Compile Data Set for Download or QSAR
maximum 50k data
Found 134 of ec50 data for polymerid = 50003370,50004817
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50028262(CHEMBL3354640)
Affinity DataEC50:  0.0800nMAssay Description:Agonist activity at human TLR4 expressed in HEK293 cells coexpressed with human MD2/CD14 assessed as activation of NFkappaB signaling after 20 to 24 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50028261(CHEMBL3354639)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at human TLR4 expressed in HEK293 cells coexpressed with human MD2/CD14 assessed as activation of NFkappaB signaling after 20 to 24 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM633254(Preparation of N—[(R)-3-Decyloxytetradecanoyl]-O-[...)
Affinity DataEC50:  0.780nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM633254(Preparation of N—[(R)-3-Decyloxytetradecanoyl]-O-[...)
Affinity DataEC50:  1.32nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM633254(Preparation of N—[(R)-3-Decyloxytetradecanoyl]-O-[...)
Affinity DataEC50:  1.39nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM633256(Preparation of N—[(R)-3-Decyloxytetradecanoyl]-O-[...)
Affinity DataEC50:  2.90nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM633253(Preparation of N—[(R)-3-Decanoyloxytetradecanoyl]-...)
Affinity DataEC50:  3.95nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM633259(Preparation of 2-[(R)-3-(8-phenyl)octanoyloxytetra...)
Affinity DataEC50:  4.99nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM633251(Preparation of 2-[(R)-3-decanoyloxytetradecanoylam...)
Affinity DataEC50:  10.2nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM633251(Preparation of 2-[(R)-3-decanoyloxytetradecanoylam...)
Affinity DataEC50:  13.7nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM633260(Preparation of 2-[(R)-3-decanoyloxytetradecanoylam...)
Affinity DataEC50:  15.7nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM633251(Preparation of 2-[(R)-3-decanoyloxytetradecanoylam...)
Affinity DataEC50:  19.7nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50028263(CHEMBL3354641)
Affinity DataEC50:  31nMAssay Description:Agonist activity at human TLR4 expressed in HEK293 cells coexpressed with human MD2/CD14 assessed as activation of NFkappaB signaling after 20 to 24 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM633252(Preparation of 2-[(R)-3-decanoyloxytetradecanoylam...)
Affinity DataEC50:  41nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM633252(Preparation of 2-[(R)-3-decanoyloxytetradecanoylam...)
Affinity DataEC50:  64nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM633255(GLA | Glycopyranoside Lipid A | MPLA | Monophospho...)
Affinity DataEC50:  152nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50011382(CHEMBL3261034)
Affinity DataEC50:  390nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50250439(CHEMBL4068003)
Affinity DataEC50:  430nMAssay Description:Agonist activity at human TLR4 expressed in HEK293 blue cells assessed as induction of NF-kappaB activation-mediated SEAP production after 20 to 24 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50011377(CHEMBL3261029)
Affinity DataEC50:  500nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50011379(CHEMBL3261031)
Affinity DataEC50:  630nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50011380(CHEMBL3261032)
Affinity DataEC50:  630nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50011383(CHEMBL3261035)
Affinity DataEC50:  630nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50011378(CHEMBL3261030)
Affinity DataEC50:  790nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50011370(CHEMBL3261022)
Affinity DataEC50:  790nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50011402(CHEMBL3261254)
Affinity DataEC50:  790nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50011468(CHEMBL3261020)
Affinity DataEC50:  790nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50250439(CHEMBL4068003)
Affinity DataEC50:  820nMAssay Description:Agonist activity at mouse TLR4 expressed in HEK293 blue cells assessed as induction of NF-kappaB activation-mediated SEAP production after 20 to 24 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50250434(CHEMBL4103142)
Affinity DataEC50:  920nMAssay Description:Agonist activity at human TLR4 expressed in HEK293 blue cells assessed as induction of NF-kappaB activation-mediated SEAP production after 20 to 24 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50011374(CHEMBL3261026)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50011403(CHEMBL3261255)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50011467(CHEMBL3261019)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50011385(CHEMBL3261037)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50011384(CHEMBL3261036)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50011390(CHEMBL3261247)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50011372(CHEMBL3261024)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50011371(CHEMBL3261023)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50250434(CHEMBL4103142)
Affinity DataEC50:  2.01E+3nMAssay Description:Agonist activity at mouse TLR4 expressed in HEK293 blue cells assessed as induction of NF-kappaB activation-mediated SEAP production after 20 to 24 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50250413(CHEMBL4078865)
Affinity DataEC50:  2.12E+3nMAssay Description:Agonist activity at human TLR4 expressed in HEK293 blue cells assessed as induction of NF-kappaB activation-mediated SEAP production after 20 to 24 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50250417(CHEMBL4101433)
Affinity DataEC50:  2.45E+3nMAssay Description:Agonist activity at mouse TLR4 expressed in HEK293 blue cells assessed as induction of NF-kappaB activation-mediated SEAP production after 20 to 24 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50011389(CHEMBL3261246)
Affinity DataEC50:  2.50E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50011404(CHEMBL3261256)
Affinity DataEC50:  2.50E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50250418(CHEMBL4073017)
Affinity DataEC50:  2.51E+3nMAssay Description:Agonist activity at mouse TLR4 expressed in HEK293 blue cells assessed as induction of NF-kappaB activation-mediated SEAP production after 20 to 24 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50250413(CHEMBL4078865)
Affinity DataEC50:  2.58E+3nMAssay Description:Agonist activity at mouse TLR4 expressed in HEK293 blue cells assessed as induction of NF-kappaB activation-mediated SEAP production after 20 to 24 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50250415(CHEMBL4065290)
Affinity DataEC50:  2.74E+3nMAssay Description:Agonist activity at mouse TLR4 expressed in HEK293 blue cells assessed as induction of NF-kappaB activation-mediated SEAP production after 20 to 24 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50250409(CHEMBL4074812)
Affinity DataEC50:  2.83E+3nMAssay Description:Agonist activity at mouse TLR4 expressed in HEK293 blue cells assessed as induction of NF-kappaB activation-mediated SEAP production after 20 to 24 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50011392(CHEMBL3261249)
Affinity DataEC50:  3.10E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50011391(CHEMBL3261248)
Affinity DataEC50:  3.10E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50011463(CHEMBL3261013)
Affinity DataEC50:  3.10E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50011413(CHEMBL3261011)
Affinity DataEC50:  3.10E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 4(Homo sapiens (Human))
University Of Natural Resources And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50011412(CHEMBL3261010)
Affinity DataEC50:  3.10E+3nMAssay Description:Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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