Compile Data Set for Download or QSAR
maximum 50k data
Found 1101 of ic50 data for polymerid = 254,5111
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  0.0244nMAssay Description:Enzyme activity using acetylcholinesterase (AChE) and butyrylcholinesterase (BChE).More data for this Ligand-Target Pair
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM86769(Nicotinamide hydrochloride analog, 6b)
Affinity DataIC50:  0.645nMAssay Description:Enzyme activity using acetylcholinesterase (AChE) and butyrylcholinesterase (BChE).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM8986(7-chloro-1,2,3,4-tetrahydroacridin-9-amine | Tacri...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of (BChE) Butyrylcholinesterase of horse serumMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM86771(Nicotinamide hydrochloride analog, 6d)
Affinity DataIC50:  0.811nMAssay Description:Enzyme activity using acetylcholinesterase (AChE) and butyrylcholinesterase (BChE).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM9007(7-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-heptanoic...)
Affinity DataIC50:  0.950nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM227587(3-fluoro-N-[4-(1,2,3,4-tetrahydroacridin-9-ylamino...)
Affinity DataIC50:  1.02nMpH: 7.4 T: 2°CAssay Description:The test was run as described in the following procedure: stock solution of the test compounds was diluted in phosphate buffer pH 7.4 to give final c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM86770(Nicotinamide hydrochloride analog, 6c)
Affinity DataIC50:  1.13nMAssay Description:Enzyme activity using acetylcholinesterase (AChE) and butyrylcholinesterase (BChE).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM50060470(10-azatetracyclo[10.2.1.02,11.04,9]pentadeca-2,4,6...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of (BChE) Butyrylcholinesterase of horse serumMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM227584(2-Fluoro-N-[4-(1,2,3,4-tetrahydroacridin-9-ylamino...)
Affinity DataIC50:  1.39nMpH: 7.4 T: 2°CAssay Description:The test was run as described in the following procedure: stock solution of the test compounds was diluted in phosphate buffer pH 7.4 to give final c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM9426(CHEMBL258928 | Heterodimeric Tacrine-Based Inhibit...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of equine BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM86768(Nicotinamide hydrochloride analog, 6a)
Affinity DataIC50:  1.45nMAssay Description:Enzyme activity using acetylcholinesterase (AChE) and butyrylcholinesterase (BChE).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Mus musculus (Mouse))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50312905(3alpha,8-dimethyl-1-phenethyl-1,2,3,3alpha,8,8alph...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM9013(6-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-hexanoic ...)
Affinity DataIC50:  2nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM9014(7-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-heptanoic...)
Affinity DataIC50:  2.5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM50333767(CHEMBL1644288 | N1-(1,2,3,4-Tetrahydroacridin-9-yl...)
Affinity DataIC50:  2.59nMAssay Description:Inhibition of equine BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM50333763(CHEMBL1644292 | N1-(3,4-Dimethoxybenzyl)-N6-(1,2,3...)
Affinity DataIC50:  2.68nMAssay Description:Inhibition of equine BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM50333765(CHEMBL1644290 | N1-(1,2,3,4-Tetrahydroacridin-9-yl...)
Affinity DataIC50:  3.38nMAssay Description:Inhibition of equine BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM9018(6-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-hexanoic ...)
Affinity DataIC50:  3.5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM50333766(CHEMBL1644289 | N1-(1,2,3,4-Tetrahydroacridin-9-yl...)
Affinity DataIC50:  3.55nMAssay Description:Inhibition of equine BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM227586(3-Fluoro-N-[3-(1,2,3,4-tetrahydroacridin-9-ylamino...)
Affinity DataIC50:  3.79nMpH: 7.4 T: 2°CAssay Description:The test was run as described in the following procedure: stock solution of the test compounds was diluted in phosphate buffer pH 7.4 to give final c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM50333764(CHEMBL1644291 | N1-(1,2,3,4-Tetrahydroacridin-9-yl...)
Affinity DataIC50:  4.73nMAssay Description:Inhibition of equine BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM227585(3-Fluoro-N-[2-(1,2,3,4-tetrahydroacridin-9-ylamino...)
