TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: >130nMAssay Description:Compound was tested for inhibition of human activated protein C (APC)More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: >170nMAssay Description:Compound was tested for inhibition of human activated protein C (APC)More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: >450nMAssay Description:Compound was tested for inhibition of human activated protein C (APC)More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 470nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 670nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 710nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 820nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: >870nMAssay Description:Compound was tested for inhibition of human activated protein C (APC)More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 920nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 980nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 2.04E+3nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Tested in vitro for the inhibitory activity against activated protein C (APC)More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 3.83E+3nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory activity against activated protein C (aPC)More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 6.56E+3nMAssay Description:Inhibitory activity of the compound against activated protein C (APC)More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 9.08E+3nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 9.28E+3nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity of the compound against activated protein C was determinedMore data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity of the compound against activated protein C was determinedMore data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration of compound was determined against activated protein C (aPC)More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration of compound was determined against activated protein C (aPC)More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration of compound was determined against activated protein CMore data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration of compound was determined against activated protein C (aPC)More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibitory activity of the compound against activated protein C was determinedMore data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of activated anticoagulant protein C (unknown origin)More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of activated anticoagulant protein C (unknown origin)More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of activated anticoagulant protein C (unknown origin)More data for this Ligand-Target Pair