Compile Data Set for Download or QSAR
maximum 50k data
Found 47 of ic50 data for polymerid = 3987
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM109236(WEHI-539)
Affinity DataIC50:  1.10nMpH: 7.4 T: 2°CAssay Description:Each 384-well plate was prepared with 4.75 µL of working assay buffer (50 mM HEPES, 10 mM DTT, 100 mM NaCl, 0.05% Tween029 and 0.1 mg/mL casein,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM109235((E)-2-(8-(2-(Benzo[d]thiazol-2-yl)hydrazono)-5,6,7...)
Affinity DataIC50:  1.5nMpH: 7.4 T: 2°CAssay Description:Each 384-well plate was prepared with 4.75 µL of working assay buffer (50 mM HEPES, 10 mM DTT, 100 mM NaCl, 0.05% Tween029 and 0.1 mg/mL casein,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM361589(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4- ((6-(...)
Affinity DataIC50:  4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataIC50:  5nMpH: 7.4 T: 2°CAssay Description:Each 384-well plate was prepared with 4.75 µL of working assay buffer (50 mM HEPES, 10 mM DTT, 100 mM NaCl, 0.05% Tween029 and 0.1 mg/mL casein,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM361577((S)-N-((4-(((1,4-dioxan-2-yl)methyl)amino)-3- nitr...)
Affinity DataIC50:  5.90nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM109234(6-(8-(2-(Benzo[d]thiazol-2-yl)hydrazono)-5,6,7,8-t...)
Affinity DataIC50:  6.20nMpH: 7.4 T: 2°CAssay Description:Each 384-well plate was prepared with 4.75 µL of working assay buffer (50 mM HEPES, 10 mM DTT, 100 mM NaCl, 0.05% Tween029 and 0.1 mg/mL casein,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM361579((R)-N-((4-(((1,4-dioxan-2-yl)methyl)amino)-3- nitr...)
Affinity DataIC50:  6.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM109236(WEHI-539)
Affinity DataIC50:  7.10nM Kd:  1.40nMpH: 7.4Assay Description:The protocols for tight and weak binders were described in Biacore S51 assay set-up with a flow rate of 30 µL/min. For His-Bcl-2 protein assays...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM361590(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4- ((6-(...)
Affinity DataIC50:  7.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM361575(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((6-(4...)
Affinity DataIC50:  8.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM361591(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4- ((6-(...)
Affinity DataIC50:  8.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM361572((R)-N-((4-(((1,4-dioxan-2-yl)methyl)amino)-3- nitr...)
Affinity DataIC50:  9.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM361592(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4- ((6-(...)
Affinity DataIC50:  9.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM361573(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((6-(4...)
Affinity DataIC50:  10.6nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM361593(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4- ((6-(...)
Affinity DataIC50:  12nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM109233(2-(8-(2-(Benzothiazol-2-yl)hydrazono)-5,6,7,8-tetr...)
Affinity DataIC50:  13nMpH: 7.4Assay Description:The protocols for tight and weak binders were described in Biacore S51 assay set-up with a flow rate of 30 µL/min. For His-Bcl-2 protein assays...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM361588(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4- ((6-(...)
Affinity DataIC50:  13.1nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM361574(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((6-(4...)
Affinity DataIC50:  13.7nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataIC50:  14nMpH: 7.4Assay Description:The protocols for tight and weak binders were described in Biacore S51 assay set-up with a flow rate of 30 µL/min. For His-Bcl-2 protein assays...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM361581(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((6-(4...)
Affinity DataIC50:  14nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM361576((R)-N-((4-(((1,4-dioxan-2-yl)methyl)amino)-3- nitr...)
Affinity DataIC50:  14nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM361584((R)-N-((4-(((1,4-dioxan-2-yl)methyl)amino)-3- nitr...)
Affinity DataIC50:  14.8nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM361578(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(1-((6-(4...)
Affinity DataIC50:  15.7nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM361585(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4- ((6-(...)
Affinity DataIC50:  19.2nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM109232(6-(8-(2-(Benzothiazol-2-yl)hydrazono)-5,6,7,8-tetr...)
Affinity DataIC50:  20nMpH: 7.4Assay Description:The protocols for tight and weak binders were described in Biacore S51 assay set-up with a flow rate of 30 µL/min. For His-Bcl-2 protein assays...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM361580(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(1-((6-(4...)
Affinity DataIC50:  20.6nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM361586(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4- ((6-(...)
Affinity DataIC50:  20.7nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM109232(6-(8-(2-(Benzothiazol-2-yl)hydrazono)-5,6,7,8-tetr...)
Affinity DataIC50:  23nMpH: 7.4 T: 2°CAssay Description:Each 384-well plate was prepared with 4.75 µL of working assay buffer (50 mM HEPES, 10 mM DTT, 100 mM NaCl, 0.05% Tween029 and 0.1 mg/mL casein,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM109233(2-(8-(2-(Benzothiazol-2-yl)hydrazono)-5,6,7,8-tetr...)
