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Found 4 of ph data with Target = 'Tyrosine-protein kinase Lyn'
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Pharmacyclics

US Patent
LigandPNGBDBM1773(US10280174, Comparative Compound 1 | US8476284, 4 ...)
Affinity DataKi:  14nMpH: 7.4Assay Description:Btk kinase activity was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Pharmacyclics

US Patent
LigandPNGBDBM50430875(CHEMBL2336005 | US9062066, LCB 03-0110)
Affinity DataIC50:  2.30nMpH: 8.0Assay Description:The inhibitory activity measurement against the kinases mentioned above was measured in the kinase inhibition reaction mixture containing 2 ul purifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Pharmacyclics

US Patent
LigandPNGBDBM50430875(CHEMBL2336005 | US9062066, LCB 03-0110)
Affinity DataIC50:  4.30nMpH: 8.0Assay Description:The inhibitory activity measurement against the kinases mentioned above was measured in the kinase inhibition reaction mixture containing 2 ul purifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Pharmacyclics

US Patent
LigandPNGBDBM236557(US9365572, 5)
Affinity DataIC50:  1.37E+3nMpH: 7.5 T: 2°CAssay Description:Agents: 1-fold kinase buffer without MnCl2: 50 mM HEPES, pH 7.5, 0.0015% Brij-35, 10 mM MgCl2, 2 mM DTT. 1-fold kinase buffer with MnCl2: 50 mM HEPES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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