Affinity DataIC50: 50nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+3nMpH: 8.0 T: 2°CAssay Description:Deacetylation assays using Boc(Ac)Lys-7-amino-4-methyl-coumarin (MAL; Bachem, Bubendorf, Switzerland) as a substrate were performed in a volume of 20...More data for this Ligand-Target Pair
Affinity DataIC50: 1.85E+4nMpH: 8.0 T: 2°CAssay Description:Deacetylation assays using Boc(Ac)Lys-7-amino-4-methyl-coumarin (MAL; Bachem, Bubendorf, Switzerland) as a substrate were performed in a volume of 20...More data for this Ligand-Target Pair
Affinity DataIC50: 1.87E+4nMpH: 8.0 T: 2°CAssay Description:Deacetylation assays using Boc(Ac)Lys-7-amino-4-methyl-coumarin (MAL; Bachem, Bubendorf, Switzerland) as a substrate were performed in a volume of 20...More data for this Ligand-Target Pair
Affinity DataIC50: 1.05E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair