Compile Data Set for Download or QSAR
Report error Found 59 of ph data with Target = 'Cytochrome P450 2A6'
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 12341BDBM12341(US8609708, 31 | CHEMBL359657 | US8609708, 1 | CHEM...)
Affinity DataKi:  80nM ΔG°:  -42.1kJ/molepH: 7.5 T: 2°CAssay Description:To measure CYP2A6 activity, coumarin 7-hydroxylation was determined. The formation of the coumarin metabolite, 7-hydroxycoumarin, was determined fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 12345BDBM12345(US8609708, 2 | [5-(pyridin-3-yl)furan-2-yl]methana...)
Affinity DataKi:  100nM ΔG°:  -41.6kJ/molepH: 7.5 T: 2°CAssay Description:To measure CYP2A6 activity, coumarin 7-hydroxylation was determined. The formation of the coumarin metabolite, 7-hydroxycoumarin, was determined fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 50188097BDBM50188097(1-(4-Chlorobenzyl)-1H-imidazole | CHEMBL441367)
Affinity DataIC50: 160nMpH: 7.5Assay Description:To gain insight into the selectivity of the synthetic compounds for inhibition of other CYPs, we examined the major CYPs present in human liver. Prio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2015
Entry Details
US Patent

TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 12341BDBM12341(US8609708, 31 | CHEMBL359657 | US8609708, 1 | CHEM...)
Affinity DataIC50: 160nMpH: 7.5Assay Description:To gain insight into the selectivity of the synthetic compounds for inhibition of other CYPs, we examined the major CYPs present in human liver. Prio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2015
Entry Details
US Patent

TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 12351BDBM12351(US8609708, 4 | CHEMBL179669 | 3-(3-methylthiophen-...)
Affinity DataIC50: 200nMpH: 7.5Assay Description:To gain insight into the selectivity of the synthetic compounds for inhibition of other CYPs, we examined the major CYPs present in human liver. Prio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2015
Entry Details
US Patent

TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 12345BDBM12345(US8609708, 2 | [5-(pyridin-3-yl)furan-2-yl]methana...)
Affinity DataIC50: 200nMpH: 7.5Assay Description:To gain insight into the selectivity of the synthetic compounds for inhibition of other CYPs, we examined the major CYPs present in human liver. Prio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2015
Entry Details
US Patent

TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 12348BDBM12348(US8609708, 3 | 3-(pyridin-3-yl)prop-2-yn-1-amine |...)
Affinity DataKi:  300nM ΔG°:  -38.7kJ/molepH: 7.5 T: 2°CAssay Description:To measure CYP2A6 activity, coumarin 7-hydroxylation was determined. The formation of the coumarin metabolite, 7-hydroxycoumarin, was determined fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 12351BDBM12351(US8609708, 4 | CHEMBL179669 | 3-(3-methylthiophen-...)
Affinity DataKi:  300nM ΔG°:  -38.7kJ/molepH: 7.5 T: 2°CAssay Description:To measure CYP2A6 activity, coumarin 7-hydroxylation was determined. The formation of the coumarin metabolite, 7-hydroxycoumarin, was determined fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 12352BDBM12352(US8609708, 5 | cid_11344157 | 3-(1-methyl-1H-imida...)
Affinity DataKi:  400nM ΔG°:  -38.0kJ/molepH: 7.5 T: 2°CAssay Description:To measure CYP2A6 activity, coumarin 7-hydroxylation was determined. The formation of the coumarin metabolite, 7-hydroxycoumarin, was determined fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 12353BDBM12353(3-(5-methyl-1H-imidazol-1-yl)pyridine | nicotine 3...)
Affinity DataKi:  500nM ΔG°:  -37.4kJ/molepH: 7.5 T: 2°CAssay Description:To measure CYP2A6 activity, coumarin 7-hydroxylation was determined. The formation of the coumarin metabolite, 7-hydroxycoumarin, was determined fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 12370BDBM12370([3-(pyridin-3-yl)-1H-pyrazol-5-yl]methanamine | (3...)
Affinity DataIC50: 600nMpH: 7.5Assay Description:To gain insight into the selectivity of the synthetic compounds for inhibition of other CYPs, we examined the major CYPs present in human liver. Prio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2015
Entry Details
US Patent

TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 12343BDBM12343(CHEMBL369285 | methyl({[5-(pyridin-3-yl)thiophen-2...)
Affinity DataKi:  600nM ΔG°:  -36.9kJ/molepH: 7.5 T: 2°CAssay Description:To measure CYP2A6 activity, coumarin 7-hydroxylation was determined. The formation of the coumarin metabolite, 7-hydroxycoumarin, was determined fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 12354BDBM12354(US8609708,10 | CHEMBL179621 | 2-fluoro-5-(3-methyl...)
Affinity DataKi:  600nM ΔG°:  -36.9kJ/molepH: 7.5 T: 2°CAssay Description:To measure CYP2A6 activity, coumarin 7-hydroxylation was determined. The formation of the coumarin metabolite, 7-hydroxycoumarin, was determined fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 12355BDBM12355(3-(thiophen-3-yl)pyridine | US8609708,11 | CHEMBL3...)
Affinity DataKi:  700nM ΔG°:  -36.5kJ/molepH: 7.5 T: 2°CAssay Description:To measure CYP2A6 activity, coumarin 7-hydroxylation was determined. The formation of the coumarin metabolite, 7-hydroxycoumarin, was determined fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 12356BDBM12356(cid_16654686 | US8609708,13 | CHEMBL368883 | 3-(2-...)
Affinity DataKi:  700nM ΔG°:  -36.5kJ/molepH: 7.5 T: 2°CAssay Description:To measure CYP2A6 activity, coumarin 7-hydroxylation was determined. The formation of the coumarin metabolite, 7-hydroxycoumarin, was determined fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 12371BDBM12371((3-(Pyridin-3-yl)isoxazol-5-yl)methanamine Dihydro...)
Affinity DataIC50: 800nMpH: 7.5Assay Description:To gain insight into the selectivity of the synthetic compounds for inhibition of other CYPs, we examined the major CYPs present in human liver. Prio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2015
Entry Details
US Patent

TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 12346BDBM12346(US8609708,16 | CHEMBL178938 | methyl({[5-(pyridin-...)
Affinity DataKi:  800nM ΔG°:  -36.2kJ/molepH: 7.5 T: 2°CAssay Description:To measure CYP2A6 activity, coumarin 7-hydroxylation was determined. The formation of the coumarin metabolite, 7-hydroxycoumarin, was determined fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 84668BDBM84668(1-Subsituted 1H-imidazole, 3)
Affinity DataIC50: 2.10E+3nMpH: 7.6 T: 2°CAssay Description:Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 84669BDBM84669(1-Subsituted 1H-imidazole, 4)
Affinity DataIC50: 2.70E+3nMpH: 7.6 T: 2°CAssay Description:Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 12349BDBM12349(CHEMBL149808 | US8609708, 26 | methyl[3-(pyridin-3...)
Affinity DataKi:  2.70E+3nM ΔG°:  -33.1kJ/molepH: 7.5 T: 2°CAssay Description:To measure CYP2A6 activity, coumarin 7-hydroxylation was determined. The formation of the coumarin metabolite, 7-hydroxycoumarin, was determined fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 84671BDBM84671(1-Subsituted 1H-imidazole, 7)
Affinity DataIC50: 3.10E+3nMpH: 7.6 T: 2°CAssay Description:Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 84677BDBM84677(1-Subsituted 1H-imidazole, 14)
Affinity DataIC50: 5.70E+3nMpH: 7.6 T: 2°CAssay Description:Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 84673BDBM84673(1-Subsituted 1H-imidazole, 10)
Affinity DataIC50: 6.70E+3nMpH: 7.6 T: 2°CAssay Description:Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 84674BDBM84674(1-Subsituted 1H-imidazole, 12 | 1-Subsituted 1H-im...)
Affinity DataIC50: 7.10E+3nMpH: 7.6 T: 2°CAssay Description:Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 84672BDBM84672(1-Subsituted 1H-imidazole, 9)
Affinity DataIC50: 7.70E+3nMpH: 7.6 T: 2°CAssay Description:Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 84695BDBM84695(2-Subsituted pyrazine, 35)
Affinity DataIC50: 1.03E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 84670BDBM84670(1-Subsituted 1H-imidazole, 5)
Affinity DataIC50: 1.10E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 84693BDBM84693(2-Subsituted pyrazine, 33)
Affinity DataIC50: 1.12E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 84674BDBM84674(1-Subsituted 1H-imidazole, 12 | 1-Subsituted 1H-im...)
Affinity DataIC50: 1.15E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 84676BDBM84676(1-Subsituted 1H-imidazole, 13)
Affinity DataIC50: 1.40E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 12347BDBM12347(US8609708, 56 | CHEMBL360998 | dimethyl({[5-(pyrid...)
Affinity DataKi:  1.42E+4nM ΔG°:  -28.8kJ/molepH: 7.5 T: 2°CAssay Description:To measure CYP2A6 activity, coumarin 7-hydroxylation was determined. The formation of the coumarin metabolite, 7-hydroxycoumarin, was determined fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 84685BDBM84685(1-Subsituted 1H-imidazole, 22)
Affinity DataIC50: 2.24E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 84694BDBM84694(2-Subsituted pyrazine, 34)
Affinity DataIC50: 2.38E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 21358BDBM21358(2-[1-({6-chloroimidazo[2,1-b][1,3]thiazole-5-}sulf...)
Affinity DataIC50: 4.10E+4nMpH: 7.4 T: 2°CAssay Description:The effect of compound on cytochrome P450 (CYP) enzyme catalytic activity was determined in human liver microsomes, using a cocktail of probe substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 50149347BDBM50149347(CHEMBL116766 | 1-Subsituted 1H-imidazole, 6 | 1-Cy...)
Affinity DataIC50: 5.40E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 84678BDBM84678(1-Subsituted 1H-imidazole, 15)
Affinity DataIC50: 6.40E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 12344BDBM12344(US8609708, 75 | dimethyl({[5-(pyridin-3-yl)thiophe...)
Affinity DataKi:  6.65E+4nM ΔG°:  -24.8kJ/molepH: 7.5 T: 2°CAssay Description:To measure CYP2A6 activity, coumarin 7-hydroxylation was determined. The formation of the coumarin metabolite, 7-hydroxycoumarin, was determined fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 12350BDBM12350(US8609708, 76 | CHEMBL180270 | dimethyl[3-(pyridin...)
Affinity DataKi:  6.75E+4nM ΔG°:  -24.8kJ/molepH: 7.5 T: 2°CAssay Description:To measure CYP2A6 activity, coumarin 7-hydroxylation was determined. The formation of the coumarin metabolite, 7-hydroxycoumarin, was determined fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 36010BDBM36010(1-Subsituted 1H-imidazole, 2 | 1-butylimidazole)
Affinity DataIC50: 8.60E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 84667BDBM84667(1-Subsituted 1H-imidazole, 1)
Affinity DataIC50: 1.10E+5nMpH: 7.6 T: 2°CAssay Description:Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 84696BDBM84696(2-Subsituted pyrazine, 36)
Affinity DataIC50: 1.15E+5nMpH: 7.6 T: 2°CAssay Description:Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 84683BDBM84683(1-Subsituted 1H-imidazole, 20)
Affinity DataIC50: 1.22E+5nMpH: 7.6 T: 2°CAssay Description:Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 84679BDBM84679(1-Subsituted 1H-imidazole, 16)
Affinity DataIC50: 1.36E+5nMpH: 7.6 T: 2°CAssay Description:Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 50149352BDBM50149352(1-Cyclohexylmethyl-1H-imidazole | CHEMBL120057)
Affinity DataIC50: 1.70E+5nMpH: 7.5Assay Description:To gain insight into the selectivity of the synthetic compounds for inhibition of other CYPs, we examined the major CYPs present in human liver. Prio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2015
Entry Details
US Patent

TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 84684BDBM84684(CHEMBL543494 | 1-Subsituted 1H-imidazole, 21)
Affinity DataIC50: 1.78E+5nMpH: 7.6 T: 2°CAssay Description:Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 45885BDBM45885(MLS-0091918.0001 | cid_16654684 | 3-(1-imidazolylm...)
Affinity DataIC50: 2.00E+5nMpH: 7.5Assay Description:To gain insight into the selectivity of the synthetic compounds for inhibition of other CYPs, we examined the major CYPs present in human liver. Prio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2015
Entry Details
US Patent

TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 84689BDBM84689(2-Subsituted 1H-imidazole, 28)
Affinity DataIC50: 3.00E+5nMpH: 7.6 T: 2°CAssay Description:Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 84680BDBM84680(1-Subsituted 1H-imidazole, 17)
Affinity DataIC50: 3.00E+5nMpH: 7.6 T: 2°CAssay Description:Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 84687BDBM84687(2-Subsituted 1H-imidazole, 26)
Affinity DataIC50: 3.00E+5nMpH: 7.6 T: 2°CAssay Description:Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

LigandChemical structure of BindingDB Monomer ID 84688BDBM84688(2-Subsituted 1H-imidazole, 27)
Affinity DataIC50: 3.00E+5nMpH: 7.6 T: 2°CAssay Description:Inhibition assay using cytochrome P450 enzyme CYP2A6 and CYP2A13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2012
Entry Details Article
PubMed
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