Affinity DataKi: 103nM ΔG°: -39.5kJ/molepH: 8.0 T: 2°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: 113nM ΔG°: -39.3kJ/molepH: 8.0 T: 2°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: 126nM ΔG°: -39.0kJ/molepH: 8.0 T: 2°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: 137nM ΔG°: -38.8kJ/molepH: 8.0 T: 2°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: 147nM ΔG°: -38.6kJ/molepH: 8.0 T: 2°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: 155nM ΔG°: -38.5kJ/molepH: 8.0 T: 2°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: 166nM ΔG°: -38.3kJ/molepH: 8.0 T: 2°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: 175nM ΔG°: -38.2kJ/molepH: 8.0 T: 2°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: 175nM ΔG°: -38.2kJ/molepH: 8.0 T: 2°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: 179nM ΔG°: -38.1kJ/molepH: 8.0 T: 2°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: 206nM ΔG°: -37.8kJ/molepH: 8.0 T: 2°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: 208nM ΔG°: -37.8kJ/molepH: 8.0 T: 2°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: 223nM ΔG°: -37.6kJ/molepH: 8.0 T: 2°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: 225nM ΔG°: -37.6kJ/molepH: 8.0 T: 2°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: 236nM ΔG°: -37.4kJ/molepH: 8.0 T: 2°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: 244nM ΔG°: -37.4kJ/molepH: 8.0 T: 2°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: 271nM ΔG°: -37.1kJ/molepH: 8.0 T: 2°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: 309nM ΔG°: -36.8kJ/molepH: 8.0 T: 2°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: 405nM ΔG°: -36.1kJ/molepH: 8.0 T: 2°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: 415nM ΔG°: -36.1kJ/molepH: 8.0 T: 2°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nM ΔG°: >-35.3kJ/molepH: 8.0 T: 2°CAssay Description:The samples were assayed in a solution composed of PDE4, [3H]cAMP/cAMP, and test compounds. To convert AMP to adenosine, snake venom was added to eac...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nM ΔG°: >-35.3kJ/molepH: 8.0 T: 2°CAssay Description:The samples were assayed in a solution composed of PDE4, [3H]cAMP/cAMP, and test compounds. To convert AMP to adenosine, snake venom was added to eac...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nM ΔG°: >-35.3kJ/molepH: 8.0 T: 2°CAssay Description:The samples were assayed in a solution composed of PDE4, [3H]cAMP/cAMP, and test compounds. To convert AMP to adenosine, snake venom was added to eac...More data for this Ligand-Target Pair
Affinity DataKi: 1.19E+3nM ΔG°: -33.5kJ/molepH: 8.0 T: 2°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: 3.39E+3nM ΔG°: -30.9kJ/molepH: 8.0 T: 2°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: 3.90E+3nM ΔG°: -30.6kJ/molepH: 8.0 T: 2°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: 5.20E+3nM ΔG°: -29.9kJ/molepH: 8.0 T: 2°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: 7.94E+3nM ΔG°: -28.8kJ/molepH: 8.0 T: 2°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: 1.52E+4nM ΔG°: -27.2kJ/molepH: 8.0 T: 2°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nM ΔG°: >-24.3kJ/molepH: 8.0 T: 2°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nM ΔG°: >-24.3kJ/molepH: 8.0 T: 2°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nM ΔG°: >-24.3kJ/molepH: 8.0 T: 2°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.25nMpH: 7.5 T: 2°CAssay Description:Inhibition of the human PDE4 enzyme, using semi-purified enzyme from human U937 cells. The PDE4 enzyme was partially purified from human U937 myeloid...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:PDE4 catalytic activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using PDE-SPA kit (Amersham International). [3H]-AMP was c...More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMpH: 7.5 T: 2°CAssay Description:Inhibition of the human PDE4 enzyme, using semi-purified enzyme from human U937 cells. The PDE4 enzyme was partially purified from human U937 myeloid...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMpH: 7.5 T: 2°CAssay Description:Inhibition of the human PDE4 enzyme, using semi-purified enzyme from human U937 cells. The PDE4 enzyme was partially purified from human U937 myeloid...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMpH: 7.5 T: 2°CAssay Description:Inhibition of the human PDE4 enzyme, using semi-purified enzyme from human U937 cells. The PDE4 enzyme was partially purified from human U937 myeloid...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMpH: 7.5 T: 2°CAssay Description:Inhibition of the human PDE4 enzyme, using semi-purified enzyme from human U937 cells. The PDE4 enzyme was partially purified from human U937 myeloid...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMpH: 7.5 T: 2°CAssay Description:Inhibition of the human PDE4 enzyme, using semi-purified enzyme from human U937 cells. The PDE4 enzyme was partially purified from human U937 myeloid...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:Inhibition of the human PDE4 enzyme, using semi-purified enzyme from human U937 cells. The PDE4 enzyme was partially purified from human U937 myeloid...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMpH: 7.5 T: 2°CAssay Description:Inhibition of the human PDE4 enzyme, using semi-purified enzyme from human U937 cells. The PDE4 enzyme was partially purified from human U937 myeloid...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMpH: 7.5 T: 2°CAssay Description:Inhibition of the human PDE4 enzyme, using semi-purified enzyme from human U937 cells. The PDE4 enzyme was partially purified from human U937 myeloid...More data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMpH: 7.5 T: 2°CAssay Description:Inhibition of the human PDE4 enzyme, using semi-purified enzyme from human U937 cells. The PDE4 enzyme was partially purified from human U937 myeloid...More data for this Ligand-Target Pair
Affinity DataIC50: 6.70nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair
Affinity DataIC50: 6.70nMpH: 7.2 T: 2°CAssay Description:Inhibition of PDE4A was performed using IMAP technology (Molecular Devices, CA). PDE4A1A mixture was dispensed into 1536-well black/solid bottom assa...More data for this Ligand-Target Pair