Compile Data Set for Download or QSAR
maximum 50k data
Found 409 of ic50 data for polymerid = 10670
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50032771((4aR,6aR,10S)-7-(1,5-Dimethyl-hexyl)-1,4a,6a,10-te...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human Steroid 5-alpha-reductase type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50037933((4aR,6aR,10R)-7-(1,5-Dimethyl-hexyl)-1,4a,6a,10-te...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of type 1 steroid-5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50368906(CHEMBL25448 | MK-386)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of recombinant human Steroid 5-alpha-reductase type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50368906(CHEMBL25448 | MK-386)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of type 1 steroid-5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50368906(CHEMBL25448 | MK-386)
Affinity DataIC50:  0.900nMAssay Description:Inhibitory concentration was tested on human 5-alpha reductase 1 isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50031876((4aR,6aS,7S)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of recombinant Steroid 5-alpha-reductase type I was evaluated as binding affinity of the compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50034137(CHEMBL275153 | N-Pentyl-N-((4aR,6aS,7S,11aR)-1,4a,...)
Affinity DataIC50:  0.910nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50037925((4aR,6aR,10S)-7-(1,5-Dimethyl-hexyl)-4a,6a,10-trim...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of type 1 steroid-5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50037912((4aR,6aR)-7-(1,5-Dimethyl-hexyl)-1,4a,6a-trimethyl...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of type 1 steroid-5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50039320((4aR,6aS,7S)-1,4a,6a-Trimethyl-2-oxo-hexadecahydro...)
Affinity DataIC50:  1.70nMAssay Description:Inhibitory concentration was tested on human 5-alpha reductase 1 isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50057458((4aR,6aR,7R)-7-(1,5-Dimethyl-hexyl)-1,4a,6a-trimet...)
Affinity DataIC50:  1.70nMAssay Description:Inhibitory concentration was tested on human 5-alpha reductase 1 isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50034151(CHEMBL280015 | Pentanoic acid pentyl-((4aR,6aS,7S,...)
Affinity DataIC50:  1.80nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50037911((4aR,6aR,10S)-7-(1,5-Dimethyl-hexyl)-1,4a,6a,10-te...)
Affinity DataIC50:  2nMAssay Description:Inhibition of type 1 steroid-5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50034161(CHEMBL17245 | N-(4-Methoxy-phenyl)-N-((4aR,6aS,7S,...)
Affinity DataIC50:  2.10nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50034134(CHEMBL17222 | N-(3-Methyl-butyl)-N-((4aR,6aS,7S,11...)
Affinity DataIC50:  2.20nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50368782(Bexlosteride | CHEMBL24955 | LY-191704)
Affinity DataIC50:  2.30nMAssay Description:Inhibitory activity against Steroid 5-alpha-reductase type I in human scalp homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50034142(CHEMBL16863 | N-(3,3-Dimethyl-butyl)-N-((4aR,6aS,7...)
Affinity DataIC50:  2.40nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50057487((4aR,6aS,7S)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7...)
Affinity DataIC50:  2.40nMAssay Description:Inhibitory concentration was tested on human 5-alpha reductase 1 isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50034135(5-Bromo-pentanoic acid pentyl-((4aR,6aS,7S,11aR)-1...)
Affinity DataIC50:  2.40nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50037916((4aR,6aR,10R)-7-(1,5-Dimethyl-hexyl)-4a,6a,10-trim...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of type 1 steroid-5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50037920((4aR,6aR,10S)-7-(1,5-Dimethyl-hexyl)-4a,6a,10-trim...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of type 1 steroid-5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50037923((4aR,6aR)-7-(1,5-Dimethyl-hexyl)-4a,6a-dimethyl-he...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of type 1 steroid-5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50037913((4aR,6aR,10S)-7-(1,5-Dimethyl-hexyl)-10-ethyl-4a,6...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of type 1 steroid-5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50034157(CHEMBL276320 | N-Phenyl-N-((4aR,6aS,7S,11aR)-1,4a,...)
Affinity DataIC50:  2.90nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50057477(4-(3-{3-[(4-Isobutyl-benzyl)-(4-isobutyl-phenyl)-a...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibitory activity against human Steroid 5-alpha-reductase type 1 in COS-1 cells was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50034143(CHEMBL277053 | N-Butyl-N-((4aR,6aS,7S,11aR)-1,4a,6...)
Affinity DataIC50:  3.10nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50034141(CHEMBL16784 | N-Pentyl-N-((4aR,6aS,7S,11aR)-1,4a,6...)
Affinity DataIC50:  3.20nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50057454((4aR,6aR,7R,10S)-7-(1,5-Dimethyl-hexyl)-1-ethyl-4a...)
Affinity DataIC50:  3.30nMAssay Description:Inhibitory concentration was tested on human 5-alpha reductase 1 isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50034159(CHEMBL278490 | N-Pentyl-N-((4aR,6aS,7S,11aR)-1,4a,...)
Affinity DataIC50:  3.30nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50037922((4aR,6aR,10S)-7-(1,5-Dimethyl-hexyl)-1-ethyl-4a,6a...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of type 1 steroid-5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50070046((4aR,10bR)-4,10b-Dimethyl-8-((E)-2-quinolin-3-yl-v...)
Affinity DataIC50:  3.40nMAssay Description:Inhibitory activity against Steroid 5-alpha-reductase type 1 enzyme based on the conversion of [3H]-T to [3H]-DHT in nuclear membrane preparations fr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50517880(CHEMBL4569322)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of human type 1 5alpha reductaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50340481(Avodart | CHEMBL1200969 | DUTASTERIDE | GG-745 | G...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human type 1 5alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50034147((4aR,6aS,7S,11aR)-1,4a,6a-Trimethyl-2-oxo-hexadeca...)
Affinity DataIC50:  4.10nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50037934((4aR,6aR)-7-(1,5-Dimethyl-hexyl)-1,4a,6a-trimethyl...)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of type 1 steroid-5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50034130(CHEMBL17194 | N-Pentyl-N-((4aR,6aS,7S,11aR)-1,4a,6...)
Affinity DataIC50:  4.60nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50037932((4aR,6aR)-7-(1,5-Dimethyl-hexyl)-4a,6a-dimethyl-1,...)
Affinity DataIC50:  5nMAssay Description:Inhibition of type 1 steroid-5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50034132(CHEMBL274276 | N-Propyl-N-((4aR,6aS,7S,11aR)-1,4a,...)
Affinity DataIC50:  5.10nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50034150(CHEMBL16700 | N-(4-Methoxy-phenyl)-N-((4aR,6aS,7S,...)
Affinity DataIC50:  5.40nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50057478((4aR,6aS,7S)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7...)
Affinity DataIC50:  5.60nMAssay Description:Inhibitory concentration was tested on human 5-alpha reductase 1 isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50032784((4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,...)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of recombinant human Steroid 5-alpha-reductase type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50034140(CHEMBL276527 | N-Benzyl-N-((4aR,6aS,7S,11aR)-1,4a,...)
Affinity DataIC50:  5.60nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50037915((4aR,6aR,10S)-7-(1,5-Dimethyl-hexyl)-10-ethyl-1,4a...)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of type 1 steroid-5-alpha-reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50092485(4-methyl-8-chloro-1,2,5,6-tetrahydro pyrido[1,2-a]...)
Affinity DataIC50:  5.80nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50032759((4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,...)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of recombinant human Steroid 5-alpha-reductase type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50070049((4aR,10bR)-4,10b-Dimethyl-8-((Z)-styryl)-1,4,4a,5,...)
Affinity DataIC50:  6nMAssay Description:Inhibitory activity against Steroid 5-alpha-reductase type I enzyme based on the conversion of [3H]-T to [3H]-DHT in nuclear membrane preparations fr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50032787((4aR,6aS)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,...)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of recombinant human Steroid 5-alpha-reductase type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50034139(CHEMBL16690 | N-Isobutyl-N-((4aR,6aS,7S,11aR)-1,4a...)
Affinity DataIC50:  7.30nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50034154(CHEMBL17506 | N-Hexyl-N-((4aR,6aS,7S,11aR)-1,4a,6a...)
Affinity DataIC50:  7.30nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50092485(4-methyl-8-chloro-1,2,5,6-tetrahydro pyrido[1,2-a]...)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of recombinant steroid 5-alpha-reductase type I expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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