Compile Data Set for Download or QSAR
maximum 50k data
Found 125 of ec50 data for polymerid = 49000138
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50421887(CHEMBL2112181)
Affinity DataEC50:  5.40nMAssay Description:Prolongation of the stimulus-QRS interval by 50% of the maximum response at the Adenosine A1 receptor in langendorff guinea pig heart preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)
Affinity DataEC50:  7.90nMAssay Description:Agonist activity at adenosine A1 receptor in pig cortical membrane assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM25400((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)
Affinity DataEC50:  12.6nMAssay Description:Prolongation of the stimulus-QRS interval by 50% of the maximum response at the adenosine A1 receptor in langendorff guinea pig heart preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50224759((2R,3R,4S,5R)-2-(2-chloro-6-((R)-tetrahydrofuran-3...)
Affinity DataEC50:  18.3nMAssay Description:Agonist activity at adenosine A1 receptor in pig cortical membrane assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50138530((2R,3R,5R)-2-Hydroxymethyl-5-{6-[(R)-(tetrahydro-f...)
Affinity DataEC50:  31.6nMAssay Description:Agonist activity at adenosine A1 receptor in pig cortical membrane assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50367678(CHEMBL605469)
Affinity DataEC50:  33.9nMAssay Description:Prolongation of the stimulus-QRS interval by 50% of the maximum response at the Adenosine A1 receptor in langendorff guinea pig heart preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50138530((2R,3R,5R)-2-Hydroxymethyl-5-{6-[(R)-(tetrahydro-f...)
Affinity DataEC50:  41nMAssay Description:Binding affinity against adenosine A1 receptor using [3H]CPX in guinea pig DDT membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataEC50:  63.1nMAssay Description:Prolongation of the stimulus-QRS interval by 50% of the maximum response at the Adenosine A1 receptor in langendorff guinea pig heart preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50224760(2-chloro-N6-cyclopentyl-9H-(2-C-methyl-5-Nmethylca...)
Affinity DataEC50:  165nMAssay Description:Agonist activity at adenosine A1 receptor in pig cortical membrane assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50009525(2-CI Adenosine | 2-Chloroadenosine | 2-Chloroado |...)
Affinity DataEC50:  191nMAssay Description:Prolongation of the stimulus-QRS interval by 50% of the maximum response at the adenosine A1 receptor in langendorff guinea pig heart preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50366924(CHEMBL609539)
Affinity DataEC50:  200nMAssay Description:Binding affinity against adenosine A1 receptor using [3H]CPX in guinea pig DDT membrane; 3612+/-1937More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50224769(2-chloro-N6-cyclopentyl-9H-(2-C-methyl-5-N-methylt...)
Affinity DataEC50:  326nMAssay Description:Agonist activity at adenosine A1 receptor in pig cortical membrane assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50368463(CHEMBL608175)
Affinity DataEC50:  832nMAssay Description:Tested for adenosine A1 receptor agonistic activity by determining concentration needed to prolong the stimulus-QRS interval by 50% of the maximum re...Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM82031(2-Oxoado (isoguanosine) | CAS_1818-71-9 | isoguano...)
Affinity DataEC50:  1.15E+3nMAssay Description:Prolongation of the stimulus-QRS interval by 50% of the maximum response at the Adenosine A1 receptor in langendorff guinea pig heart preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50267574(CHEMBL489638 | N6-Tetrahydrofuranyl-9H-[5-deoxy-5-...)
Affinity DataEC50:  1.26E+3nMAssay Description:Binding affinity against adenosine A1 receptor using [3H]CPX in guinea pig DDT membrane; 543+/-182More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50368251(CHEMBL605879)
Affinity DataEC50:  2.19E+3nMAssay Description:Prolongation of the stimulus-QRS interval by 50% of the maximum response at the Adenosine A1 receptor in langendorff guinea pig heart preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50224762(CHEMBL254483 | N6-(R)-3-tetrahydrofuranyl-9H-(2-C-...)
Affinity DataEC50:  2.40E+3nMAssay Description:Agonist activity at adenosine A1 receptor in pig cortical membrane assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50368472(CHEMBL611920)
Affinity DataEC50:  2.63E+3nMAssay Description:Tested for adenosine A1 receptor agonistic activity by determining concentration needed to prolong the stimulus-QRS interval by 50% of the maximum re...Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50368264(CHEMBL603588)
Affinity DataEC50:  2.63E+3nMAssay Description:Prolongation of the stimulus-QRS interval by 50% of the maximum response at the Adenosine A1 receptor in langendorff guinea pig heart preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50224764(2-chloro-2'-C-methyl-tecadenoson | CHEMBL400782)
Affinity DataEC50:  2.76E+3nMAssay Description:Agonist activity at adenosine A1 receptor in pig cortical membrane assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50138533(CHEMBL150950 | Methyl-carbamic acid (2R,3R,5R)-3,4...)
Affinity DataEC50:  2.80E+3nMAssay Description:Agonistic activity against adenosine A1 receptor in guinea pig isolated heartsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50368485(CHEMBL611609)
Affinity DataEC50:  3.02E+3nMAssay Description:Tested for adenosine A1 receptor agonistic activity by determining concentration needed to prolong the stimulus-QRS interval by 50% of the maximum re...Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM14487((2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxy...)
Affinity DataEC50:  3.39E+3nMAssay Description:Effective concentration required for prolongation of the stimulus-QRS interval by 50% of the maximum response at the A1 adenosine receptor in langend...More data for this Ligand-Target Pair
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM14487((2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxy...)
