Compile Data Set for Download or QSAR
maximum 50k data
Found 3 of affinity data with PDB=2XFI
TargetBeta-secretase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322877(CHEMBL1210329 | N-((1S,2R)-3-(((1S)-2-(CYCLOHEXYLA...)
Affinity DataIC50:  15nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322877(CHEMBL1210329 | N-((1S,2R)-3-(((1S)-2-(CYCLOHEXYLA...)
Affinity DataIC50:  510nMAssay Description:Inhibition of BACE1 assessed as inhibition of amyloid beta-42 production by cell based assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322877(CHEMBL1210329 | N-((1S,2R)-3-(((1S)-2-(CYCLOHEXYLA...)
Affinity DataIC50:  570nMAssay Description:Inhibition of BACE1 assessed as inhibition of amyloid beta-40 production by cell based assayMore data for this Ligand-Target Pair