Affinity DataIC50:  4.76nMpH: 7.4 T: 2°CAssay Description:The test was run as described in the following procedure: stock solution of the test compounds was diluted in phosphate buffer pH 7.4 to give final c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM50194097(CHEMBL213609 | N,N'-bis[2,3-dihydropyrrolo[2,1-b]q...)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of horse serum BChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Mus musculus (Mouse))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50467895(CHEMBL4280262)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of BuChE in Swiss Webster mouse whole blood serum using butyrylthiocholine iodide as substrate preincubated for 10 mins followed substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM50377432(CHEMBL258927)
Affinity DataIC50:  5nMAssay Description:Inhibition of equine BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of equine BChE by Ellman's assayMore data for this Ligand-Target Pair
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of BuChE from equine serumMore data for this Ligand-Target Pair
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM50333771(CHEMBL1644284 | N1-((7-Methoxybenzo[d][1,3]dioxol-...)
Affinity DataIC50:  5.19nMAssay Description:Inhibition of equine BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  5.20nMpH: 8.0Assay Description:The inhibitory activity of the enzyme acetylcholinesterase (AChE) was evaluated by the Ellman method (Biochem. Pharmacol. 1961, 7, 88) using an elect...More data for this Ligand-Target Pair
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of (BChE) Butyrylcholinesterase of horse serumMore data for this Ligand-Target Pair
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM9008(6-(6-Chloro-1,2,3,4-tetrahydro-acridin-9-ylamino)-...)
Affinity DataIC50:  5.20nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM50377431(CHEMBL258744)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of equine BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM50333762(CHEMBL1644293 | N1-(3,4-Dimethoxybenzyl)-N7-(1,2,3...)
Affinity DataIC50:  5.51nMAssay Description:Inhibition of equine BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM50333761(CHEMBL1644294 | N1-(3,4-Dimethoxybenzyl)-N8-(1,2,3...)
Affinity DataIC50:  5.57nMAssay Description:Inhibition of equine BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM50333760(CHEMBL1644295 | N1-(3,4-Dimethoxybenzyl)-N9-(1,2,3...)
Affinity DataIC50:  5.67nMAssay Description:Inhibition of equine BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM50261344(CHEMBL466338 | N-(3-{[6-Chloro-2,3-dihydropyrrolo[...)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of equine serum BuChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  5.90nMpH: 8.0 T: 2°CAssay Description:This spectrophotometric assay is based on the reaction of 5,5-dithio-bis(2-nitrobenzoic)acid (DTNB) with thiocholine to yield a colored product. Sh...More data for this Ligand-Target Pair
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM50377436(CHEMBL255304)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of equine BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  6nMAssay Description:Compound was evaluated for the in vitro inhibition of the Butyrylcholinesterase from horse serumMore data for this Ligand-Target Pair
TargetCholinesterase(Mus musculus (Mouse))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50312902(3alpha,8-dimethyl-1-phenethyl-1,2,3,3alpha,8,8alph...)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM50377439(CHEMBL257126)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of equine BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM50377433(CHEMBL258926)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of equine BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM50273429(9-[N(delta)-propyl -delta-aminobutylamino]-1,2,3,4...)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of BuChE from equine serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM50273578(9-[Nbeta-(2'-(Nitrooxy)ethyl)-beta-aminoethylamino...)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of BuChE from equine serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM50194105(CHEMBL213850 | N,N'-bis[6,7,8,9-tetrahydro-11H-pyr...)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of horse serum BChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM227583(2-Fluoro-N-[3-(1,2,3,4-tetrahydroacridin-9-ylamino...)
Affinity DataIC50:  7.80nMpH: 7.4 T: 2°CAssay Description:The test was run as described in the following procedure: stock solution of the test compounds was diluted in phosphate buffer pH 7.4 to give final c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM8987(6-chloro-1,2,3,4-tetrahydroacridin-9-amine | 6-chl...)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of (BChE) Butyrylcholinesterase of horse serumMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM50333769(CHEMBL1644286 | N1-((7-Methoxybenzo[d][1,3]dioxol-...)
Affinity DataIC50:  7.94nMAssay Description:Inhibition of equine BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Medical University Of Lodz

LigandPNGBDBM50400030(CHEMBL2177713)
Affinity DataIC50:  8nMAssay Description:Inhibition of equine BuChE after 120 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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