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Report error Found 434 of ph data with Target = 'D(2) dopamine receptor'
TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 185688BDBM185688(UNC10107969 | US9156822, 18)
Affinity DataEC50:  0.100nMpH: 7.4Assay Description:HEK293T cells co-expressing the cAMP biosensor GloSensor-22F (Promega) and hD2 receptors were seeded (10,000 cells/20 ul/well) into white, clear-bott...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194790BDBM194790(US9206167, 12 | US9206167, 11 | USRE48059, Compoun...)
Affinity DataKi:  0.100nM ΔG°:  -57.1kJ/molepH: 7.4 T: 2°CAssay Description:The assay was performed according to the method by Kohler et al. (Kohler C, Hall H, Ogren S O and Gawell L, Specific in vitro and in vivo binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194790BDBM194790(US9206167, 12 | US9206167, 11 | USRE48059, Compoun...)
Affinity DataKi:  0.100nM ΔG°:  -57.1kJ/molepH: 7.4 T: 2°CAssay Description:The assay was performed according to the method by Kohler et al. (Kohler C, Hall H, Ogren S O and Gawell L, Specific in vitro and in vivo binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 50207094BDBM50207094(CHEMBL3976282 | US9550741, I-2)
Affinity DataKi:  0.190nMpH: 7.5Assay Description:1. Experimental Materials:(1) D2 receptor Cell Transfection:This experiment utilizes the plasmid vector containing the gene of D2 receptor protein fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 50207094BDBM50207094(CHEMBL3976282 | US9550741, I-2)
Affinity DataKi:  0.190nMpH: 7.5Assay Description:1. Experimental Materials:(1) D2 receptor Cell Transfection:This experiment utilizes the plasmid vector containing the gene of D2 receptor protein fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194794BDBM194794(US9206167, 15 | USRE48059, Compound of Example 15)
Affinity DataKi:  0.200nM ΔG°:  -55.4kJ/molepH: 7.4 T: 2°CAssay Description:The assay was performed according to the method by Kohler et al. (Kohler C, Hall H, Ogren S O and Gawell L, Specific in vitro and in vivo binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 185687BDBM185687(UNC10107968 | US9156822, 17)
Affinity DataEC50:  0.200nMpH: 7.4Assay Description:HEK293T cells co-expressing the cAMP biosensor GloSensor-22F (Promega) and hD2 receptors were seeded (10,000 cells/20 ul/well) into white, clear-bott...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194772BDBM194772(US9206167, 139)
Affinity DataKi:  0.200nM ΔG°:  -55.4kJ/molepH: 7.4 T: 2°CAssay Description:The assay was performed according to the method by Kohler et al. (Kohler C, Hall H, Ogren S O and Gawell L, Specific in vitro and in vivo binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194780BDBM194780(US9206167, 1 | brexpiprazole | 7-(4-(4-(1-benzothi...)
Affinity DataKi:  0.200nM ΔG°:  -55.4kJ/molepH: 7.4 T: 2°CAssay Description:The assay was performed according to the method by Kohler et al. (Kohler C, Hall H, Ogren S O and Gawell L, Specific in vitro and in vivo binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 50207156BDBM50207156(CHEMBL3938210 | US9550741, I-3)
Affinity DataKi:  0.210nMpH: 7.5Assay Description:1. Experimental Materials:(1) D2 receptor Cell Transfection:This experiment utilizes the plasmid vector containing the gene of D2 receptor protein fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 50207156BDBM50207156(CHEMBL3938210 | US9550741, I-3)
Affinity DataKi:  0.210nMpH: 7.5Assay Description:1. Experimental Materials:(1) D2 receptor Cell Transfection:This experiment utilizes the plasmid vector containing the gene of D2 receptor protein fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 263384BDBM263384(US9550741, I-18)
Affinity DataKi:  0.230nMpH: 7.5Assay Description:1. Experimental Materials:(1) D2 receptor Cell Transfection:This experiment utilizes the plasmid vector containing the gene of D2 receptor protein fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 263384BDBM263384(US9550741, I-18)
Affinity DataKi:  0.230nMpH: 7.5Assay Description:1. Experimental Materials:(1) D2 receptor Cell Transfection:This experiment utilizes the plasmid vector containing the gene of D2 receptor protein fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 263383BDBM263383(US9550741, I-17)
Affinity DataKi:  0.270nMpH: 7.5Assay Description:1. Experimental Materials:(1) D2 receptor Cell Transfection:This experiment utilizes the plasmid vector containing the gene of D2 receptor protein fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 263383BDBM263383(US9550741, I-17)
Affinity DataKi:  0.270nMpH: 7.5Assay Description:1. Experimental Materials:(1) D2 receptor Cell Transfection:This experiment utilizes the plasmid vector containing the gene of D2 receptor protein fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 185696BDBM185696(UNC10108017 | US9156822, 40)
Affinity DataKi:  0.300nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 263371BDBM263371(US9550741, I-5)
Affinity DataKi:  0.320nMpH: 7.5Assay Description:1. Experimental Materials:(1) D2 receptor Cell Transfection:This experiment utilizes the plasmid vector containing the gene of D2 receptor protein fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 50349866BDBM50349866(CHEMBL1813590 | CHEMBL160296 | UNC10108016 | US915...)
Affinity DataKi:  0.320nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 263371BDBM263371(US9550741, I-5)
Affinity DataKi:  0.320nMpH: 7.5Assay Description:1. Experimental Materials:(1) D2 receptor Cell Transfection:This experiment utilizes the plasmid vector containing the gene of D2 receptor protein fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194764BDBM194764(US9206167, 90)
Affinity DataKi:  0.400nM ΔG°:  -53.6kJ/molepH: 7.4 T: 2°CAssay Description:The assay was performed according to the method by Kohler et al. (Kohler C, Hall H, Ogren S O and Gawell L, Specific in vitro and in vivo binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 185698BDBM185698(UNC10108019 | US9156822, 42)
Affinity DataKi:  0.400nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 185695BDBM185695(UNC10108010 | US9156822, 38)
Affinity DataEC50:  0.400nMpH: 7.4Assay Description:Recruitment of β-arrestin to agonist-stimulated D2 receptors was performed using a previously described Tango-type assay (Barnea et al., Proc. N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 185697BDBM185697(UNC10108018 | US9156822, 41)
Affinity DataEC50:  0.400nMpH: 7.4Assay Description:HEK293T cells co-expressing the cAMP biosensor GloSensor-22F (Promega) and hD2 receptors were seeded (10,000 cells/20 ul/well) into white, clear-bott...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194789BDBM194789(US9206167, 10 | USRE48059, Compound of Example 10)
Affinity DataKi:  0.400nM ΔG°:  -53.6kJ/molepH: 7.4 T: 2°CAssay Description:The assay was performed according to the method by Kohler et al. (Kohler C, Hall H, Ogren S O and Gawell L, Specific in vitro and in vivo binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 50207116BDBM50207116(CHEMBL3905247 | US9550741, I-4)
Affinity DataKi:  0.430nMpH: 7.5Assay Description:1. Experimental Materials:(1) D2 receptor Cell Transfection:This experiment utilizes the plasmid vector containing the gene of D2 receptor protein fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 50207143BDBM50207143(CHEMBL3966842 | US9550741, II-1)
Affinity DataKi:  0.430nMpH: 7.5Assay Description:1. Experimental Materials:(1) D2 receptor Cell Transfection:This experiment utilizes the plasmid vector containing the gene of D2 receptor protein fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 50207116BDBM50207116(CHEMBL3905247 | US9550741, I-4)
Affinity DataKi:  0.430nMpH: 7.5Assay Description:1. Experimental Materials:(1) D2 receptor Cell Transfection:This experiment utilizes the plasmid vector containing the gene of D2 receptor protein fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 50207143BDBM50207143(CHEMBL3966842 | US9550741, II-1)
Affinity DataKi:  0.430nMpH: 7.5Assay Description:1. Experimental Materials:(1) D2 receptor Cell Transfection:This experiment utilizes the plasmid vector containing the gene of D2 receptor protein fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 185697BDBM185697(UNC10108018 | US9156822, 41)
Affinity DataKi:  0.450nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 185695BDBM185695(UNC10108010 | US9156822, 38)
Affinity DataKi:  0.470nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 50349866BDBM50349866(CHEMBL1813590 | CHEMBL160296 | UNC10108016 | US915...)
Affinity DataEC50:  0.5nMpH: 7.4Assay Description:Recruitment of β-arrestin to agonist-stimulated D2 receptors was performed using a previously described Tango-type assay (Barnea et al., Proc. N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194786BDBM194786(US9206167, 7 | USRE48059, Compound of Example 7)
Affinity DataKi:  0.5nM ΔG°:  -53.1kJ/molepH: 7.4 T: 2°CAssay Description:The assay was performed according to the method by Kohler et al. (Kohler C, Hall H, Ogren S O and Gawell L, Specific in vitro and in vivo binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194782BDBM194782(US9206167, 3 | USRE48059, Compound of Example 3)
Affinity DataKi:  0.5nM ΔG°:  -53.1kJ/molepH: 7.4 T: 2°CAssay Description:The assay was performed according to the method by Kohler et al. (Kohler C, Hall H, Ogren S O and Gawell L, Specific in vitro and in vivo binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194783BDBM194783(US9206167, 4 | USRE48059, Compound of Example 4)
Affinity DataKi:  0.5nM ΔG°:  -53.1kJ/molepH: 7.4 T: 2°CAssay Description:The assay was performed according to the method by Kohler et al. (Kohler C, Hall H, Ogren S O and Gawell L, Specific in vitro and in vivo binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 263395BDBM263395(US9550741, II-5)
Affinity DataKi:  0.580nMpH: 7.5Assay Description:1. Experimental Materials:(1) D2 receptor Cell Transfection:This experiment utilizes the plasmid vector containing the gene of D2 receptor protein fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 263395BDBM263395(US9550741, II-5)
Affinity DataKi:  0.580nMpH: 7.5Assay Description:1. Experimental Materials:(1) D2 receptor Cell Transfection:This experiment utilizes the plasmid vector containing the gene of D2 receptor protein fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 185697BDBM185697(UNC10108018 | US9156822, 41)
Affinity DataEC50:  0.600nMpH: 7.4Assay Description:Recruitment of β-arrestin to agonist-stimulated D2 receptors was performed using a previously described Tango-type assay (Barnea et al., Proc. N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194784BDBM194784(US9206167, 5 | USRE48059, Compound of Example 5)
Affinity DataKi:  0.600nM ΔG°:  -52.6kJ/molepH: 7.4 T: 2°CAssay Description:The assay was performed according to the method by Kohler et al. (Kohler C, Hall H, Ogren S O and Gawell L, Specific in vitro and in vivo binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194795BDBM194795(US9206167, 16 | USRE48059, Compound of Example 16)
Affinity DataKi:  0.700nM ΔG°:  -52.3kJ/molepH: 7.4 T: 2°CAssay Description:The assay was performed according to the method by Kohler et al. (Kohler C, Hall H, Ogren S O and Gawell L, Specific in vitro and in vivo binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194808BDBM194808(US9206167, 30 | USRE48059, Compound of Example 30 ...)
Affinity DataKi:  0.700nM ΔG°:  -52.3kJ/molepH: 7.4 T: 2°CAssay Description:The assay was performed according to the method by Kohler et al. (Kohler C, Hall H, Ogren S O and Gawell L, Specific in vitro and in vivo binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194802BDBM194802(US9206167, 23 | USRE48059, Compound of Example 23)
Affinity DataKi:  0.700nM ΔG°:  -52.3kJ/molepH: 7.4 T: 2°CAssay Description:The assay was performed according to the method by Kohler et al. (Kohler C, Hall H, Ogren S O and Gawell L, Specific in vitro and in vivo binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 50207158BDBM50207158(CHEMBL3982486 | US9550741, III-2)
Affinity DataKi:  0.710nMpH: 7.5Assay Description:1. Experimental Materials:(1) D2 receptor Cell Transfection:This experiment utilizes the plasmid vector containing the gene of D2 receptor protein fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 50207158BDBM50207158(CHEMBL3982486 | US9550741, III-2)
Affinity DataKi:  0.710nMpH: 7.5Assay Description:1. Experimental Materials:(1) D2 receptor Cell Transfection:This experiment utilizes the plasmid vector containing the gene of D2 receptor protein fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 263449BDBM263449(US9550741, RGH-188)
Affinity DataKi:  0.780nMpH: 7.5Assay Description:1. Experimental Materials:(1) D2 receptor Cell Transfection:This experiment utilizes the plasmid vector containing the gene of D2 receptor protein fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 263438BDBM263438(US9550741, IV-4)
Affinity DataKi:  0.800nMpH: 7.5Assay Description:1. Experimental Materials:(1) D2 receptor Cell Transfection:This experiment utilizes the plasmid vector containing the gene of D2 receptor protein fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194760BDBM194760(US9206167, 81)
Affinity DataKi:  0.800nM ΔG°:  -51.9kJ/molepH: 7.4 T: 2°CAssay Description:The assay was performed according to the method by Kohler et al. (Kohler C, Hall H, Ogren S O and Gawell L, Specific in vitro and in vivo binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194779BDBM194779(US9206167, 190)
Affinity DataKi:  0.800nM ΔG°:  -51.9kJ/molepH: 7.4 T: 2°CAssay Description:The assay was performed according to the method by Kohler et al. (Kohler C, Hall H, Ogren S O and Gawell L, Specific in vitro and in vivo binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194756BDBM194756(US9206167, 69)
Affinity DataKi:  0.800nM ΔG°:  -51.9kJ/molepH: 7.4 T: 2°CAssay Description:The assay was performed according to the method by Kohler et al. (Kohler C, Hall H, Ogren S O and Gawell L, Specific in vitro and in vivo binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 194785BDBM194785(US9206167, 6 | USRE48059, Compound of Example 6)
Affinity DataKi:  0.800nM ΔG°:  -51.9kJ/molepH: 7.4 T: 2°CAssay Description:The assay was performed according to the method by Kohler et al. (Kohler C, Hall H, Ogren S O and Gawell L, Specific in vitro and in vivo binding of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 263438BDBM263438(US9550741, IV-4)
Affinity DataKi:  0.800nMpH: 7.5Assay Description:1. Experimental Materials:(1) D2 receptor Cell Transfection:This experiment utilizes the plasmid vector containing the gene of D2 receptor protein fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

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