Affinity DataIC50:  24nMpH: 7.4 T: 2°CAssay Description:Each 384-well plate was prepared with 4.75 µL of working assay buffer (50 mM HEPES, 10 mM DTT, 100 mM NaCl, 0.05% Tween029 and 0.1 mg/mL casein,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM218795(130E7 | Ac-λIAQELRRIGDEFNAYYARR-NH2)
Affinity DataIC50:  46.5nMAssay Description:One hundred microliters of a 600 ng/mL solution of biotin-BID (Biotin-lc-EDIIRNIARHLAQVGDSMDR-NH2, where lc indicates a hydrocarbon chain of six meth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM361587(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4- ((6-(...)
Affinity DataIC50:  67.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM361582(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((6-(4...)
Affinity DataIC50:  77.8nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM361583(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(1-((6-(4...)
Affinity DataIC50:  139nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM218796(130D11 | Ac-λAQELR(Xi)IGD(Xi+4)FNAYYARR-NH2)
Affinity DataIC50:  220nMAssay Description:One hundred microliters of a 600 ng/mL solution of biotin-BID (Biotin-lc-EDIIRNIARHLAQVGDSMDR-NH2, where lc indicates a hydrocarbon chain of six meth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM85274(BI-21C6)
Affinity DataIC50:  500nMAssay Description:In order to figure whether these compounds were capable of displacing the interactions between Bci-XL and it's pro-apoptotic counterparts, it was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM109231(N-(3-(5-(1-(2-(Benzo[d]thiazol-2-yl)hydrazono)ethy...)
Affinity DataIC50:  770nMpH: 7.4 T: 2°CAssay Description:Each 384-well plate was prepared with 4.75 µL of working assay buffer (50 mM HEPES, 10 mM DTT, 100 mM NaCl, 0.05% Tween029 and 0.1 mg/mL casein,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM218791(Ac-CATQLRRFGDKLN-NH2 | hNOXAs)
Affinity DataIC50: >1.00E+3nMAssay Description:One hundred microliters of a 600 ng/mL solution of biotin-BID (Biotin-lc-EDIIRNIARHLAQVGDSMDR-NH2, where lc indicates a hydrocarbon chain of six meth...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM218790(λ_hNOXA | Ac-λATQLRRFGDKLNFRQKLLN-NH2)
Affinity DataIC50: >1.00E+3nMAssay Description:One hundred microliters of a 600 ng/mL solution of biotin-BID (Biotin-lc-EDIIRNIARHLAQVGDSMDR-NH2, where lc indicates a hydrocarbon chain of six meth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM218789(Ac-hCATQLRRFGDKLNFRQKLLN-NH2 | homo_hNOXA)
Affinity DataIC50: >1.00E+3nMAssay Description:One hundred microliters of a 600 ng/mL solution of biotin-BID (Biotin-lc-EDIIRNIARHLAQVGDSMDR-NH2, where lc indicates a hydrocarbon chain of six meth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM218788(Ac-CATQLRRFGDKLNFRQKLLN-NH2 | hNOXA)
Affinity DataIC50: >1.00E+3nMAssay Description:One hundred microliters of a 600 ng/mL solution of biotin-BID (Biotin-lc-EDIIRNIARHLAQVGDSMDR-NH2, where lc indicates a hydrocarbon chain of six meth...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM60828(ABT-199 | BDBM189459 | US10213433, Compound 5 | US...)
Affinity DataIC50: >1.00E+3nMAssay Description:One hundred microliters of a 600 ng/mL solution of biotin-BID (Biotin-lc-EDIIRNIARHLAQVGDSMDR-NH2, where lc indicates a hydrocarbon chain of six meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM218792(Ac-AELPPEFAAQLRKIGDKVYC-NH2 | NOXA A)
Affinity DataIC50: >1.00E+3nMAssay Description:One hundred microliters of a 600 ng/mL solution of biotin-BID (Biotin-lc-EDIIRNIARHLAQVGDSMDR-NH2, where lc indicates a hydrocarbon chain of six meth...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM218793(Ac-PADLKDECAQLRRIGDKVNL-NH2 | NOXA B)
Affinity DataIC50: >1.00E+3nMAssay Description:One hundred microliters of a 600 ng/mL solution of biotin-BID (Biotin-lc-EDIIRNIARHLAQVGDSMDR-NH2, where lc indicates a hydrocarbon chain of six meth...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM50436643(3-(5-(1-(2-(Benzo[d]thiazol-2-yl)hydrazono)ethyl)f...)
Affinity DataIC50:  2.20E+3nMpH: 7.4 T: 2°CAssay Description:Each 384-well plate was prepared with 4.75 µL of working assay buffer (50 mM HEPES, 10 mM DTT, 100 mM NaCl, 0.05% Tween029 and 0.1 mg/mL casein,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM85272(BI-21C4)
Affinity DataIC50:  3.30E+3nMAssay Description:In order to figure whether these compounds were capable of displacing the interactions between Bci-XL and it's pro-apoptotic counterparts, it was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM85273(BI-21C5)
Affinity DataIC50:  5.10E+3nM Kd:  1.98E+4nMAssay Description:In order to figure whether these compounds were capable of displacing the interactions between Bci-XL and it's pro-apoptotic counterparts, it was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research

LigandPNGBDBM85275(BI-21C7)
Affinity DataIC50:  5.70E+3nMAssay Description:In order to figure whether these compounds were capable of displacing the interactions between Bci-XL and it's pro-apoptotic counterparts, it was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed