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Found 14 of affinity data with PDB=4NR7
TargetCREB-binding protein(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM188519(SGC-CBP30)
Affinity DataIC50:  30nMAssay Description:Displacement of biotinylated ligand from CBP (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM188519(SGC-CBP30)
Affinity DataIC50:  64nMAssay Description:Inhibition of human CREBBP by FRET assayMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM188519(SGC-CBP30)
Affinity DataIC50:  69nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from human his-tagged CBP by alphascreen assayMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM188519(SGC-CBP30)
Affinity DataIC50:  79nMAssay Description:Inhibition of human CREBBP by AlphaScreen assayMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM188519(SGC-CBP30)
Affinity DataIC50:  80nMAssay Description:Inhibition of biotinylated-H4KAc4 binding to human His6-tagged CBP (R1081 to G1197 residues) expressed in Escherichia coli BL21(DE3) after 2.5 hrs by...More data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM188519(SGC-CBP30)
Affinity DataIC50:  125nMAssay Description:Inhibition of His6-tagged human CREBBP (R1081 to G1197 residues) expressed in Escherichia coli BL21(DE3) using biotinylated-H4KAc4 as substrate by Al...More data for this Ligand-Target Pair
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM188519(SGC-CBP30)
Affinity DataIC50:  230nMAssay Description:Inhibition of biotinylated-H4KAc4 binding to human His6-tagged EP300 (A1040 to G1161 residues) expressed in Escherichia coli BL21(DE3) after 2.5 hrs ...More data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM188519(SGC-CBP30)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of Halo-tagged histone H3.3 binding to NanoLuc luciferase conjugated CBP (unknown origin) expressed in HEK293 cells after overnight incuba...More data for this Ligand-Target Pair
TargetCREB-binding protein/Histone acetyltransferase p300(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM188519(SGC-CBP30)
Affinity DataEC50:  6.90E+3nMAssay Description:Inhibition of CBP/EP300 (unknown origin) assessed as reduction in MYC expression by cell based assayMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM188519(SGC-CBP30)
Affinity DataKd:  21nMAssay Description:Binding affinity to human CBP by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM188519(SGC-CBP30)
Affinity DataKd:  21nMAssay Description:Binding affinity to human CBP by ITC analysisMore data for this Ligand-Target Pair
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM188519(SGC-CBP30)
Affinity DataKd:  32nMAssay Description:Binding affinity to human p300 by ITC analysisMore data for this Ligand-Target Pair
TargetCREB-binding protein(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM188519(SGC-CBP30)
Affinity DataKd:  21nMAssay Description:Experiments were performed using recombinant CBP and BRD4 bromodomainsusing the procedure reported recently (Hett et al., 2015).More data for this Ligand-Target Pair
TargetCREB-binding protein/Histone acetyltransferase p300(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM188519(SGC-CBP30)
Affinity DataKd:  21nMAssay Description:Binding affinity to human N-terminal His10-tagged/C-terminal Biotin-tagged CBP (R1081 to G1198 residues)/P300 expressed in Escherichia coli BL21(DE3)...More data for this Ligand-Target Pair