TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 41nMAssay Description:Inhibition of recombinant human HDAC1 expressed in baculovirus expression system using KI-104 as substrate incubated for 3 hrs by by fluorescence-bas...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 110nMAssay Description:Inhibition of Histone deacetylase 1 induced acetylated histone in mammalian cells.More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 200nMAssay Description:Inhibition of HDAC1 in human MM96L cells assessed as activation of histone H4 acetylation at Lys5, Lys8, Lys12 and Lys16 residues by Western blot ana...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 600nMAssay Description:Inhibition of HDAC1 in human MM96L cells assessed as activation of histone H4 acetylation at Lys5, Lys8, Lys12 and Lys16 residues by Western blot ana...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 820nMAssay Description:Inhibition of Histone deacetylase 1 induced acetylated histone in mammalian cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 1.00E+3nMAssay Description:In vitro inhibition of partially purified recombinant human Histone deacetylase 1More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 1.00E+3nMAssay Description:Inhibition of human HDAC1 assessed as histone H4 acetylation in cell based assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 1.00E+3nMAssay Description:Inhibition of HDAC1 in human T24 cells assessed as induction of histone H4 acetylation after 16 hrs relative to MS-275More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 1.00E+3nMAssay Description:Concentration of compound required for acetylation of histone-4 in human T24 cancer cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 1.00E+3nMAssay Description:Inhibition of HDAC1 in human T24 cells assessed as induction of histone H4 acetylation after 16 hrs relative to MS-275More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 1.00E+3nMAssay Description:Inhibition of HDAC1 in human T24 cells assessed as induction of histone H4 acetylation after 16 hrs relative to MS-275More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 1.00E+3nMAssay Description:Inhibition of HDAC1 in human T24 cells assessed as induction of histone H4 acetylation after 16 hrs relative to MS-275More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 1.00E+3nMAssay Description:Inhibition of HDAC1 in human T24 cells assessed as induction of histone H4 acetylation after 16 hrs relative to MS-275More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 1.50E+3nMAssay Description:Concentration of compound required for acetylation of histone-4 in human T24 cancer cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 1.80E+3nMAssay Description:Inhibition of HDAC1 in human MM96L cells assessed as activation of histone H4 acetylation at Lys5, Lys8, Lys12 and Lys16 residues by Western blot ana...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 1.90E+3nMAssay Description:Inhibition of Histone deacetylase 1 induced acetylated histone in mammalian cells.More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 2.00E+3nMAssay Description:Inhibition of HDAC1 in human T24 cells assessed as induction of histone H4 acetylation after 16 hrs relative to MS-275More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 2.00E+3nMAssay Description:Inhibition of HDAC1 in human T24 cells assessed as induction of histone H4 acetylation after 16 hrs relative to MS-275More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 2.00E+3nMAssay Description:Concentration of compound required for acetylation of histone-4 in human T24 cancer cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 3.00E+3nMAssay Description:Inhibition of HDAC1 in human T24 cells assessed as induction of histone H4 acetylation after 16 hrs relative to MS-275More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 3.00E+3nMAssay Description:Inhibition of HDAC1 in human T24 cells assessed as induction of histone H4 acetylation after 16 hrs relative to MS-275More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 5.00E+3nMAssay Description:Inhibition of HDAC1 in human T24 cells assessed as induction of histone H4 acetylation after 16 hrs relative to MS-275More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 5.00E+3nMAssay Description:Concentration of compound required for acetylation of histone-4 in human T24 cancer cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 5.00E+3nMAssay Description:Concentration of compound required for acetylation of histone-4 in human T24 cancer cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 5.00E+3nMAssay Description:Concentration of compound required for acetylation of histone-4 in human T24 cancer cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 5.00E+3nMAssay Description:In vitro inhibition of partially purified recombinant human Histone deacetylase 1More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 5.00E+3nMAssay Description:In vitro inhibition of partially purified recombinant human Histone deacetylase 1More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 5.00E+3nMAssay Description:In vitro inhibition of partially purified recombinant human Histone deacetylase 1More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 5.00E+3nMAssay Description:Inhibition of human HDAC1 assessed as histone H4 acetylation in cell based assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 6.00E+3nMAssay Description:Inhibition of Histone deacetylase 1 induced acetylated histone in mammalian cells.More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 9.00E+3nMAssay Description:Inhibition of HDAC1 in human HCT116 cells assessed as inhibition of histone-H3 deacetylation after 24 hrsMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 1.00E+4nMAssay Description:Inhibition of human HDAC1 assessed as histone H4 acetylation in cell based assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 1.00E+4nMAssay Description:Concentration of compound required for acetylation of histone-4 in human T24 cancer cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 1.20E+4nMAssay Description:Concentration of compound required for acetylation of histone-4 in human T24 cancer cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 2.00E+4nMAssay Description:Concentration of compound required for acetylation of histone-4 in human T24 cancer cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 2.20E+4nMAssay Description:Concentration of compound required for acetylation of histone-4 in human T24 cancer cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: >2.50E+4nMAssay Description:Concentration of compound required for acetylation of histone-4 in human T24 cancer cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: >2.50E+4nMAssay Description:Concentration of compound required for acetylation of histone-4 in human T24 cancer cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: >2.50E+4nMAssay Description:Concentration of compound required for acetylation of histone-4 in human T24 cancer cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: >2.50E+4nMAssay Description:In vitro inhibition of partially purified recombinant human Histone deacetylase 1More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: >2.50E+4nMAssay Description:Concentration of compound required for acetylation of histone-4 in human T24 cancer cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: >2.50E+4nMAssay Description:In vitro inhibition of partially purified recombinant human Histone deacetylase 1More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: >2.50E+4nMAssay Description:Concentration of compound required for acetylation of histone-4 in human T24 cancer cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 2.50E+4nMAssay Description:Inhibition of human HDAC1 assessed as histone H4 acetylation in cell based assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: >2.50E+4nMAssay Description:Concentration of compound required for acetylation of histone-4 in human T24 cancer cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: >2.50E+4nMAssay Description:Concentration of compound required for acetylation of histone-4 in human T24 cancer cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 3.60E+4nMAssay Description:Inhibition of Histone deacetylase 1 induced acetylated histone in mammalian cells.More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of HDAC1 in human HCT116 cells assessed as inhibition of histone-H3 deacetylation after 24 hrsMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S£O Paulo State University (Unesp)
Curated by ChEMBL
S£O Paulo State University (Unesp)
Curated by ChEMBL
Affinity DataEC50: 2.17E+5nMAssay Description:Inhibition of Histone deacetylase 1 induced acetylated histone in mammalian cells.More data for this Ligand-Target Pair