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Report error Found 149 of ph data with Target = 'D(1A) dopamine receptor'
TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160878BDBM160878(US9107923, 48 | US10093655, Example 48 | US1101490...)
Affinity DataKi:  0.571nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 200951BDBM200951(US9540352, example 5 | 6-[4-(isoquinolin-1-yloxy)-...)
Affinity DataKi:  1.90nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., Dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 50387561BDBM50387561(CHEMBL2057455 | US9359372, DC037079)
Affinity DataKi:  2.53nM ΔG°:  -49.9kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds to D1 and D2 dopamine receptors were determined by competition binding assays. Membrane homogenates of HEK293T cells were s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160912BDBM160912(US9107923, 1 | US9107923, 2 | US10093655, Example ...)
Affinity DataKi:  3.11nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160861BDBM160861(US9107923, 31 | US10093655, Example 31 | US1101490...)
Affinity DataKi:  3.61nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 235778BDBM235778(US9359372, DC037030)
Affinity DataKi:  3.70nM ΔG°:  -48.9kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds to D1 and D2 dopamine receptors were determined by competition binding assays. Membrane homogenates of HEK293T cells were s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160894BDBM160894(US9107923, 64 | US10093655, Example 64 | US1101490...)
Affinity DataKi:  4.17nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160871BDBM160871(US9107923, 41 | US10093655, Example 41 | US1101490...)
Affinity DataKi:  5.41nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 235782BDBM235782(US9359372, DC037035)
Affinity DataKi:  6.72nM ΔG°:  -47.4kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds to D1 and D2 dopamine receptors were determined by competition binding assays. Membrane homogenates of HEK293T cells were s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160883BDBM160883(US10093655, Example 53 | US11014909, Example 53 | ...)
Affinity DataKi:  6.91nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160876BDBM160876(US9107923, 46 | US10093655, Example 46 | US1101490...)
Affinity DataKi:  7.66nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 200985BDBM200985(US9540352, example 11 | 5-[4-(isoquinolin-1-yloxy)...)
Affinity DataKi:  7.80nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., Dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160867BDBM160867(US9107923, 37 | US10093655, Example 37 | US1101490...)
Affinity DataKi:  8.42nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 289097BDBM289097(US10093655, Example 7 | (−)-1,5-Dimethyl-6-(...)
Affinity DataKi:  8.54nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160884BDBM160884(US9107923, 54 | US9107923, 55 | US10093655, Exampl...)
Affinity DataKi:  9.33nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160873BDBM160873(US9107923, 43 | US10093655, Example 43 | US1101490...)
Affinity DataKi:  9.65nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160880BDBM160880(US9107923, 50 | US10093655, Example 50 | US1101490...)
Affinity DataKi:  10.1nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160922BDBM160922(US11014909, Example 11 | BDBM289101 | US9107923, 1...)
Affinity DataKi:  10.9nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160892BDBM160892(US9107923, 62 | US10093655, Example 62 | US1101490...)
Affinity DataKi:  12.1nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 289111BDBM289111(US10093655, Example 19 | 1,5-Dimethyl-6-(7-{[3-(tr...)
Affinity DataKi:  12.9nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160893BDBM160893(US9107923, 63 | US10093655, Example 63 | US1101490...)
Affinity DataKi:  13.4nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160869BDBM160869(US9107923, 39 | US10093655, Example 39 | US1101490...)
Affinity DataKi:  15nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160912BDBM160912(US9107923, 1 | US9107923, 2 | US10093655, Example ...)
Affinity DataKi:  15.3nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160898BDBM160898(US9107923, 68 | US10093655, Example 68 | US1101490...)
Affinity DataKi:  16.9nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 50429046BDBM50429046(CHEMBL2334882 | US9359372, DC037081)
Affinity DataKi:  17.3nM ΔG°:  -45.0kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds to D1 and D2 dopamine receptors were determined by competition binding assays. Membrane homogenates of HEK293T cells were s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 289104BDBM289104(US10093655, Example 14 | (−)-6-(4-{[3-(Diflu...)
