Compile Data Set for Download or QSAR
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Found 10 of affinity data with PDB=6GDC
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Union Life Sciences

Curated by ChEMBL
LigandPNGBDBM12414(CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...)
Affinity DataKi:  305nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Union Life Sciences

Curated by ChEMBL
LigandPNGBDBM12414(CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...)
Affinity DataKi:  430nMAssay Description:Inhibition of human carbonic anhydrase 2 esterase activity using 4-nitrophenylacetate as substrateMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Union Life Sciences

Curated by ChEMBL
LigandPNGBDBM12414(CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of cytosolic carbonic anhydrase 2 esterase activity isolated from human serum using 4-nitrophenylacetate as substrate measured over 3 mins...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Union Life Sciences

Curated by ChEMBL
LigandPNGBDBM12414(CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...)
Affinity DataKi:  1.10E+3nM ΔG°:  -34.0kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Union Life Sciences

Curated by ChEMBL
LigandPNGBDBM12414(CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...)
Affinity DataKi:  5.87E+3nMAssay Description:Inhibition of human esterase activity of carbonic anhydrase 2 using 4-nitrophenylacetate as substrate after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 1/2/5B, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM12414(CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro inhibition of crude dog red blood cell carbonic anhydraseMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Union Life Sciences

Curated by ChEMBL
LigandPNGBDBM12414(CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...)
Affinity DataKd:  1.14E+6nMAssay Description:Binding affinity to GST-fused human carbonic anhydrase-2 expressed in Escherichia coli BL21 codon plus cells assessed as steady state dissociation co...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Union Life Sciences

Curated by ChEMBL
LigandPNGBDBM12414(CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...)
Affinity DataKd:  1.79E+3nMpH: 7.0Assay Description:Binding affinity to human recombinant CA2 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Union Life Sciences

Curated by ChEMBL
LigandPNGBDBM12414(CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...)
Affinity DataKd:  660nMpH: 7.0 T: 2°CAssay Description:The dissociation constant of the hCA and inhibitor complex was determined by competitive displacement of a fixed concentration of dansylamide by incr...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Union Life Sciences

Curated by ChEMBL
LigandPNGBDBM12414(CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...)
Affinity DataKd:  1.15E+6nMAssay Description:Binding affinity to GST-fused human carbonic anhydrase-2 expressed in Escherichia coli BL21 codon plus cells assessed as dissociation constant by SPR...More data for this Ligand-Target Pair