Compile Data Set for Download or QSAR
Report error Found 268 of ph data with Target = 'D-amino-acid oxidase'
TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 196658BDBM196658(US9212147, 15 | US10202399, Example 15)
Affinity DataIC50: 1.20nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50431067BDBM50431067(CHEMBL2338797 | US9290456, 6 | US9212147, 18 | US1...)
Affinity DataIC50: 1.40nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50431083BDBM50431083(CHEMBL2338803 | US9290456, 8 | US9212147, 24 | US1...)
Affinity DataIC50: 1.5nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50431069BDBM50431069(CHEMBL2338795 | US9290456, 7 | US9212147, 27 | US1...)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 196659BDBM196659(US9212147, 16)
Affinity DataIC50: 2.10nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 196675BDBM196675(US9212147, 237 | US10202399, Example 237)
Affinity DataIC50: 2.20nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 196661BDBM196661(US9290456, 17 | US9212147, 21 | US10202399, Exampl...)
Affinity DataIC50: 2.20nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 196674BDBM196674(US9212147, 232 | US10202399, Example 232)
Affinity DataIC50: 2.30nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 196671BDBM196671(US9212147, 56 | US10202399, Example 56)
Affinity DataIC50: 2.30nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50431066BDBM50431066(CHEMBL2338798 | US9290456, 11 | US9212147, 17 | US...)
Affinity DataIC50: 2.40nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 196654BDBM196654(US9212147, 1)
Affinity DataIC50: 2.40nMpH: 7.5 T: 2°CAssay Description:This test was performed by partially modifying the method of Philip et. al. (J. Biomol. Screen. Vol. 11, pp 481-487, 2006). HEK293 cells that stably ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 196670BDBM196670(US9212147, 52 | US10202399, Example 52)
Affinity DataIC50: 2.5nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 196660BDBM196660(US9212147, 20 | US10202399, Example 20)
Affinity DataIC50: 2.5nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50431074BDBM50431074(CHEMBL2338790 | US9290456, 27 | US9212147, 254 | U...)
Affinity DataIC50: 2.70nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 196657BDBM196657(US9212147, 14)
Affinity DataIC50: 2.90nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 196673BDBM196673(US9212147, 231 | US10202399, Example 231)
Affinity DataIC50: 2.90nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 31173BDBM31173(naphthyridinone analog., 27)
Affinity DataIC50: 3nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 31149BDBM31149(3-hydroxyquinolin-2(1H)-one, 3)
Affinity DataIC50: 3nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50431086BDBM50431086(CHEMBL2338800 | US9290456, 2 | US9212147, 212 | US...)
Affinity DataIC50: 3.10nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 196662BDBM196662(US9212147, 22 | US10202399, Example 22)
Affinity DataIC50: 3.30nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 196655BDBM196655(US9212147, 4 | US10202399, Example 4)
Affinity DataIC50: 3.5nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 210775BDBM210775(US9290456, 4 | US9931340, Example 4 | US10463663, ...)
Affinity DataIC50: 3.70nMpH: 7.4 T: 2°CAssay Description:Human DAAO enzyme was supplied by the Takeda Pharmaceutical Company (Osaka) and each batch was tested and used at concentrations giving comparable le...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 196654BDBM196654(US9212147, 1)
Affinity DataIC50: 3.80nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50431079BDBM50431079(CHEMBL2338785 | US9180122, 27 | US9212147, 9 | US1...)
Affinity DataIC50: 3.90nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 31156BDBM31156(3-hydroxyquinolin-2(1H)-one, 10)
Affinity DataIC50: 4nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 31148BDBM31148(3-hydroxyquinolin-2(1H)-one, 2 | US9701638, 1)
Affinity DataIC50: 4nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50431069BDBM50431069(CHEMBL2338795 | US9290456, 7 | US9212147, 27 | US1...)
Affinity DataIC50: 4.40nMpH: 7.5 T: 2°CAssay Description:This test was performed by partially modifying the method of Philip et. al. (J. Biomol. Screen. Vol. 11, pp 481-487, 2006). HEK293 cells that stably ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 196660BDBM196660(US9212147, 20 | US10202399, Example 20)
Affinity DataIC50: 4.60nMpH: 7.5 T: 2°CAssay Description:This test was performed by partially modifying the method of Philip et. al. (J. Biomol. Screen. Vol. 11, pp 481-487, 2006). HEK293 cells that stably ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 196668BDBM196668(US9212147, 40)
Affinity DataIC50: 4.70nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50431077BDBM50431077(CHEMBL2338787 | US9290456, 56 | US9212147, 48 | US...)
