Compile Data Set for Download or QSAR
maximum 50k data
Found 714 of ec50 data for polymerid = 2411,50002741,50003355
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384640(CHEMBL2036954)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human recombinant GPR109a expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384612(CHEMBL2036958)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human recombinant GPR109a expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384641(CHEMBL2036955)
Affinity DataEC50:  2nMAssay Description:Agonist activity at rat GPR109aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384637(CHEMBL2036951)
Affinity DataEC50:  2nMAssay Description:Agonist activity at rat GPR109aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384637(CHEMBL2036951)
Affinity DataEC50:  3nMAssay Description:Agonist activity at human recombinant GPR109a expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50337038(5-(3-cyclopropylpropyl)-2-(difluoromethyl)-3H-pyra...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at rat GPR109aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50337038(5-(3-cyclopropylpropyl)-2-(difluoromethyl)-3H-pyra...)
Affinity DataEC50:  4nMAssay Description:Agonist activity at mouse GPR109aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384634(CHEMBL2036948)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human recombinant GPR109a expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384640(CHEMBL2036954)
Affinity DataEC50:  4nMAssay Description:Agonist activity at mouse GPR109aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384634(CHEMBL2036948)
Affinity DataEC50:  4nMAssay Description:Agonist activity at rat GPR109aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384641(CHEMBL2036955)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human recombinant GPR109a expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384636(CHEMBL2036950)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human recombinant GPR109a expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384637(CHEMBL2036951)
Affinity DataEC50:  5nMAssay Description:Agonist activity at mouse GPR109aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384640(CHEMBL2036954)
Affinity DataEC50:  5nMAssay Description:Agonist activity at rat GPR109aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50337024(2-(difluoromethyl)-5-(3-(1-methylcyclopropyl)propy...)
Affinity DataEC50:  6nMAssay Description:Agonist activity at rat GPR109aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM23525(2-{3-[2-(2-chloro-4-hydroxyphenyl)-1,3-thiazol-5-y...)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human recombinant GPR109A receptor expressed in CHO-K1 cells after 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50319112((4S,5R)-2-(3-(3-(5-hydroxypyridin-2-yl)-1,2,4-oxad...)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human niacin receptor expressed in CHO-KI cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM23525(2-{3-[2-(2-chloro-4-hydroxyphenyl)-1,3-thiazol-5-y...)
Affinity DataIC50:  1nM EC50:  6nMpH: 7.4 T: 2°CAssay Description:Membranes were incubated in binding buffer with [5, 6-3H]-niacin in the presence of test compound. After 4 hours at room temperature, reactions were ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384612(CHEMBL2036958)
Affinity DataEC50:  6nMAssay Description:Agonist activity at mouse GPR109aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50277715(2-(3-(7-hydroxynaphtho[2,1-d]isoxazol-3-yl)propana...)
Affinity DataEC50:  6.5nMAssay Description:Agonist activity at human GPR109A expressed in CHOK1 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384644(CHEMBL2036960)
Affinity DataEC50:  7nMAssay Description:Agonist activity at human recombinant GPR109a expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384616(CHEMBL2036813)
Affinity DataEC50:  8nMAssay Description:Agonist activity at rat GPR109aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384612(CHEMBL2036958)
Affinity DataEC50:  8nMAssay Description:Agonist activity at rat GPR109aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM23515(CHEMBL573 | Niacin | Nicotinic Acid | [5, 6-3H]-ni...)
Affinity DataEC50:  8.70nMAssay Description:Agonist activity at human GPR109a expressed in human adipocytes assessed as decrease in intracellular cAMP level by HTRF assayChecked by AuthorMore data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM23515(CHEMBL573 | Niacin | Nicotinic Acid | [5, 6-3H]-ni...)
Affinity DataEC50:  8.70nMAssay Description:Agonist activity at human GPR109a expressed in human adipocytes assessed as decrease in intracellular cAMP level by HTRF assayChecked by AuthorMore data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50268973(CHEMBL4082765)
Affinity DataEC50:  9nMAssay Description:Agonist activity at recombinant human HCA2 receptor expressed in Flp-IN HEK cells assessed as reduction in forskolin-stimulated cAMP accumulation mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384638(CHEMBL2036952)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human recombinant GPR109a expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50319095(2-(3-(6-hydroxynaphthalen-2-yl)propanamido)-5-prop...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human niacin receptor expressed in CHO-KI cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384643(CHEMBL2036957)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human recombinant GPR109a expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50405697(CHEMBL4164140)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human GPR109a expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50319102(5-(3,5-difluorophenyl)-2-(3-(6-hydroxynaphthalen-2...)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human niacin receptor expressed in CHO-KI cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384630(CHEMBL2036828)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human recombinant GPR109a expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50405697(CHEMBL4164140)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human GPR109a expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384616(CHEMBL2036813)
Affinity DataEC50:  12nMAssay Description:Agonist activity at mouse GPR109aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388230(CHEMBL2057618)
Affinity DataEC50:  12.9nMAssay Description:Agonist activity at human GPR109a expressed in CHO cells assessed as decrease in forskolin-stimulated cAMP production by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384639(CHEMBL2036953)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human recombinant GPR109a expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388228(CHEMBL2057610)
Affinity DataEC50:  14nMAssay Description:Agonist activity at human GPR109a expressed in CHO cells assessed as decrease in forskolin-stimulated cAMP production by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM23515(CHEMBL573 | Niacin | Nicotinic Acid | [5, 6-3H]-ni...)
Affinity DataEC50:  14.5nMAssay Description:Agonist activity at GPR109A (unknown origin) assessed as effect on beta-arrestin2 conformational changesMore data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50337024(2-(difluoromethyl)-5-(3-(1-methylcyclopropyl)propy...)
Affinity DataEC50:  15nMAssay Description:Agonist activity at mouse GPR109aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50541467(CHEMBL4647392)
Affinity DataEC50:  15nMAssay Description:Agonist activity at GPR109A receptor (unknown origin) expressed in HEK293T cell membranes after 30 mins by [35S]GTPgammaS binding based microbeta sci...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384645(CHEMBL2035002)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human recombinant GPR109a expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50313976(2-({3-[3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5...)
Affinity DataEC50:  16nMAssay Description:Agonist activity at cloned human GPR109A receptor expressed in CHO-K1 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384647(CHEMBL2036959)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human recombinant GPR109a expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384616(CHEMBL2036813)
Affinity DataEC50:  17nMAssay Description:Agonist activity at human recombinant GPR109a expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50319109(2-(3-(3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-...)
Affinity DataEC50:  17nMAssay Description:Agonist activity at human niacin receptor expressed in CHO-KI cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM23515(CHEMBL573 | Niacin | Nicotinic Acid | [5, 6-3H]-ni...)
Affinity DataEC50:  17.6nMAssay Description:Agonist activity at GPR109A (unknown origin) assessed as inhibition of forskolin-mediated cAMP accumulation after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50277714(2-(3-(7-hydroxy-4,5-dihydronaphtho[2,1-d]isoxazol-...)
Affinity DataEC50:  19nMAssay Description:Agonist activity at human GPR109A expressed in CHOK1 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384627(CHEMBL2036825)
Affinity DataEC50:  19nMAssay Description:Agonist activity at human recombinant GPR109a expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM23515(CHEMBL573 | Niacin | Nicotinic Acid | [5, 6-3H]-ni...)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human GPR109a expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated c...More data for this Ligand-Target Pair
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50313977(2-(3-(3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5-...)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human niacin receptor expressed in CHO-KI cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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