Affinity DataKi: 60nMAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
Affinity DataKi: 95nM ΔG°: -40.1kJ/molepH: 8.0 T: 2°CAssay Description:The testing for the inhibition activities of imidazole derivatives and cacodylate on gQC and sQC was evaluated at 25 C using the fluorescent substrat...More data for this Ligand-Target Pair
Affinity DataKi: 1.82E+3nM ΔG°: -32.8kJ/molepH: 8.0 T: 2°CAssay Description:The testing for the inhibition activities of imidazole derivatives and cacodylate on gQC and sQC was evaluated at 25 C using the fluorescent substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human recombinant glutaminyl cyclase expressed in Escherichia coli using H-Gln-Gln-H substrate measured for 15 mins by spectrophotometr...More data for this Ligand-Target Pair