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Found 9 of ph data with Target = 'Telomerase protein component 1'
TargetTelomerase protein component 1(Homo sapiens (Human))
Geron

US Patent
LigandPNGBDBM279791(PMPG free acid, R form | US10035814, Compound 1426...)
Affinity DataEC50:  850nMpH: 8.5Assay Description:(((Guanine-9-yl) propan-2-oxy) methyl) phosphonic acid diphosphate (PMPGpp) acts as a chain terminator and competes with dGTP.Purified human telomera...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetTelomerase protein component 1(Homo sapiens (Human))
Geron

US Patent
LigandPNGBDBM279792(6-thio-G- phosphonate (6-S-PMPG), R form | US10035...)
Affinity DataEC50:  1.35E+4nMpH: 8.5Assay Description:(((Guanine-9-yl) propan-2-oxy) methyl) phosphonic acid diphosphate (PMPGpp) acts as a chain terminator and competes with dGTP.Purified human telomera...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetTelomerase protein component 1(Homo sapiens (Human))
Geron

US Patent
LigandPNGBDBM279793(PMPG(lin) | US10035814, Compound 142848)
Affinity DataEC50:  1.50E+3nMpH: 8.5Assay Description:(((Guanine-9-yl) propan-2-oxy) methyl) phosphonic acid diphosphate (PMPGpp) acts as a chain terminator and competes with dGTP.Purified human telomera...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetTelomerase protein component 1(Homo sapiens (Human))
Geron

US Patent
LigandPNGBDBM279794(PM(3)BG | US10035814, Compound 142916)
Affinity DataEC50:  1.00E+4nMpH: 8.5Assay Description:(((Guanine-9-yl) propan-2-oxy) methyl) phosphonic acid diphosphate (PMPGpp) acts as a chain terminator and competes with dGTP.Purified human telomera...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetTelomerase protein component 1(Homo sapiens (Human))
Geron

US Patent
LigandPNGBDBM279799(PMP(2)G | US10035814, Compound 142879)
Affinity DataEC50:  3.10E+3nMpH: 8.5Assay Description:(((Guanine-9-yl) propan-2-oxy) methyl) phosphonic acid diphosphate (PMPGpp) acts as a chain terminator and competes with dGTP.Purified human telomera...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetTelomerase protein component 1(Homo sapiens (Human))
Geron

US Patent
LigandPNGBDBM279796(FPMPG | US10035814, Compound 142856)
Affinity DataEC50:  7.50E+3nMpH: 8.5Assay Description:(((Guanine-9-yl) propan-2-oxy) methyl) phosphonic acid diphosphate (PMPGpp) acts as a chain terminator and competes with dGTP.Purified human telomera...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetTelomerase protein component 1(Homo sapiens (Human))
Geron

US Patent
LigandPNGBDBM279797(PMIBeG, free acid | US10035814, Compound 142810)
Affinity DataEC50:  1.40E+3nMpH: 8.5Assay Description:(((Guanine-9-yl) propan-2-oxy) methyl) phosphonic acid diphosphate (PMPGpp) acts as a chain terminator and competes with dGTP.Purified human telomera...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetTelomerase protein component 1(Homo sapiens (Human))
Geron

US Patent
LigandPNGBDBM279798(PMIBaG (mix R,S) | US10035814, Compound 142846)
Affinity DataEC50:  4.40E+3nMpH: 8.5Assay Description:(((Guanine-9-yl) propan-2-oxy) methyl) phosphonic acid diphosphate (PMPGpp) acts as a chain terminator and competes with dGTP.Purified human telomera...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetTelomerase protein component 1(Homo sapiens (Human))
Geron

US Patent
LigandPNGBDBM279795(PM(2)BG | US10035814, Compound 142915)
Affinity DataEC50: >6.00E+4nMpH: 8.5Assay Description:(((Guanine-9-yl) propan-2-oxy) methyl) phosphonic acid diphosphate (PMPGpp) acts as a chain terminator and competes with dGTP.Purified human telomera...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent