Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compound at vario...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 17nMpH: 7.5 T: 2°CAssay Description:Briefly, recombinant human or murine FD catalytic domain (10 nM concentration) were incubated with compound at various concentrations for 1 h at room...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMpH: 7.4 T: 2°CAssay Description:Recombinant human FD (10 nM concentration) was incubated with compound
at various concentrations for 1 h at room temperature in 0.1 M PBS (pH
7.4) ...More data for this Ligand-Target Pair
Affinity DataKd: 6.03nMpH: 7.4 T: 2°CAssay Description:Single cycle kinetics (SCK): five increasing concentrations were injected successively without allowing for the dissociation of the protein-ligand co...More data for this Ligand-Target Pair
Affinity DataKd: 6.55nMpH: 7.4 T: 2°CAssay Description:Standard kinetics: an independent association-dissociation cycle was run for each concentration by injecting compound solution and waiting for dissoc...More data for this Ligand-Target Pair
