Compile Data Set for Download or QSAR
maximum 50k data
Found 33 of ec50 data for polymerid = 49000985,49000986,50006202
TargetP2X purinoceptor 4(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118219(Bz-ATP | CHEMBL339386)
Affinity DataEC50:  490nMAssay Description:Antagonist activity against recombinant human P2X purinoceptor 4 (P2X4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50366480(ADENOSINE TRIPHOSPHATE | ATP)
Affinity DataEC50:  500nMAssay Description:Antagonist activity against recombinant human P2X purinoceptor 4 (P2X4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50366480(ADENOSINE TRIPHOSPHATE | ATP)
Affinity DataEC50:  1.00E+3nMAssay Description:Antagonist activity at human P2X4 receptor expressed in 1321N1 cells assessed as inhibition of ATP-induced cytosolic calcium influx compound preincub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(RAT)
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50366480(ADENOSINE TRIPHOSPHATE | ATP)
Affinity DataEC50:  1.00E+3nMAssay Description:Antagonist activity at rat P2X4 receptor by cell-based calcium influx assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(RAT)
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50366480(ADENOSINE TRIPHOSPHATE | ATP)
Affinity DataEC50:  1.00E+3nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 4 (P2X4) 3 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Mus musculus)
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50366480(ADENOSINE TRIPHOSPHATE | ATP)
Affinity DataEC50:  1.00E+3nMAssay Description:Antagonist activity at mouse P2X4 receptor by cell-based calcium influx assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118232(2-MeSATP | ATP, 2-meS | CHEMBL336208)
Affinity DataEC50:  1.00E+3nMAssay Description:Antagonist activity against recombinant human P2X purinoceptor 4 (P2X4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118220((ppA)2 | A(5')p4(5')A | CHEMBL339385 | P(1),P(4)-b...)
Affinity DataEC50:  1.00E+3nMAssay Description:Antagonist activity against recombinant human P2X purinoceptor 4 (P2X4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50594505(CHEMBL5177316)
Affinity DataEC50:  1.48E+3nMAssay Description:Agonist activity at human P2X4R expressing HEK293 cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 4(RAT)
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50118217(ADENOSINE-5'-DIPHOSPHATE MONOTHIOPHOSPHATE | ATP-g...)
Affinity DataEC50:  2.30E+3nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 4 (P2X4) 3 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(RAT)
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50118232(2-MeSATP | ATP, 2-meS | CHEMBL336208)
Affinity DataEC50:  7.40E+3nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 4 (P2X4) 3 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50596624(CHEMBL5204261)
Affinity DataEC50:  8.97E+3nMAssay Description:Negative allosteric modulation activity at human P2X4 receptor expressed in human 1321N1 cells assessed as ATP induced calcium response by measuring ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 4(RAT)
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50118229(CHEMBL129841 | MRS 2179)
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity against recombinant rat P2X purinoceptor 4 (P2X4) at 3 uM,expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(RAT)
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity against recombinant rat P2X purinoceptor 4 (P2X4) at 3 uM,expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)
Affinity DataEC50:  1.00E+4nMAssay Description:Antagonist activity against recombinant human P2X purinoceptor 4 (P2X4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Mus musculus)
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50118232(2-MeSATP | ATP, 2-meS | CHEMBL336208)
Affinity DataEC50:  1.00E+4nMAssay Description:Antagonist activity at mouse P2X4 receptor by cell-based calcium influx assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118232(2-MeSATP | ATP, 2-meS | CHEMBL336208)
Affinity DataEC50:  1.00E+4nMAssay Description:Antagonist activity at human P2X4 receptor expressed in 1321N1 cells assessed as inhibition of ATP-induced cytosolic calcium influx compound preincub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(RAT)
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50118232(2-MeSATP | ATP, 2-meS | CHEMBL336208)
Affinity DataEC50:  1.00E+4nMAssay Description:Antagonist activity at rat P2X4 receptor by cell-based calcium influx assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50598322(CHEMBL5200114)
Affinity DataEC50:  1.01E+4nMAssay Description:Antagonist activity against human P2X4R stably transfected in human 1321N1 cells assessed as ATP EC50 at 0.1 uM incubated for 30 mins by Fura-2 AM st...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50596624(CHEMBL5204261)
Affinity DataEC50:  1.01E+4nMAssay Description:Negative allosteric modulation activity at human P2X4 receptor expressed in human 1321N1 cells assessed as ATP induced calcium response by measuring ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50598322(CHEMBL5200114)
Affinity DataEC50:  1.08E+4nMAssay Description:Antagonist activity against human P2X4R stably transfected in human 1321N1 cells assessed as ATP EC50 at 0.2 uM incubated for 30 mins by Fura-2 AM st...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50598322(CHEMBL5200114)
Affinity DataEC50:  1.08E+4nMAssay Description:Antagonist activity against human P2X4R stably transfected in human 1321N1 cells assessed as ATP EC50 at 0.05 uM incubated for 30 mins by Fura-2 AM s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50596624(CHEMBL5204261)
Affinity DataEC50:  1.22E+4nMAssay Description:Negative allosteric modulation activity at human P2X4 receptor expressed in human 1321N1 cells assessed as ATP induced calcium response by measuring ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 4(RAT)
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50118226(CHEMBL337062 | PAPET-ATP)
Affinity DataEC50:  1.50E+4nMAssay Description:Antagonist activity against recombinant rat P2X purinoceptor 4 (P2X4) at 3 uM,expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(RAT)
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50118240(((2R,3S,4R,5R)-5-(6-amino-2-(hexylthio)-9H-purin-9...)
Affinity DataEC50:  2.00E+4nMAssay Description:Antagonist activity against recombinant rat P2X purinoceptor 4 (P2X4) at 3 uM,expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118230(5'-O-[(R)-HYDROXY(THIOPHOSPHONOOXY)PHOSPHORYL]ADEN...)
Affinity DataEC50:  2.50E+4nMAssay Description:Antagonist activity against recombinant human P2X purinoceptor 4 (P2X4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(RAT)
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50368125(ADENOSINE DIPHOSPHATE | ADP)
Affinity DataEC50:  2.80E+4nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 4 (P2X4) 3 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(RAT)
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50118221(9H-purine derivative | CHEMBL132722 | DIPHOSPHOMET...)
Affinity DataEC50:  3.30E+4nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 4 (P2X4) 3 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(RAT)
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50336799(5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino...)
Affinity DataEC50: >1.00E+5nMAssay Description:Antagonist activity against recombinant rat P2X purinoceptor 4 (P2X4) at 3 uM,expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50087267((1-(N,O-bis(1,5-isoquinolinesulfonyl)-N-methyl-L-t...)
Affinity DataEC50:  1.00E+5nMAssay Description:Antagonist activity against recombinant human P2X purinoceptor 4 (P2X4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50594506(CHEMBL5183218)
Affinity DataEC50: <1.00E+5nMAssay Description:Agonist activity at human P2X4R expressing HEK293 cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 4(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50029031(1-Amino-4-{4-[4-chloro-6-(3-sulfo-phenylamino)-[1,...)
Affinity DataEC50:  1.28E+5nMAssay Description:Antagonist activity against recombinant human P2X purinoceptor 4 (P2X4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(RAT)
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50118216((4-formyl-5-hydroxy-6-methylpyridin-3-yl)methyl di...)
Affinity DataEC50:  2.19E+5nMAssay Description:The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 4 (P2X4) at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed