Compile Data Set for Download or QSAR
maximum 50k data
Found 22 of ec50 data for polymerid = 50006722,9650
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50430056(CHEMBL2336409 | SGI-1027)
Affinity DataEC50:  1.02E+4nMAssay Description:Inhibition of human His-DNMT1 using [methyl-3H]SAM as substrate after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50239292(CHEMBL4070549)
Affinity DataEC50:  1.60E+4nMAssay Description:Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA dup...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£

Curated by ChEMBL
LigandPNGBDBM50239291(CHEMBL4091463)
Affinity DataEC50:  2.00E+4nMAssay Description:Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA dup...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£

Curated by ChEMBL
LigandPNGBDBM50239285(CHEMBL4096869)
Affinity DataEC50:  2.40E+4nMAssay Description:Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA dup...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£

Curated by ChEMBL
LigandPNGBDBM50239288(CHEMBL4097685)
Affinity DataEC50:  2.60E+4nMAssay Description:Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA dup...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£

Curated by ChEMBL
LigandPNGBDBM50239289(CHEMBL4096752)
Affinity DataEC50:  2.70E+4nMAssay Description:Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA dup...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£

Curated by ChEMBL
LigandPNGBDBM50239293(CHEMBL4076088)
Affinity DataEC50:  3.00E+4nMAssay Description:Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA dup...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£

Curated by ChEMBL
LigandPNGBDBM50239286(CHEMBL4084601)
Affinity DataEC50:  3.20E+4nMAssay Description:Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA dup...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£

Curated by ChEMBL
LigandPNGBDBM50239284(CHEMBL4096360)
Affinity DataEC50:  4.60E+4nMAssay Description:Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA dup...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£

Curated by ChEMBL
LigandPNGBDBM50239287(CHEMBL4100095)
Affinity DataEC50:  7.30E+4nMAssay Description:Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA dup...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£

Curated by ChEMBL
LigandPNGBDBM50506776(CHEMBL4442279)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£

Curated by ChEMBL
LigandPNGBDBM50506774(CHEMBL4470149)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£

Curated by ChEMBL
LigandPNGBDBM50506782(CHEMBL4461581)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£

Curated by ChEMBL
LigandPNGBDBM50506783(CHEMBL4582042)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£

Curated by ChEMBL
LigandPNGBDBM50239290(CHEMBL4099197)
Affinity DataEC50:  1.00E+5nMAssay Description:Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA dup...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£

Curated by ChEMBL
LigandPNGBDBM50506785(CHEMBL4537137)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£

Curated by ChEMBL
LigandPNGBDBM50506786(CHEMBL4469152)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£

Curated by ChEMBL
LigandPNGBDBM50506787(CHEMBL4558658)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£

Curated by ChEMBL
LigandPNGBDBM50506789(CHEMBL4470318)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£

Curated by ChEMBL
LigandPNGBDBM50506788(CHEMBL4526979)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£

Curated by ChEMBL
LigandPNGBDBM50506790(CHEMBL4574840)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Unit£

Curated by ChEMBL
LigandPNGBDBM50506784(CHEMBL4527662)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of recombinant human DNMT1 using biotinylated DNA duplex as substrate measured after 2 hrs in presence of Adomet/[methyl-3H]Adomet by topc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed