Compile Data Set for Download or QSAR
maximum 50k data
Found 38 of ic50 data for polymerid = 2624
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24572((2R)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]heptan-2-...)
Affinity DataIC50:  100nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24573((2S,5E)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridec...)
Affinity DataIC50:  120nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24574((2R)-1-[(2S,3R)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)
Affinity DataIC50:  180nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24575((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]pentadeca...)
Affinity DataIC50:  210nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24569((1R)-1-{[(2S,3S)-3-ethyl-4-oxooxetan-2-yl]methyl}d...)
Affinity DataIC50:  230nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24570((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]hex-5-en-...)
Affinity DataIC50:  280nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24576((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]pentadeca...)
Affinity DataIC50:  290nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24571((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]heptan-2-...)
Affinity DataIC50:  300nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24577((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]-3-{[(4-m...)
Affinity DataIC50:  370nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24578((2S,5E)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridec...)
Affinity DataIC50:  400nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24579((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]pentadeca...)
Affinity DataIC50:  450nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24580((2S,5E)-6-(4-fluorophenyl)-1-[(2S,3S)-3-hexyl-4-ox...)
Affinity DataIC50:  500nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24581((2R)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]hex-5-en-...)
Affinity DataIC50:  500nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24582((2R)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]propan-2-...)
Affinity DataIC50:  520nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24583((2R,5E)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]hept-5...)
Affinity DataIC50:  680nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24569((1R)-1-{[(2S,3S)-3-ethyl-4-oxooxetan-2-yl]methyl}d...)
Affinity DataIC50:  790nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24585((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]hex-5-en-...)
Affinity DataIC50:  900nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24586((1R)-1-{[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]methyl}d...)
Affinity DataIC50:  1.02E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24587((2S,5E)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]hept-5...)
Affinity DataIC50:  1.04E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24567((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)
Affinity DataIC50:  1.35E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24588((1R)-1-{[(2S,3S)-3-butyl-4-oxooxetan-2-yl]methyl}d...)
Affinity DataIC50:  1.35E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24586((1R)-1-{[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]methyl}d...)
Affinity DataIC50:  1.72E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24590((2S)-1-[(2S,3S)-3-octyl-4-oxooxetan-2-yl]undecan-2...)
Affinity DataIC50:  3.00E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24591((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]pentadeca...)
Affinity DataIC50:  3.67E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24592((2R,5E)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]hept-5...)
Affinity DataIC50:  6.24E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24975((3S,4S)-1-(benzyloxy)-4-[(2S)-2-[(tert-butyldimeth...)
Affinity DataIC50:  8.60E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24593((2S)-1-[(2R,3R)-3-hexyl-4-oxooxetan-2-yl]pentadeca...)
Affinity DataIC50:  9.74E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24594((2S)-1-[(2S,3S)-3-methyl-4-oxooxetan-2-yl]tridecan...)
Affinity DataIC50:  1.08E+4nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24595((2S,5E)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]hept-5...)
Affinity DataIC50:  1.35E+4nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24980((2R)-1-[(2R,3R)-1-(benzyloxy)-3-hexyl-4-oxoazetidi...)
Affinity DataIC50:  3.92E+4nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24596((2S)-1-[(2R,3R)-3-methyl-4-oxooxetan-2-yl]tridecan...)
Affinity DataIC50:  4.51E+4nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24981((3S,4S)-1-(benzyloxy)-3-hexyl-4-[(2S)-2-hydroxyhep...)
Affinity DataIC50:  5.05E+4nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24982((2S)-1-[(2S,3S)-1-(benzyloxy)-3-hexyl-4-oxoazetidi...)
Affinity DataIC50:  5.82E+4nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24978((3R,4R)-1-(benzyloxy)-3-hexyl-4-[(2R)-2-hydroxytri...)
Affinity DataIC50:  6.12E+4nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24983((3S,4S)-3-hexyl-4-[(2S)-2-hydroxyheptyl]azetidin-2...)
Affinity DataIC50:  6.76E+4nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24979((2S)-1-[(2S,3S)-1-(benzyloxy)-3-hexyl-4-oxoazetidi...)
Affinity DataIC50:  6.89E+4nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24977((3S,4S)-1-(benzyloxy)-3-hexyl-4-[(2S)-2-hydroxytri...)
Affinity DataIC50:  8.68E+4nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24976((3R,4R)-1-(benzyloxy)-4-[(2R)-2-[(tert-butyldimeth...)
Affinity DataIC50:  9.74E+4nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed