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Found 1021 of ph data with Target = 'Lysine-specific histone demethylase 1A'
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM182862(US9670136, 1 N1-((trans)-2-phenylcyclopropyl)cyclo...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179672(US9676701, 31 (trans)-2-(6-(5-chlorothiophen-2-yl)...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM254546(US10214477, Example 3 | US9469597, 1 | US9670136, ...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM254553(US9469597, 12 | US9670136, 12 4-(((trans)-2-(6-(3-...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM254556(US10214477, Example 15 | US9469597, 15 | US9670136...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179724(US9676701, 46 5-(5-((trans)-2-aminocyclopropyl)pyr...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179729(US9676701, 48 3-(5-((trans)-2-amninocyclopropyl)py...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179740(US9676701, 53 N-(3-(5-((trans)-2-aminocyclopropyl)...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179745(US9676701, 56 5-(5-((trans)-2-aminocyclopropyl)pyr...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179823(US9676701, 59 5-(5-((trans)-2-aminocyclopropyl)pyr...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM254546(US10214477, Example 3 | US9469597, 1 | US9670136, ...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179670(US9676701, 29 3-(5-((trans)-2-aminocyclopropyl)pyr...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179654(US9676701, 25 3-(5-((trans)-2-aminocyclopropyl)pyr...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179653(US9676701, 24 3-(5-((trans)-2-aminocyclopropyl)pyr...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179652(US9676701, 23 5-(5-((trans)-2-aminocyclopropyl)pyr...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179646(US9676701, 17 3-(5-((trans)-2-aminocyclopropyl)pyr...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179649(US9676701, 20 2-(5-((trans)-2-aminocyclopropyl)pyr...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179646(US9676701, 17 3-(5-((trans)-2-aminocyclopropyl)pyr...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179641(US9676701, 13 3-(5-((trans)-2-aminocyclopropyl)pyr...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179446(US9676701, 4 4′-((trans)-2-aminocyclopropyl)...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179984(US9676701, 124 N-(3-(5-((trans)-2-aminocyclopropyl...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179976(US9676701, 116 3-(5-((trans)-2-aminocyclopropyl)th...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179973(US9676701, 113 3-(5-((trans)-2-aminocyclopropyl)th...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179933(US9676701, 102 N-(3-(5-((trans)-2-aminocyclopropyl...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179906(US9676701, 101 N-(3-(5-((trans)-2-aminocyclopropyl...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179905(US9676701, 100 N-(3-(5-((trans)-2-aminocyclopropyl...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179865(US9676701, 99 N-(3-(5-((trans)-2-aminocyclopropyl)...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM50445349(CHEMBL3104261 | US9676701, 63 Enantiomers of 4R...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM50445349(CHEMBL3104261 | US9676701, 63 Enantiomers of 4R...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179828(US9676701, 64 N-(3-(5-((trans)-2-aminocyclopropyl)...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179829(US9676701, 65 N-(3-(5-((trans)-2-aminocyclopropyl)...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179830(US9676701, 66 4′-((trans)-2-aminocyclopropyl...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179832(US9676701, 67 4′-((trans)-2-aminocyclopropyl...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179833(US9676701, 68 N-(4′-((trans)-2-aminocyclopro...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM50158875(CHEMBL3787372 | US9676701, 69 N-(4′-((trans)...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179835(US9676701, 70 N-(4′-((trans)-2-aminocyclopro...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179840(US9676701, 75 N-(4′-((trans)-2-aminocyclopro...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179854(US9676701, 88 N-(4′-((trans)-2-aminocyclopro...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179855(US9676701, 89 3-(5-((trans)-2-aminocyclopropyl)pyr...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179856(US9676701, 90 N-(3-(5-((trans)-2-aminocyclopropyl)...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179860(US9676701, 94 N-(4′-((trans)-2-aminocyclopro...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179861(US9676701, 95 N-(3-(5-((trans)-2-aminocyclopropyl)...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179862(US9676701, 96 N-(4′-((trans)-2-aminocyclopro...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM179864(US9676701, 98 N-(3-(5-((trans)-2-aminocyclopropyl)...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM113742(N-[4-(2-Hydrazinylethyl)phenyl]-4-phenylbutanamide...)
Affinity DataKi:  59nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM113753(N-[4-(2-Hydrazinylethyl)phenyl]-4-(1H-indol-3-yl)b...)
Affinity DataKi:  100nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM113750((2E)-N-[4-(2-Hydrazinylethyl)phenyl]-3-phenylprop-...)
Affinity DataKi:  100nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM113745(4-(4-Fluorophenyl)-N-[4-(2-hydrazinylethyl)phenyl]...)
Affinity DataKi:  138nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM113744(4-(4-Chlorophenyl)-N-[4-(2-hydrazinylethyl)phenyl]...)
Affinity DataKi:  156nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM113748(2-(3-{[4-(2-Hydrazinylethyl)phenyl]amino}-3-oxopro...)
Affinity DataKi:  204nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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