Compile Data Set for Download or QSAR
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Found 14 of affinity data with PDB=5JNA
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of truncated human cloned membrane-associated carbonic anhydrase 4 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of human recombinant CA4 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of human carbonic anhydrase 4More data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)
Affinity DataKi:  4.90E+3nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of human recombinant CA4 after 15 mins by CO2 hydration stopped flow assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibitory activity against human carbonic anhydrase IV (hCAIV)More data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of full length human carbonic anhydrase 4 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)
Affinity DataKi:  4.90E+3nM ΔG°:  -30.3kJ/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM50159793(CHEMBL1354 | Natriumazetat | SODIUM ACETATE ANHYDR...)
Affinity DataKi:  5.50E+5nMAssay Description:Binding affinity against human cytosolic Carbonic anhydrase IVMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM26992(CHEMBL183495 | SO4(2-) | SODIUM SULFATE | sulfate ...)
Affinity DataKi:  9.00E+6nMAssay Description:Inhibition constant of anion against human carbonic anhydrase isozyme hCA IVMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM26992(CHEMBL183495 | SO4(2-) | SODIUM SULFATE | sulfate ...)
Affinity DataKi:  9.00E+6nMAssay Description:Inhibitory activity against human Carbonic anhydrase IVMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM26992(CHEMBL183495 | SO4(2-) | SODIUM SULFATE | sulfate ...)
Affinity DataKi:  9.00E+6nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM26992(CHEMBL183495 | SO4(2-) | SODIUM SULFATE | sulfate ...)
Affinity DataKi:  9.00E+6nMAssay Description:Inhibition of human carbonic anhydrase 4 by Lineweaver-Burk curvesMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM26992(CHEMBL183495 | SO4(2-) | SODIUM SULFATE | sulfate ...)
Affinity DataKi:  4.40E+7nMAssay Description:Inhibitory constant against carbonic anhydrase IVMore data for this Ligand-Target Pair