Affinity DataEC50:  3.39E+3nMAssay Description:Prolongation of the stimulus-QRS interval by 50% of the maximum response at the adenosine A1 receptor in langendorff guinea pig heart preparationChecked by AuthorMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50230152(Binodenoson | Corvue | MRE0470 | WRC-0470)
Affinity DataEC50:  3.55E+3nMAssay Description:In vitro prolonging of the stimulus-QRS interval in guinea pig heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50224778(2'-Me-tecadenoson | CHEMBL400190)
Affinity DataEC50:  3.62E+3nMAssay Description:Agonist activity at adenosine A1 receptor in pig cortical membrane assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50421974(CHEMBL607873)
Affinity DataEC50:  3.63E+3nMAssay Description:In vitro prolonging of the stimulus-QRS interval in guinea pig heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50368250(CHEMBL605254)
Affinity DataEC50:  3.72E+3nMAssay Description:Prolongation of the stimulus-QRS interval by 50% of the maximum response at the adenosine A1 receptor in langendorff guinea pig heart preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50368471(CHEMBL608174)
Affinity DataEC50:  4.17E+3nMAssay Description:Tested for adenosine A1 receptor agonistic activity by determining concentration needed to prolong the stimulus-QRS interval by 50% of the maximum re...Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50368253(CHEMBL603373)
Affinity DataEC50:  4.47E+3nMAssay Description:Prolongation of the stimulus-QRS interval by 50% of the maximum response at the Adenosine A1 receptor in langendorff guinea pig heart preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50406502(CHEMBL604212)
Affinity DataEC50:  4.57E+3nMAssay Description:Effective concentration required for prolongation of the stimulus-QRS interval by 50% of the maximum response at the A1 adenosine receptor in langend...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50224768(2-chloro-N6-cyclopentyl-9H-(2-C-methyl-5-N-benzylc...)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at adenosine A1 receptor in pig cortical membrane assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50364062(CHEMBL1950555)
Affinity DataEC50:  5.62E+3nMAssay Description:Prolongation of the stimulus-QRS interval by 50% of the maximum response at the adenosine A1 receptor in langendorff guinea pig heart preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50406517(CHEMBL606082)
Affinity DataEC50:  6.31E+3nMAssay Description:Effective concentration required for prolongation of the stimulus-QRS interval by 50% of the maximum response at the Adenosine A1 receptor in langend...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50406505(CHEMBL605257)
Affinity DataEC50:  7.08E+3nMAssay Description:Effective concentration required for prolongation of the stimulus-QRS interval by 50% of the maximum response at the A1 adenosine receptor in langend...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50421975(CHEMBL611607)
Affinity DataEC50:  7.24E+3nMAssay Description:In vitro prolonging of the stimulus-QRS interval in guinea pig heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50368543(CHEMBL605668)
Affinity DataEC50:  7.41E+3nMAssay Description:Effective concentration required for prolongation of the stimulus-QRS interval by 50% of the maximum response at the Adenosine A1 receptor in langend...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50406507(CHEMBL604837)
Affinity DataEC50:  8.32E+3nMAssay Description:Effective concentration required for prolongation of the stimulus-QRS interval by 50% of the maximum response at the A1 adenosine receptor in langend...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50368261(CHEMBL605247)
Affinity DataEC50:  8.71E+3nMAssay Description:Prolongation of the stimulus-QRS interval by 50% of the maximum response at the adenosine A1 receptor in langendorff guinea pig heart preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50368258(CHEMBL606093)
Affinity DataEC50:  8.71E+3nMAssay Description:Prolongation of the stimulus-QRS interval by 50% of the maximum response at the adenosine A1 receptor in langendorff guinea pig heart preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50421987(CHEMBL611919)
Affinity DataEC50:  8.91E+3nMAssay Description:In vitro prolonging of the stimulus-QRS interval in guinea pig heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50368480(CHEMBL607590)
Affinity DataEC50:  8.91E+3nMAssay Description:Tested for adenosine A1 receptor agonistic activity by determining concentration needed to prolong the stimulus-QRS interval by 50% of the maximum re...Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50368487(CHEMBL607508)
Affinity DataEC50:  9.12E+3nMAssay Description:Tested for adenosine A1 receptor agonistic activity by determining concentration needed to prolong the stimulus-QRS interval by 50% of the maximum re...Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50421888(CHEMBL2311198)
Affinity DataEC50:  9.33E+3nMAssay Description:Prolongation of the stimulus-QRS interval by 50% of the maximum response at the adenosine A1 receptor in langendorff guinea pig heart preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50421982(CHEMBL608663)
Affinity DataEC50:  9.77E+3nMAssay Description:In vitro prolonging of the stimulus-QRS interval in guinea pig heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50421978(CHEMBL611314)
Affinity DataEC50:  1.10E+4nMAssay Description:In vitro prolonging of the stimulus-QRS interval in guinea pig heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50406504(CHEMBL605878)
Affinity DataEC50:  1.15E+4nMAssay Description:Effective concentration required for prolongation of the stimulus-QRS interval by 50% of the maximum response at the Adenosine A1 receptor in langend...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50421979(CHEMBL607585)
Affinity DataEC50:  1.15E+4nMAssay Description:In vitro prolonging of the stimulus-QRS interval in guinea pig heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50406509(CHEMBL605667)
Affinity DataEC50:  1.17E+4nMAssay Description:Effective concentration required for prolongation of the stimulus-QRS interval by 50% of the maximum response at the Adenosine A1 receptor in langend...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50368467(CHEMBL607886)
Affinity DataEC50:  1.20E+4nMAssay Description:Tested for adenosine A1 receptor agonistic activity by determining concentration needed to prolong the stimulus-QRS interval by 50% of the maximum re...Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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