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Found 30 of ph data with Target = 'Geranylgeranyl pyrophosphate synthase'
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25256(bisphosphonate, 9 | hydrogen [2-(dodecyldimethylph...)
Affinity DataIC50:  100nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25258(3-(decyloxy)-5-(2-hydrogen phosphonato-2-phosphono...)
Affinity DataIC50:  280nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25259(3-(decyloxy)-1-(2-hydrogen phosphonato-2-phosphono...)
Affinity DataIC50:  280nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25260(bisphosphonate, 16 | {2-[dodecyl(methyl)amino]-1-p...)
Affinity DataIC50:  350nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25261(3-decyl-1-(2-hydrogen phosphonato-2-phosphonoethyl...)
Affinity DataIC50:  400nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25262(3-bromo-5-(decyloxy)-1-(2-hydrogen phosphonato-2-p...)
Affinity DataIC50:  510nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25263(bisphosphonate, 19 | {2-[3-(decyloxy)phenyl]-1-hyd...)
Affinity DataIC50:  590nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25264(1-(2-hydrogen phosphonato-2-phosphonoethyl)-4-octy...)
Affinity DataIC50:  660nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25265((1-hydroxy-1-phosphonononyl)phosphonic acid | CHEM...)
Affinity DataIC50:  710nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25266(BPH-628 | bisphosphonate, 21 | {1-hydroxy-2-[3-(4-...)
Affinity DataIC50:  720nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25267(3-(decyloxy)-5-(3,5-difluorophenyl)-1-(2-hydrogen ...)
Affinity DataIC50:  760nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25268(bisphosphonate, 22 | hydrogen {2-[dimethyl(octyl)p...)
Affinity DataIC50:  890nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25269((1-hydroxy-1-phosphonodecyl)phosphonic acid | CHEM...)
Affinity DataIC50:  890nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25270([(6E,11E)-2,6,12,16-tetramethyl-9-phosphonoheptade...)
Affinity DataIC50:  980nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25271(3-[(3,7-dimethyloctyl)oxy]-1-(2-hydrogen phosphona...)
Affinity DataIC50:  1.15E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25272(CHEMBL238046 | bisphosphonate, 25 | hydrogen {2-[d...)
Affinity DataIC50:  1.23E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25273(3-(decylamino)-1-(2-hydrogen phosphonato-2-phospho...)
Affinity DataIC50:  1.26E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25274(1-(2-hydrogen phosphonato-2-hydroxy-2-phosphonoeth...)
Affinity DataIC50:  1.38E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25275(CHEMBL237808 | bisphosphonate, 28 | hydrogen {2-[m...)
Affinity DataIC50:  1.48E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25276(1-(2-hydrogen phosphonato-2-phosphonoethyl)-3-(oct...)
Affinity DataIC50:  1.74E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25277([(6E,11E)-9-phosphonoheptadeca-6,11-dien-9-yl]phos...)
Affinity DataIC50:  1.86E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25278(3-(heptyloxy)-5-(2-hydrogen phosphonato-2-phosphon...)
Affinity DataIC50:  2.14E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25279(BPH-608 | bisphosphonate, 31 | {1-hydroxy-2-[3-(3-...)
Affinity DataIC50:  2.14E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25280(bisphosphonate, 32 | {1-[3-(decyloxy)phenyl]-2-pho...)
Affinity DataIC50:  2.34E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25281((9-phosphonoheptadecan-9-yl)phosphonic acid | bisp...)
Affinity DataIC50:  2.51E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25282(1-(2-hydrogen phosphonato-2-phosphonoethyl)-3-(oct...)
Affinity DataIC50:  2.51E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25283(3-(3-butoxyphenyl)-1-(2-hydrogen phosphonato-2-pho...)
Affinity DataIC50:  2.51E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25284((1-hydroxy-2-{3-[3-(naphthalene-2-sulfonamido)phen...)
Affinity DataIC50:  2.69E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25285((1-hydroxy-1-phosphonododecyl)phosphonic acid | CH...)
Affinity DataIC50:  2.69E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Taiwan University

LigandPNGBDBM25286(3-(dodecyloxy)-1-(2-hydrogen phosphonato-2-phospho...)
Affinity DataIC50:  3.02E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed