Affinity DataIC50: 15.5nMAssay Description:Displacement of tetra-acetylated H4 peptide from human Brd4 bromodomain BD12 after 1 hr by FRET analysisMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 15.5nMAssay Description:Displacement of acetylated histone peptide from BRD4-BD1,2 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of His6-tagged BRD4-BD12 expressed in Escherichia coli assessed as inhibition of binding to SGRG-K(Ac)-GG-K(Ac)-GLG-K(Ac)-GGA-K(Ac)-RHGSGS...More data for this Ligand-Target Pair
Affinity DataIC50: 470nMAssay Description:Inhibition of His6-tagged BRD4 expressed in Escherichia coli after 60 mins by fluorescence anisotropy assayMore data for this Ligand-Target Pair
Affinity DataIC50: 501nMAssay Description:Binding affinity to His6-tagged BRD4 (unknown origin) after 60 mins by fluorescence anisotropy binding AssayMore data for this Ligand-Target Pair
Affinity DataKd: 24nMAssay Description:Binding affinity to His6-tagged BRD4 expressed in Escherichia coli by isothermal colorimetric analysisMore data for this Ligand-Target Pair
Affinity DataKd: 19nMAssay Description:Binding affinity to N-terminal portion of human Brd4 containing bromodomain BD12 expressed in Escherichia coli by isothermal titration calorimetric a...More data for this Ligand-Target Pair
Affinity DataKd: 19nMAssay Description:Binding affinity to BRD4 by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 52.5nMAssay Description:Binding affinity to BRD4-BD1,2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
