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Found 12 of affinity data with PDB=1LJT
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

US Patent
LigandPNGBDBM50186426(CHEMBL210858 | US10336721, ISO-1 | US10968198, ISO...)
Affinity DataKi:  2.10E+4nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using 4-hydroxyphenyl pyruvic acid (HPP) as substrate, largely following previously report...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

US Patent
LigandPNGBDBM50186426(CHEMBL210858 | US10336721, ISO-1 | US10968198, ISO...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of recombinant MIF (unknown origin) tautomerase activity using dopachrome methyl ester as substrate measured for 2 to 20 secs by spectroph...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

US Patent
LigandPNGBDBM50186434((R)-methyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxa...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human recombinant MIF tautomeraseMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

US Patent
LigandPNGBDBM50186434((R)-methyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxa...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of MIF tautomerase activityMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Mus musculus (Mouse))
The Feinstein Institute For Medical Research

US Patent
LigandPNGBDBM50186426(CHEMBL210858 | US10336721, ISO-1 | US10968198, ISO...)
Affinity DataIC50:  1.10E+4nMpH: 7.2 T: 2°CAssay Description:MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

US Patent
LigandPNGBDBM50186426(CHEMBL210858 | US10336721, ISO-1 | US10968198, ISO...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of MIF tautomerase activityMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

US Patent
LigandPNGBDBM50186434((R)-methyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxa...)
Affinity DataIC50:  1.44E+4nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli using L-dopachrome methyl ester as substrate incubated for 30 ...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

US Patent
LigandPNGBDBM50186426(CHEMBL210858 | US10336721, ISO-1 | US10968198, ISO...)
Affinity DataIC50:  1.82E+4nMAssay Description:Inhibition of recombinant human MIF (Pro2 to Ala115 residues) expressed in Escherichia coli using dopachrome methyl ester as substrate preincubated w...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

US Patent
LigandPNGBDBM50186426(CHEMBL210858 | US10336721, ISO-1 | US10968198, ISO...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of spontaneous secretion/release/recognition of MIF from freshly isolated human PBMC by ELISAMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

US Patent
LigandPNGBDBM50186426(CHEMBL210858 | US10336721, ISO-1 | US10968198, ISO...)
Affinity DataIC50:  6.90E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of MIF in human THP1 cellsMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

US Patent
LigandPNGBDBM50186426(CHEMBL210858 | US10336721, ISO-1 | US10968198, ISO...)
Affinity DataIC50:  7.90E+4nMAssay Description:Inhibition of recombinant His-tagged MIF tautomerase activity (unknown origin) using 4-HPP as substrateMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

US Patent
LigandPNGBDBM50186426(CHEMBL210858 | US10336721, ISO-1 | US10968198, ISO...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of dopachrome tautomerase activity of human recombinant MIFMore data for this Ligand-Target Pair