Affinity DataKi: 9.80nMAssay Description:Inhibition of human CYP2D6 by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Binding affinity for cytochrome P450 2D6More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant microsomal CYP2D6 using {3-[2-(N,N-diethyl-N-methylamino)ethyl]-7-methoxy-4-methylcoumarin} as substrate assessed as ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of MAMC O-dealkylation mediated by human Cytochrome P450 2D6 expressed in human lymphoblastoid cell lineMore data for this Ligand-Target Pair
Affinity DataIC50: <6nMAssay Description:Inhibition of CYP2D6 in human liver microsomeMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate after 10 mins by LC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of CYP2D6 after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant CYP2D6 expressed in insect microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human CYP2D6 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant CYP2D6 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant CYP2D6 using MFC as substrate incubated for 40 mins by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human CYP2D6 expressed in baculovirus-infected insect cell systemMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of CYP2D6 in human liver microsomes assessed as dextromethorphan O-demethylation after 4 to 40 mins in presence of NADPH by LCMS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of CYP2D6 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using bufuralol as substrate after 5 to 15 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of CYP2D6 in pooled human hepatic microsomes using dextromethorphan substrate in presence of NADPHMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human CYP2D6 by P450-Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 78nMAssay Description:Inhibition of human CYP2D6 by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 82nMAssay Description:Inhibition of human liver microsome CYP2D6 in assessed as [14C]formaldehyde formationMore data for this Ligand-Target Pair
Affinity DataIC50: 118nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate preincubated for 10 mins followed by NADPH addition measured after...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of CYP2D6 (unknown origin) using AMMC by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 135nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate preincubated for 10 mins followed by NADPH addition measured after...More data for this Ligand-Target Pair
Affinity DataIC50: 151nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate preincubated for 10 mins followed by NADPH addition measured after...More data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate upto 10 uM after 20 mins in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human recombinant CYP2D6 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair