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Found 33 of ph data with Target = 'Sterol 14-alpha demethylase'
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM25810(2-phenyl-N-(pyridin-4-yl)butanamide | 2-phenyl-N-p...)
Affinity DataKd:  440nMpH: 7.4 T: 2°CAssay Description:As a cysteine-coordinated hemoprotein, sterol 14-alpha-demethylase responds spectrally to any perturbations in the area surrounding the heme iron. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM213825(VNI)
Affinity DataKd:  15nMpH: 7.4 T: 2°CAssay Description:Briefly, the reaction mixture contained 1 uM CYP51, 2 uM cytochrome P450 reductase, 100 uM dilauroyl-alpha-phosphatidylcholine, 0.4 mg/ml isoctrate d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM29342(ChemDiv C155-0123, 9)
Affinity DataKd:  240nMpH: 7.4 T: 2°CAssay Description:As a cysteine-coordinated hemoprotein, sterol 14-alpha-demethylase responds spectrally to any perturbations in the area surrounding the heme iron. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM22962(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataKd:  290nMpH: 7.4 T: 2°CAssay Description:As a cysteine-coordinated hemoprotein, sterol 14-alpha-demethylase responds spectrally to any perturbations in the area surrounding the heme iron. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM29343(Indomethacin-amide derivative, 13)
Affinity DataKd:  7.60E+3nMpH: 7.4 T: 2°CAssay Description:As a cysteine-coordinated hemoprotein, sterol 14-alpha-demethylase responds spectrally to any perturbations in the area surrounding the heme iron. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM29344(Indomethacin-amide derivative, 14)
Affinity DataKd:  540nMpH: 7.4 T: 2°CAssay Description:As a cysteine-coordinated hemoprotein, sterol 14-alpha-demethylase responds spectrally to any perturbations in the area surrounding the heme iron. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM29345(Indomethacin-amide derivative, 15)
Affinity DataKd:  370nMpH: 7.4 T: 2°CAssay Description:As a cysteine-coordinated hemoprotein, sterol 14-alpha-demethylase responds spectrally to any perturbations in the area surrounding the heme iron. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM29346(Indomethacin-amide derivative, 16)
Affinity DataKd:  3.30E+3nMpH: 7.4 T: 2°CAssay Description:As a cysteine-coordinated hemoprotein, sterol 14-alpha-demethylase responds spectrally to any perturbations in the area surrounding the heme iron. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM29347(Indomethacin-amide derivative, 19)
Affinity DataKd:  560nMpH: 7.4 T: 2°CAssay Description:As a cysteine-coordinated hemoprotein, sterol 14-alpha-demethylase responds spectrally to any perturbations in the area surrounding the heme iron. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM29348(Indomethacin-amide derivative, 18)
Affinity DataKd:  260nMpH: 7.4 T: 2°CAssay Description:As a cysteine-coordinated hemoprotein, sterol 14-alpha-demethylase responds spectrally to any perturbations in the area surrounding the heme iron. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM29349(Indomethacin-amide derivative, 20)
Affinity DataKd:  2.31E+3nMpH: 7.4 T: 2°CAssay Description:As a cysteine-coordinated hemoprotein, sterol 14-alpha-demethylase responds spectrally to any perturbations in the area surrounding the heme iron. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM29350(Indomethacin-amide derivative, 21)
Affinity DataKd:  360nMpH: 7.4 T: 2°CAssay Description:As a cysteine-coordinated hemoprotein, sterol 14-alpha-demethylase responds spectrally to any perturbations in the area surrounding the heme iron. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM29351(Indomethacin-amide derivative, 22)
Affinity DataKd:  150nMpH: 7.4 T: 2°CAssay Description:As a cysteine-coordinated hemoprotein, sterol 14-alpha-demethylase responds spectrally to any perturbations in the area surrounding the heme iron. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM81297(Azole, 1)
