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Found 7 of ph data with Target = 'NAD-dependent protein deacetylase sirtuin-2'
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234208(US9359293, TM)
Affinity DataIC50:  50nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234207(US9359293, TH)
Affinity DataIC50:  120nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234206(US9359293, TB)
Affinity DataIC50:  3.00E+3nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM227596(AEM2)
Affinity DataIC50:  3.80E+3nMpH: 8.0 T: 2°CAssay Description:Deacetylation assays using Boc(Ac)Lys-7-amino-4-methyl-coumarin (MAL; Bachem, Bubendorf, Switzerland) as a substrate were performed in a volume of 20...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM227595(AEM1)
Affinity DataIC50:  1.85E+4nMpH: 8.0 T: 2°CAssay Description:Deacetylation assays using Boc(Ac)Lys-7-amino-4-methyl-coumarin (MAL; Bachem, Bubendorf, Switzerland) as a substrate were performed in a volume of 20...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM227597(AEM1 derivative, 1)
Affinity DataIC50:  1.87E+4nMpH: 8.0 T: 2°CAssay Description:Deacetylation assays using Boc(Ac)Lys-7-amino-4-methyl-coumarin (MAL; Bachem, Bubendorf, Switzerland) as a substrate were performed in a volume of 20...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234205(US9359293, TA)
Affinity DataIC50:  1.05E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent