity DataKi:  18nM ΔG°:  -43.8kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50352643BDBM50352643(CHEMBL1822699)
Affinity DataKi:  18.5nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 9 preincubated for 15 mins at pH 7.5 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50163859BDBM50163859(carbonic anhydrase (CA) inhibitors, benzenesulphon...)
Affinity DataKd:  19nMpH: 8.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation constant calculated from kinetic parameters at pH 8 by surface pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50352646BDBM50352646(CHEMBL1822702)
Affinity DataKi:  19.4nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 9 preincubated for 15 mins at pH 7.5 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50380144BDBM50380144(CHEMBL2010994 | carbonic anhydrase (CA) inhibitors...)
Affinity DataKd:  20nMpH: 8.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation constant calculated from saturation signal at pH 8 by surface pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 150248BDBM150248(US8980932, 7 (DH348))
Affinity DataKi:  20.4nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
US Patent

TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 103909BDBM103909(JNK3 inhibitor 6 | US8562945, 242)
Affinity DataIC50: 23nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
US Patent

TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 10890BDBM10890(E7070 | Sulfonamide, 7 | Compound 6 | CHEMBL77517 ...)
Affinity DataKi:  24nM ΔG°:  -43.1kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50352644BDBM50352644(CHEMBL1822700)
Affinity DataKi:  24nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 9 preincubated for 15 mins at pH 7.5 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  25nM ΔG°:  -42.7kJ/molepH: 7.4 T: 2°CAssay Description:The initial rates of 4-nitrophenylacetate hydrolysis catalysed by different CA isozymes were monitored spectrophotometrically at 400nm with a Cary 3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  25nM ΔG°:  -40.3kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 10880BDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  25nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 9 preincubated for 15 mins at pH 7.5 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 10881BDBM10881(CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...)
Affinity DataKi:  27nM ΔG°:  -42.5kJ/molepH: 7.4 T: 2°CAssay Description:The initial rates of 4-nitrophenylacetate hydrolysis catalysed by different CA isozymes were monitored spectrophotometrically at 400nm with a Cary 3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 13063BDBM13063(CHEMBL865 | cid_119607 | Bextra | VLX | 4-(5-methy...)
Affinity DataIC50: 27nMpH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 11634BDBM11634(heterocyclic sulfonamide compound 38 | 2,3,4,5,6-p...)
Affinity DataKi:  29nM ΔG°:  -42.6kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 11637BDBM11637((15S)-15-methyl-14-oxotetracyclo[8.7.0.0^{2,7}.0^{...)
Affinity DataKi:  30nM ΔG°:  -42.5kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 11638BDBM11638(N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sul...)
Affinity DataKi:  31nM ΔG°:  -42.4kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 85658BDBM85658(EZA4)
Affinity DataKi:  34nM ΔG°:  -41.9kJ/molepH: 7.4 T: 2°CAssay Description:The initial rates of 4-nitrophenylacetate hydrolysis catalysed by different CA isozymes were monitored spectrophotometrically at 400nm with a Cary 3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50380148BDBM50380148(CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...)
Affinity DataKd:  38nMpH: 8.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation constant calculated from kinetic parameters at pH 8 by surface pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 103908BDBM103908(JNK3 inhibitor 5 | US8562945, 241)
Affinity DataIC50: 40nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
US Patent

TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 103911BDBM103911(JNK3 inhibitor 8 | US8562945, 246)
Affinity DataIC50: 42nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
US Patent

TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 26999BDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  43nM ΔG°:  -41.3kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 10886BDBM10886(BZA1 | CHEMBL73962 | 2-N-benzene-1,3,4-thiadiazole...)
Affinity DataKi:  45nM ΔG°:  -41.2kJ/molepH: 7.4 T: 2°CAssay Description:The initial rates of 4-nitrophenylacetate hydrolysis catalysed by different CA isozymes were monitored spectrophotometrically at 400nm with a Cary 3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50380144BDBM50380144(CHEMBL2010994 | carbonic anhydrase (CA) inhibitors...)
Affinity DataKd:  46nMpH: 7.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation constant calculated from kinetic parameters at pH 7 by surface pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50163859BDBM50163859(carbonic anhydrase (CA) inhibitors, benzenesulphon...)
Affinity DataKd:  46nMpH: 7.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation constant calculated from kinetic parameters at pH 7 by surface pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 85659BDBM85659(DCP5)
Affinity DataKi:  50nM ΔG°:  -41.0kJ/molepH: 7.4 T: 2°CAssay Description:The initial rates of 4-nitrophenylacetate hydrolysis catalysed by different CA isozymes were monitored spectrophotometrically at 400nm with a Cary 3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 10883BDBM10883(Dichlorophenamide, DCP | CHEMBL17 | Sulfonamide, 4...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50380144BDBM50380144(CHEMBL2010994 | carbonic anhydrase (CA) inhibitors...)
Affinity DataKd:  56nMpH: 7.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation constant calculated from saturation signal at pH 7 by surface pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 10887BDBM10887(Sulfamate 7 | [(1R,2S,6S,9R)-4,4,11,11-tetramethyl...)
Affinity DataKi:  58nM ΔG°:  -40.9kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50210256BDBM50210256(CHEMBL26300 | Topiramate, 3 | Sulfamic acid (3aS,5...)
Affinity DataKi:  58nM ΔG°:  -40.6kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 50380148BDBM50380148(CHEMBL2011156 | carbonic anhydrase (CA) inhibitors...)
Affinity DataKd:  62nMpH: 7.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation constant calculated from kinetic parameters at pH 7 by surface pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandChemical structure of BindingDB Monomer ID 150253BDBM150253(US8980932, 4a (DH296))
Affinity DataKi:  70nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
US Patent

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