Affinity DataEC50: 98nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 106nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 114nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 180nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 201nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 302nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 372nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 377nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 400nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 487nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.18E+3nMAssay Description:Agonist activity at human mGlu7 receptor expressed in HEK293 assessed as inhibition of forskolin stimulated cAMP productionMore data for this Ligand-Target Pair
Affinity DataEC50: 1.34E+3nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5.20E+3nMAssay Description:Agonist activity at human mGlu 7 expressed in HEK293 cells by Ca+2 assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu7 receptor expressed in HEK293 cells by fluorescent Ca2+ assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu7 receptor expressed in HEK293 cells by fluorescent Ca2+ assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation at mGluR7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGlu7 receptor assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGlu7 receptor assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation at mGluR7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu7 receptor expressed in HEK293 cells by fluorescent Ca2+ assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:In vitro binding affinity for PPAR-gammaMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGluR7More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu7 receptor expressed in HEK293 cells assessed as calcium mobilization by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu7 receptor expressed in HEK293 cells assessed as calcium mobilization by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGlu7 receptor assessed as potentiation of glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu7 receptor expressed in HEK293 cells by fluorescent Ca2+ assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.16E+4nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at recombinant human mGlu7 receptor expressed in hamster AV12 cells co-expressing human EAAT1/Galpha1s assessed as increase in Ca2+ ...More data for this Ligand-Target Pair
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at human recombinant mGlu7 receptor expressed in AV12 cells assessed as stimulation of Ca2+ mobilization after 1 hr by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at recombinant human mGlu7 receptor expressed in hamster AV12 cells co-expressing rat EAAT1/Galpha15 assessed as induction of increa...More data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation activity at mGlu7 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 3.90E+4nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
Affinity DataEC50: 4.80E+4nMAssay Description:Compound was evaluated for the inhibition of forskolin stimulated cAMP accumulation in CHO cells expressing hmGluR4aMore data for this Ligand-Target Pair
Affinity DataEC50: 4.80E+4nMAssay Description:Compound was evaluated for the inhibition of forskolin stimulated cAMP accumulation in CHO cells expressing hmGluR7bMore data for this Ligand-Target Pair
Affinity DataEC50: 5.12E+4nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
Affinity DataEC50: 5.30E+4nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
Affinity DataEC50: 5.38E+4nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
Affinity DataEC50: 6.20E+4nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
Affinity DataEC50: 6.30E+4nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
Affinity DataEC50: 6.90E+4nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
Affinity DataEC50: 8.90E+4nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of forskolin stimulated cAMP production in RGT cells expressing recombinant human mGluR7More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of forskolin stimulated cAMP production in RGT cells expressing recombinant human mGluR7More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of forskolin stimulated cAMP production in RGT cells expressing recombinant human mGluR7More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mGlu7 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair