Compile Data Set for Download or QSAR
maximum 50k data
Found 2 of ph data with Target = 'Geranylgeranyl transferase type-1 subunit beta [A2V]/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha'
LigandPNGBDBM14713(GGTI-DU40 | N-[(1S)-1-carbamoyl-2-phenylethyl]-4-{...)
Affinity DataIC50:  8.24nMpH: 7.7 T: 2°CAssay Description:Compounds were tested as inhibitors of FTase or GGTase-1 in vitro using purified recombinant mammalian enzymes to catalyze the reactions between [3H]...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14434(6-[amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl...)
Affinity DatapH: 7.5 T: 2°CAssay Description:Compounds were tested as inhibitors of GGTase-1 in vitro using purified human enzyme to catalyze the reaction between [3H] GGPP and a biotinylated pe...More data for this Ligand-Target Pair