Affinity DataIC50: 4.90nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 31172BDBM31172(3-hydroxyquinolin-2(1H)-one, 26)
Affinity DataIC50: 5nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 196675BDBM196675(US9212147, 237 | US10202399, Example 237)
Affinity DataIC50: 5.10nMpH: 7.5 T: 2°CAssay Description:This test was performed by partially modifying the method of Philip et. al. (J. Biomol. Screen. Vol. 11, pp 481-487, 2006). HEK293 cells that stably ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 196669BDBM196669(US9212147, 47)
Affinity DataIC50: 5.20nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 196661BDBM196661(US9290456, 17 | US9212147, 21 | US10202399, Exampl...)
Affinity DataIC50: 5.5nMpH: 7.5 T: 2°CAssay Description:This test was performed by partially modifying the method of Philip et. al. (J. Biomol. Screen. Vol. 11, pp 481-487, 2006). HEK293 cells that stably ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 210789BDBM210789(US9290456, 24 | US9931340, Example 24 | US10463663...)
Affinity DataIC50: 6nMpH: 7.4 T: 2°CAssay Description:Human DAAO enzyme was supplied by the Takeda Pharmaceutical Company (Osaka) and each batch was tested and used at concentrations giving comparable le...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50431067BDBM50431067(CHEMBL2338797 | US9290456, 6 | US9212147, 18 | US1...)
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:This test was performed by partially modifying the method of Philip et. al. (J. Biomol. Screen. Vol. 11, pp 481-487, 2006). HEK293 cells that stably ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 196656BDBM196656(US9212147, 13 | US10202399, Example 13)
Affinity DataIC50: 6.10nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50431074BDBM50431074(CHEMBL2338790 | US9290456, 27 | US9212147, 254 | U...)
Affinity DataIC50: 6.30nMpH: 7.5 T: 2°CAssay Description:This test was performed by partially modifying the method of Philip et. al. (J. Biomol. Screen. Vol. 11, pp 481-487, 2006). HEK293 cells that stably ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 196664BDBM196664(US9212147, 25 | US10202399, Example 25)
Affinity DataIC50: 6.60nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 196667BDBM196667(US9212147, 29 | US10202399, Example 29)
Affinity DataIC50: 6.90nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50431083BDBM50431083(CHEMBL2338803 | US9290456, 8 | US9212147, 24 | US1...)
Affinity DataIC50: 7nMpH: 7.5 T: 2°CAssay Description:This test was performed by partially modifying the method of Philip et. al. (J. Biomol. Screen. Vol. 11, pp 481-487, 2006). HEK293 cells that stably ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50431086BDBM50431086(CHEMBL2338800 | US9290456, 2 | US9212147, 212 | US...)
Affinity DataIC50: 7.20nMpH: 7.5 T: 2°CAssay Description:This test was performed by partially modifying the method of Philip et. al. (J. Biomol. Screen. Vol. 11, pp 481-487, 2006). HEK293 cells that stably ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 31161BDBM31161(3-hydroxyquinolin-2(1H)-one, 15)
Affinity DataIC50: 8nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 31164BDBM31164(naphthyridinone analog.,18)
Affinity DataIC50: 8nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 31152BDBM31152(3-hydroxyquinolin-2(1H)-one, 6)
Affinity DataIC50: 8nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 196666BDBM196666(US9212147, 28)
Affinity DataIC50: 8.10nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 196665BDBM196665(US9212147, 26)
Affinity DataIC50: 8.10nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50431066BDBM50431066(CHEMBL2338798 | US9290456, 11 | US9212147, 17 | US...)
Affinity DataIC50: 8.30nMpH: 7.5 T: 2°CAssay Description:This test was performed by partially modifying the method of Philip et. al. (J. Biomol. Screen. Vol. 11, pp 481-487, 2006). HEK293 cells that stably ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50431068BDBM50431068(CHEMBL2338796 | US9290456, 29 | US9212147, 30 | US...)
Affinity DataIC50: 8.40nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 210785BDBM210785(US9290456, 20 | US9931340, Example 20 | US10463663...)
Affinity DataIC50: 8.40nMpH: 7.4 T: 2°CAssay Description:Human DAAO enzyme was supplied by the Takeda Pharmaceutical Company (Osaka) and each batch was tested and used at concentrations giving comparable le...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
US Patent

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