Affinity DataKd:  320nMpH: 6.0Assay Description:Azole derivatives used as an inhibitor of TB and TC CYP51.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM81310(Azole, 3)
Affinity DataKd:  140nMpH: 6.0Assay Description:Azole derivatives used as an inhibitor of TB and TC CYP51.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM81299(Azole, 4)
Affinity DataKd:  70nMpH: 6.0Assay Description:Azole derivatives used as an inhibitor of TB and TC CYP51.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM81300(Azole, 5)
Affinity DataKd:  1.20E+3nMpH: 6.0Assay Description:Azole derivatives used as an inhibitor of TB and TC CYP51.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM81301(Azole, 6)
Affinity DataKd:  130nMpH: 6.0Assay Description:Azole derivatives used as an inhibitor of TB and TC CYP51.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM81302(Azole, 7)
Affinity DataKd:  380nMpH: 6.0Assay Description:Azole derivatives used as an inhibitor of TB and TC CYP51.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM81303(Azole, 8)
Affinity DataKd:  110nMpH: 6.0Assay Description:Azole derivatives used as an inhibitor of TB and TC CYP51.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM81304(Azole, 9)
Affinity DataKd:  90nMpH: 6.0Assay Description:Azole derivatives used as an inhibitor of TB and TC CYP51.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM81305(Azole, 10)
Affinity DataKd:  50nMpH: 6.0Assay Description:Azole derivatives used as an inhibitor of TB and TC CYP51.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM81306(Azole, 11)
Affinity DataKd:  110nMpH: 6.0Assay Description:Azole derivatives used as an inhibitor of TB and TC CYP51.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM8610(1-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imi...)
Affinity DataKd:  20nMpH: 6.0Assay Description:Azole derivatives used as an inhibitor of TB and TC CYP51.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM25817(2-(2,4-difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-...)
Affinity DataKd:  230nMpH: 6.0Assay Description:Azole derivatives used as an inhibitor of TB and TC CYP51.More data for this Ligand-Target Pair
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM50214606(4'-chloro-biphenyl-4-carboxylic acid (2-imidazol-1...)
Affinity DataKd:  70nMpH: 6.0Assay Description:Azole derivatives used as an inhibitor of TB and TC CYP51.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM81307(Azole, 19)
Affinity DataKd:  60nMpH: 6.0Assay Description:Azole derivatives used as an inhibitor of TB and TC CYP51.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM81308(Azole, 20)
Affinity DataKd:  70nMpH: 6.0Assay Description:Azole derivatives used as an inhibitor of TB and TC CYP51.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM81309(Azole, 17)
Affinity DataKd:  110nMpH: 6.0Assay Description:Azole derivatives used as an inhibitor of TB and TC CYP51.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM213823(EPL-BS1246 (UDO))
Affinity DataKd:  19nMpH: 7.4 T: 2°CAssay Description:Briefly, the reaction mixture contained 1 uM CYP51, 2 uM cytochrome P450 reductase, 100 uM dilauroyl-alpha-phosphatidylcholine, 0.4 mg/ml isoctrate d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM213822(EPL-BS0967 (UDD))
Affinity DataKd:  32nMpH: 7.4 T: 2°CAssay Description:Briefly, the reaction mixture contained 1 uM CYP51, 2 uM cytochrome P450 reductase, 100 uM dilauroyl-alpha-phosphatidylcholine, 0.4 mg/ml isoctrate d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM213824(Posaconazole)
Affinity DataKd:  18nMpH: 7.4 T: 2°CAssay Description:Briefly, the reaction mixture contained 1 uM CYP51, 2 uM cytochrome P450 reductase, 100 uM dilauroyl-alpha-phosphatidylcholine, 0.4 mg/ml isoctrate d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM29341(ChemDiv 5556-0480, 7)
Affinity DataKd:  750nMpH: 7.4 T: 2°CAssay Description:As a cysteine-coordinated hemoprotein, sterol 14-alpha-demethylase responds spectrally to any perturbations in the area surrounding the heme iron. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed