Compile Data Set for Download or QSAR
Report error Found 17 of ph data with Target = 'Caspase-5'
TargetCaspase-5(Human)
University of Colorado

LigandPNGBDBM223313(Tiaprofenic acid)
Affinity DataIC50: 470nMpH: 7.4Assay Description:Experiments were performed in a 384-well format (Greiner no. 781207) as per the conditions noted here. Caspase-1: 2.5 nM enzyme, 6.5 mM WEHD substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2017
Entry Details Article
PubMed
TargetCaspase-5(Human)
University of Colorado

LigandPNGBDBM50233673(cid_3718 | (+)-2-(4-(1-oxoisoindolin-2-yl)phenyl)p...)
Affinity DataIC50: 590nMpH: 7.4Assay Description:Experiments were performed in a 384-well format (Greiner no. 781207) as per the conditions noted here. Caspase-1: 2.5 nM enzyme, 6.5 mM WEHD substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2017
Entry Details Article
PubMed
TargetCaspase-5(Human)
University of Colorado

LigandPNGBDBM50240374(4-[1,1'-biphenyl-4-yl]-4-oxobutanoic acid | 3-(4-b...)
Affinity DataIC50: 870nMpH: 7.4Assay Description:Experiments were performed in a 384-well format (Greiner no. 781207) as per the conditions noted here. Caspase-1: 2.5 nM enzyme, 6.5 mM WEHD substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2017
Entry Details Article
PubMed
TargetCaspase-5(Human)
University of Colorado

LigandPNGBDBM85511(Toradol | KETOROLAC | CAS_74103-07-4 | Ketorolac t...)
Affinity DataIC50: 1.00E+3nMpH: 7.4Assay Description:Experiments were performed in a 384-well format (Greiner no. 781207) as per the conditions noted here. Caspase-1: 2.5 nM enzyme, 6.5 mM WEHD substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2017
Entry Details Article
PubMed
TargetCaspase-5(Human)
University of Colorado

LigandPNGBDBM223312(Felbinac)
Affinity DataIC50: 2.60E+3nMpH: 7.4Assay Description:Experiments were performed in a 384-well format (Greiner no. 781207) as per the conditions noted here. Caspase-1: 2.5 nM enzyme, 6.5 mM WEHD substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2017
Entry Details Article
PubMed
TargetCaspase-5(Human)
University of Colorado

LigandPNGBDBM50009859((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...)
Affinity DataIC50: 8.10E+3nMpH: 7.4Assay Description:Experiments were performed in a 384-well format (Greiner no. 781207) as per the conditions noted here. Caspase-1: 2.5 nM enzyme, 6.5 mM WEHD substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2017
Entry Details Article
PubMed
TargetCaspase-5(Human)
University of Colorado

LigandPNGBDBM50022271(2-(3-benzoylphenyl)propanoic acid | 2-(3-Benzoylph...)
Affinity DataIC50: 1.00E+4nMpH: 7.4Assay Description:Experiments were performed in a 384-well format (Greiner no. 781207) as per the conditions noted here. Caspase-1: 2.5 nM enzyme, 6.5 mM WEHD substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2017
Entry Details Article
PubMed
TargetCaspase-5(Human)
University of Colorado

LigandPNGBDBM50339185((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | ...)
Affinity DataIC50: 1.10E+4nMpH: 7.4Assay Description:Experiments were performed in a 384-well format (Greiner no. 781207) as per the conditions noted here. Caspase-1: 2.5 nM enzyme, 6.5 mM WEHD substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2017
Entry Details Article
PubMed
TargetCaspase-5(Human)
University of Colorado

LigandPNGBDBM222((S)-5-({5-[1-Carboxymethyl-3-(2-chloro-benzylsulfa...)
Affinity DataKi:  1.10E+4nM ΔG°:  -28.3kJ/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2003
Entry Details Article
PubMed
TargetCaspase-5(Human)
University of Colorado

LigandPNGBDBM220(5-{[(4-{[(2S)-1-carboxy-3-oxopropan-2-yl]carbamoyl...)
Affinity DataKi:  1.20E+4nM ΔG°:  -28.1kJ/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2003
Entry Details Article
PubMed
TargetCaspase-5(Human)
University of Colorado

LigandPNGBDBM221(Pyridine Scaffold 4 | 5-{[(5-{[(2S)-1-carboxy-3-ox...)
Affinity DataKi:  2.20E+4nM ΔG°:  -26.6kJ/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2003
Entry Details Article
PubMed
TargetCaspase-5(Human)
University of Colorado

LigandPNGBDBM224((S)-5-({5-[1-Carboxymethyl-3-(2-chloro-benzylsulfa...)
Affinity DataKi:  2.30E+4nM ΔG°:  -26.5kJ/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2003
Entry Details Article
PubMed
TargetCaspase-5(Human)
University of Colorado

LigandPNGBDBM225(Thiophene Scaffold 66a | (S)-5-5-(1-Carboxymethyl-...)
Affinity DataKi:  2.40E+4nM ΔG°:  -26.4kJ/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2003
Entry Details Article
PubMed
TargetCaspase-5(Human)
University of Colorado

LigandPNGBDBM223(5-{[(5-{[(2S)-1-carboxy-4-{[(2-chlorophenyl)methyl...)
Affinity DataKi:  3.20E+4nM ΔG°:  -25.7kJ/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2003
Entry Details Article
PubMed
TargetCaspase-5(Human)
University of Colorado

LigandPNGBDBM227(Heterocyclic deriv. 69b | (S)-5-({5-[1-Carboxymeth...)
Affinity DataKi:  3.60E+4nM ΔG°:  -25.4kJ/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2003
Entry Details Article
PubMed
TargetCaspase-5(Human)
University of Colorado

LigandPNGBDBM226(Thiophene Scaffold 66b | (S)-5-({5-[1-Carboxymethy...)
Affinity DataKi:  6.30E+4nM ΔG°:  -24.0kJ/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2003
Entry Details Article
PubMed
TargetCaspase-5(Human)
University of Colorado

LigandPNGBDBM219(5-({[(5-{[(2S)-1-carboxy-4-{[(2-chlorophenyl)methy...)
Affinity DataKi:  9.80E+4nM ΔG°:  -22.9kJ/molepH: 7.4 T: 2°CAssay Description:The effectiveness of compounds against the activity of human recombinant caspase-1-8 was measured using fluorometric assays. Assays were carried out ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2003
Entry Details Article
PubMed