Affinity DataKi:  17.5nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160875BDBM160875(US9107923, 45 | US10093655, Example 45 | US1101490...)
Affinity DataKi:  18.6nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 289098BDBM289098(US10093655, Example 8 | (+)-1,5-Dimethyl-6-(2-meth...)
Affinity DataKi:  21nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 235777BDBM235777(US9359372, DC037013 | US9359372, DC037034)
Affinity DataKi:  23.6nM ΔG°:  -44.3kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds to D1 and D2 dopamine receptors were determined by competition binding assays. Membrane homogenates of HEK293T cells were s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160891BDBM160891(US9107923, 61 | US10093655, Example 61 | US1101490...)
Affinity DataKi:  23.8nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160884BDBM160884(US9107923, 54 | US9107923, 55 | US10093655, Exampl...)
Affinity DataKi:  24.2nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160895BDBM160895(US9107923, 65 | US10093655, Example 66 | US1101490...)
Affinity DataKi:  26.9nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 200843BDBM200843(US9540352, example 1 | 1,5-dimethyl-6-[2-methyl-4-...)
Affinity DataKi:  28.5nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., Dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 50387557BDBM50387557(CHEMBL2057457 | US9359372, DC037031)
Affinity DataKi:  28.9nM ΔG°:  -43.8kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds to D1 and D2 dopamine receptors were determined by competition binding assays. Membrane homogenates of HEK293T cells were s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160887BDBM160887(US9107923, 57 | US10093655, Example 57 | US1101490...)
Affinity DataKi:  30.5nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 285641BDBM285641(US10077272, Example 7 | (+)-5-[4-(furo[2,3-d]pyrim...)
Affinity DataKi:  30.7nMpH: 7.4Assay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160868BDBM160868(US9107923, 38 | US10093655, Example 38 | US1101490...)
Affinity DataKi:  31.1nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160908BDBM160908(US9107923, 78 | US10093655, Example 78 | US1101490...)
Affinity DataKi:  32.3nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 285644BDBM285644(US10077272, Example 10 | 4,6-Dimethyl-5-[2-methyl-...)
Affinity DataKi:  32.7nMpH: 7.4Assay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 289096BDBM289096(US10093655, Example 6 | 6-{4-[(3-Chloropyridin-2-y...)
Affinity DataKi:  33.1nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160895BDBM160895(US9107923, 65 | US10093655, Example 66 | US1101490...)
Affinity DataKi:  34.4nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 289109BDBM289109(US10093655, Example 18 | 6-{4-[(3-Chloropyridin-2-...)
Affinity DataKi:  35.7nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160857BDBM160857(US9107923, 27 | US10093655, Example 27 | US1101490...)
Affinity DataKi:  36.2nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160899BDBM160899(US9107923, 69 | US10093655, Example 69 | US1101490...)
Affinity DataKi:  38.3nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160855BDBM160855(US9107923, 25 | US10093655, Example 25 | US1101490...)
Affinity DataKi:  38.5nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 285642BDBM285642(US10077272, Example 8 | (-)-5-[4-(furo[2,3-d]pyrim...)
Affinity DataKi:  40.2nMpH: 7.4Assay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160914BDBM160914(US9107923, 3 | US9107923, 4 | US10093655, Example ...)
Affinity DataKi:  40.6nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 160903BDBM160903(US9107923, 73 | US10093655, Example 73 | US1101490...)
Affinity DataKi:  43.4nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 289106BDBM289106(US10093655, Example 16 | (+)-5-(4-{[3-(Difluoromet...)
Affinity DataKi:  44.3nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 285640BDBM285640(US10077272, Example 6 | 5-[4-(furo[2,3-d]pyrimidin...)
Affinity DataKi:  44.7nMpH: 7.4Assay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

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