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Found 3 of ph data with Target = 'Epidermal growth factor receptor [1-973]'
TargetEpidermal growth factor receptor [1-973](Homo sapiens (Human))
Shenyang Pharmaceutical University

LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)
Affinity DataIC50:  2.99E+3nMpH: 7.0 T: 2°CAssay Description:The c-Met kinase activity was evaluated by homogeneous time-resolved fluorescence (HTRF) assays. In a 384-well plate, 20 µg/mL (Glue, Tyr) 4:1 w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor [1-973](Homo sapiens (Human))
Shenyang Pharmaceutical University

LigandPNGBDBM120816((Z)-4-(((3-fluoro-4-((6-methoxy-7-(3-morpholinopro...)
Affinity DataIC50: >1.00E+4nMpH: 7.0 T: 2°CAssay Description:The c-Met kinase activity was evaluated by homogeneous time-resolved fluorescence (HTRF) assays. In a 384-well plate, 20 µg/mL (Glue, Tyr) 4:1 w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor [1-973](Homo sapiens (Human))
Shenyang Pharmaceutical University

LigandPNGBDBM110206(1-[2-(Dimethylamino)ethyl]-5-(2-hydroxy-4-methoxyb...)
Affinity DataIC50: >3.00E+5nMpH: 7.0Assay Description:EGFR was incubated with 8 mM MOPS (pH 7.0), 0.2 mM EDTA, 10 mM MnCl2, 0.1 mg/mL poly(Glu, Tyr) 4:1. MAPK1 was incubated with 25 mM Tris (pH 7.5), 0.0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed