Compile Data Set for Download or QSAR
maximum 50k data
Found 4 of affinity data with PDB=3FLI
TargetBile acid receptor(Homo sapiens (Human))
Exelixis

LigandPNGBDBM28542(WAY-362450 | XL335 | propan-2-yl 3-[(3,4-difluorop...)
Affinity DataEC50:  4nMpH: 7.0 T: 2°CAssay Description:The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Exelixis

LigandPNGBDBM28542(WAY-362450 | XL335 | propan-2-yl 3-[(3,4-difluorop...)
Affinity DataEC50:  15nMAssay Description:Agonist activity at human FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM28542(WAY-362450 | XL335 | propan-2-yl 3-[(3,4-difluorop...)
Affinity DataEC50:  152nMAssay Description:Agonist activity at mouse FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Exelixis

LigandPNGBDBM28542(WAY-362450 | XL335 | propan-2-yl 3-[(3,4-difluorop...)
Affinity DataEC50:  16nMAssay Description:Agonist activity at gal4-tagged human FXR-ligand binding domain expressed in human HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair