Compile Data Set for Download or QSAR
maximum 50k data
Found 18 of ec50 data for polymerid = 452
TargetTelomerase protein component 1(Homo sapiens (Human))
Geron

US Patent
LigandPNGBDBM279791(PMPG free acid, R form | US10035814, Compound 1426...)
Affinity DataEC50:  850nMpH: 8.5Assay Description:(((Guanine-9-yl) propan-2-oxy) methyl) phosphonic acid diphosphate (PMPGpp) acts as a chain terminator and competes with dGTP.Purified human telomera...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetTelomerase protein component 1(Homo sapiens (Human))
Geron

US Patent
LigandPNGBDBM279797(PMIBeG, free acid | US10035814, Compound 142810)
Affinity DataEC50:  1.40E+3nMpH: 8.5Assay Description:(((Guanine-9-yl) propan-2-oxy) methyl) phosphonic acid diphosphate (PMPGpp) acts as a chain terminator and competes with dGTP.Purified human telomera...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetTelomerase protein component 1(Homo sapiens (Human))
Geron

US Patent
LigandPNGBDBM279807(PMPG-C10 amidate | US10035814, Compound 142962)
Affinity DataEC50:  1.44E+3nMAssay Description:Telomerase inhibition is observed in cells following the addition of the prodrugs (R)-PMPG-diisopropyloxy ester or (S)-PMPG-diisopropyloxy ester. HT3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTelomerase protein component 1(Homo sapiens (Human))
Geron

US Patent
LigandPNGBDBM279793(PMPG(lin) | US10035814, Compound 142848)
Affinity DataEC50:  1.50E+3nMpH: 8.5Assay Description:(((Guanine-9-yl) propan-2-oxy) methyl) phosphonic acid diphosphate (PMPGpp) acts as a chain terminator and competes with dGTP.Purified human telomera...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetTelomerase protein component 1(Homo sapiens (Human))
Geron

US Patent
LigandPNGBDBM279808(US10035814, Compound 142942 | bis-PMPG spermine)
Affinity DataEC50:  1.84E+3nMAssay Description:Telomerase inhibition is observed in cells following the addition of the prodrugs (R)-PMPG-diisopropyloxy ester or (S)-PMPG-diisopropyloxy ester. HT3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTelomerase protein component 1(Homo sapiens (Human))
Geron

US Patent
LigandPNGBDBM279801(PMPG prodrug, R form | US10035814, Compound 142715)
Affinity DataEC50:  2.15E+3nMAssay Description:Telomerase inhibition is observed in cells following the addition of the prodrugs (R)-PMPG-diisopropyloxy ester or (S)-PMPG-diisopropyloxy ester. HT3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTelomerase protein component 1(Homo sapiens (Human))
Geron

US Patent
LigandPNGBDBM279803(PMIBeG free acid | US10035814, Compound 142811)
Affinity DataEC50:  2.60E+3nMAssay Description:Telomerase inhibition is observed in cells following the addition of the prodrugs (R)-PMPG-diisopropyloxy ester or (S)-PMPG-diisopropyloxy ester. HT3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTelomerase protein component 1(Homo sapiens (Human))
Geron

US Patent
LigandPNGBDBM279799(PMP(2)G | US10035814, Compound 142879)
Affinity DataEC50:  3.10E+3nMpH: 8.5Assay Description:(((Guanine-9-yl) propan-2-oxy) methyl) phosphonic acid diphosphate (PMPGpp) acts as a chain terminator and competes with dGTP.Purified human telomera...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetTelomerase protein component 1(Homo sapiens (Human))
Geron

US Patent
LigandPNGBDBM279798(PMIBaG (mix R,S) | US10035814, Compound 142846)
Affinity DataEC50:  4.40E+3nMpH: 8.5Assay Description:(((Guanine-9-yl) propan-2-oxy) methyl) phosphonic acid diphosphate (PMPGpp) acts as a chain terminator and competes with dGTP.Purified human telomera...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetTelomerase protein component 1(Homo sapiens (Human))
Geron

US Patent
LigandPNGBDBM279806(PMPG spermidine, R form | US10035814, Compound 142...)
Affinity DataEC50:  5.00E+3nMAssay Description:Telomerase inhibition is observed in cells following the addition of the prodrugs (R)-PMPG-diisopropyloxy ester or (S)-PMPG-diisopropyloxy ester. HT3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTelomerase protein component 1(Homo sapiens (Human))
Geron

US Patent
LigandPNGBDBM279805(PMIBeG spermidine | US10035814, Compound 142873)
Affinity DataEC50:  6.70E+3nMAssay Description:Telomerase inhibition is observed in cells following the addition of the prodrugs (R)-PMPG-diisopropyloxy ester or (S)-PMPG-diisopropyloxy ester. HT3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTelomerase protein component 1(Homo sapiens (Human))
Geron

US Patent
LigandPNGBDBM279796(FPMPG | US10035814, Compound 142856)
Affinity DataEC50:  7.50E+3nMpH: 8.5Assay Description:(((Guanine-9-yl) propan-2-oxy) methyl) phosphonic acid diphosphate (PMPGpp) acts as a chain terminator and competes with dGTP.Purified human telomera...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetTelomerase protein component 1(Homo sapiens (Human))
Geron

US Patent
LigandPNGBDBM279802(6-thio-G- phosphonate (6-S- PMPG), R form | US1003...)
Affinity DataEC50:  7.54E+3nMAssay Description:Telomerase inhibition is observed in cells following the addition of the prodrugs (R)-PMPG-diisopropyloxy ester or (S)-PMPG-diisopropyloxy ester. HT3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTelomerase protein component 1(Homo sapiens (Human))
Geron

US Patent
LigandPNGBDBM279794(PM(3)BG | US10035814, Compound 142916)
Affinity DataEC50:  1.00E+4nMpH: 8.5Assay Description:(((Guanine-9-yl) propan-2-oxy) methyl) phosphonic acid diphosphate (PMPGpp) acts as a chain terminator and competes with dGTP.Purified human telomera...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetTelomerase protein component 1(Homo sapiens (Human))
Geron

US Patent
LigandPNGBDBM279804(PMPeG, prodrug | US10035814, Compound 142820)
Affinity DataEC50:  1.09E+4nMAssay Description:Telomerase inhibition is observed in cells following the addition of the prodrugs (R)-PMPG-diisopropyloxy ester or (S)-PMPG-diisopropyloxy ester. HT3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTelomerase protein component 1(Homo sapiens (Human))
Geron

US Patent
LigandPNGBDBM279800(PMPG free acid, R form | US10035814, Compound 1426...)
Affinity DataEC50:  1.17E+4nMAssay Description:Telomerase inhibition is observed in cells following the addition of the prodrugs (R)-PMPG-diisopropyloxy ester or (S)-PMPG-diisopropyloxy ester. HT3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTelomerase protein component 1(Homo sapiens (Human))
Geron

US Patent
LigandPNGBDBM279792(6-thio-G- phosphonate (6-S-PMPG), R form | US10035...)
Affinity DataEC50:  1.35E+4nMpH: 8.5Assay Description:(((Guanine-9-yl) propan-2-oxy) methyl) phosphonic acid diphosphate (PMPGpp) acts as a chain terminator and competes with dGTP.Purified human telomera...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetTelomerase protein component 1(Homo sapiens (Human))
Geron

US Patent
LigandPNGBDBM279795(PM(2)BG | US10035814, Compound 142915)
Affinity DataEC50: >6.00E+4nMpH: 8.5Assay Description:(((Guanine-9-yl) propan-2-oxy) methyl) phosphonic acid diphosphate (PMPGpp) acts as a chain terminator and competes with dGTP.Purified human telomera...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent