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Found 114 of ph data with Target = 'Prokineticin receptor 1'
TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM26335(3-[2-({5-[(4-ethylphenyl)methyl]-1-[(4-methoxyphen...)
Affinity DataKi:  22nM ΔG°:  -45.5kJ/molepH: 7.4 T: 2°CAssay Description:Nonspecific binding was determined in the presence of 1 uM Bv8. Displacement curves were determined in triplicate. The inhibition constant (Ki) of th...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM26336(6-[(2-aminoethyl)amino]-3-[(4-ethylphenyl)methyl]-...)
Affinity DataKi:  440nM ΔG°:  -37.7kJ/molepH: 7.4 T: 2°CAssay Description:Nonspecific binding was determined in the presence of 1 uM Bv8. Displacement curves were determined in triplicate. The inhibition constant (Ki) of th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM26337(6-{[2-(4,5-dihydro-1H-imidazol-2-ylamino)ethyl]ami...)
Affinity DataKi:  4.72E+3nM ΔG°:  -31.6kJ/molepH: 7.4 T: 2°CAssay Description:Nonspecific binding was determined in the presence of 1 uM Bv8. Displacement curves were determined in triplicate. The inhibition constant (Ki) of th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250600(US10167273, Example 79 | US10544126, Example 79 | ...)
Affinity DataIC50:  50nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250620(US10167273, Example 99 | US10544126, Example 99 | ...)
Affinity DataIC50:  60nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250599(US10167273, Example 78 | US10544126, Example 78 | ...)
Affinity DataIC50:  70nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250617(US10167273, Example 98 | US10544126, Example 96 | ...)
Affinity DataIC50:  80nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250612(US10167273, Example 91 | US10544126, Example 91 | ...)
Affinity DataIC50:  140nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250617(US10167273, Example 98 | US10544126, Example 96 | ...)
Affinity DataIC50:  160nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250595(US10167273, Example 74 | US10544126, Example 74 | ...)
Affinity DataIC50:  170nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250611(US10167273, Example 90 | US10544126, Example 90 | ...)
Affinity DataIC50:  170nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250609(US10167273, Example 88 | US10544126, Example 88 | ...)
Affinity DataIC50:  200nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250594(US10167273, Example 73 | US10544126, Example 73 | ...)
Affinity DataIC50:  200nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250560(US10167273, Example 39 | US10544126, Example 39 | ...)
Affinity DataIC50:  210nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250561(US10167273, Example 40 | US10544126, Example 40 | ...)
Affinity DataIC50:  210nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250544(US10167273, Example 23 | US10544126, Example 23 | ...)
Affinity DataIC50:  220nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250555(US10167273, Example 34 | US10544126, Example 34 | ...)
Affinity DataIC50:  240nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250552(US10167273, Example 31 | US10544126, Example 31 | ...)
Affinity DataIC50:  310nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250626(US10167273, Example 107 | US10544126, Example 107 ...)
Affinity DataIC50:  310nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250549(US10167273, Example 28 | US10544126, Example 28 | ...)
Affinity DataIC50:  320nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250632(US10167273, Example 111 | US10544126, Example 111 ...)
Affinity DataIC50:  340nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250610(US10167273, Example 89 | US10544126, Example 89 | ...)
Affinity DataIC50:  410nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250626(US10167273, Example 107 | US10544126, Example 107 ...)
Affinity DataIC50:  410nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250593(US10167273, Example 72 | US10544126, Example 72 | ...)
Affinity DataIC50:  440nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250554(US10167273, Example 33 | US10544126, Example 33 | ...)
Affinity DataIC50:  440nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250623(US10167273, Example 102 | US10544126, Example 102 ...)
Affinity DataIC50:  470nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250535(US10167273, Example 14 | US10544126, Example 14 | ...)
Affinity DataIC50:  470nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250551(US10167273, Example 30 | US10544126, Example 30 | ...)
Affinity DataIC50:  510nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250576(US10167273, Example 55 | US10544126, Example 55 | ...)
Affinity DataIC50:  520nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250588(US10167273, Example 67 | US10544126, Example 67 | ...)
Affinity DataIC50:  520nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250526(US10167273, Example 5 | US10544126, Example 5 | US...)
Affinity DataIC50:  530nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250614(US10167273, Example 93 | US10544126, Example 93 | ...)
Affinity DataIC50:  610nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250584(US10167273, Example 63 | US10544126, Example 63 | ...)
Affinity DataIC50:  640nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250602(US10167273, Example 81 | US10544126, Example 81 | ...)
Affinity DataIC50:  670nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250583(US10167273, Example 62 | US10544126, Example 62 | ...)
Affinity DataIC50:  680nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250616(US10167273, Example 95 | US10544126, Example 95 | ...)
Affinity DataIC50:  710nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250625(US10167273, Example 104 | US10544126, Example 104 ...)
Affinity DataIC50:  720nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250605(US10167273, Example 84 | US10544126, Example 84 | ...)
Affinity DataIC50:  720nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250604(US10167273, Example 83 | US10544126, Example 83 | ...)
Affinity DataIC50:  730nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250592(US10167273, Example 71 | US10544126, Example 71 | ...)
Affinity DataIC50:  780nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250534(US10167273, Example 13 | US10544126, Example 13 | ...)
Affinity DataIC50:  790nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250601(US10167273, Example 80 | US10544126, Example 80 | ...)
Affinity DataIC50:  810nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250525(US10167273, Example 4 | US10544126, Example 4 | US...)
Affinity DataIC50:  820nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250532(US10167273, Example 11 | US10544126, Example 11 | ...)
Affinity DataIC50:  860nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250585(US10167273, Example 64 | US10544126, Example 64 | ...)
Affinity DataIC50:  890nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250581(US10167273, Example 60 | US10544126, Example 60 | ...)
Affinity DataIC50:  900nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250574(US10167273, Example 53 | US10544126, Example 53 | ...)
Affinity DataIC50:  900nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250586(US10167273, Example 65 | US10544126, Example 65 | ...)
Affinity DataIC50:  940nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250577(US10167273, Example 56 | US10544126, Example 56 | ...)
Affinity DataIC50:  950nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250567(US10167273, Example 46 | US10544126, Example 46 | ...)
Affinity DataIC50:  1.00E+3nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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