Found 33 of ic50 data for polymerid = 50000161,50004919 TargetATP-binding cassette sub-family C member 8(Homo sapiens (Human))
University Of Mainz
Curated by ChEMBL
University Of Mainz
Curated by ChEMBL
Affinity DataIC50: 106nMAssay Description:In vitro displacement of [3H]-glibenclamide (IC50=0.61) from COS-1 cells expressing Sulfonylurea receptor 1 (SUR-1)More data for this Ligand-Target Pair
3D Structure (crystal)TargetATP-binding cassette sub-family C member 8(Homo sapiens (Human))
University Of Mainz
Curated by ChEMBL
University Of Mainz
Curated by ChEMBL
Affinity DataIC50: 163nMAssay Description:In vitro displacement of [3H]-glibenclamide (IC50=0.61) from COS-1 cells expressing Sulfonylurea receptor 1 (SUR-1)More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8(Homo sapiens (Human))
University Of Mainz
Curated by ChEMBL
University Of Mainz
Curated by ChEMBL
Affinity DataIC50: 281nMAssay Description:In vitro displacement of [3H]-glibenclamide (IC50=0.61) from COS-1 cells expressing Sulfonylurea receptor 1 (SUR-1)More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair
Affinity DataIC50: 520nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair
Affinity DataIC50: 620nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair
Affinity DataIC50: 760nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair
Affinity DataIC50: 1.41E+3nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair
Affinity DataIC50: 1.67E+3nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair
Affinity DataIC50: 1.73E+3nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair
Affinity DataIC50: 1.75E+3nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair
Affinity DataIC50: 1.81E+3nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair
Affinity DataIC50: 2.05E+3nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair
Affinity DataIC50: 2.98E+3nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair
Affinity DataIC50: 3.03E+3nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair
Affinity DataIC50: 3.58E+3nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair
Affinity DataIC50: 3.78E+3nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair
Affinity DataIC50: 4.93E+3nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair
Affinity DataIC50: 6.31E+3nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair
Affinity DataIC50: 8.67E+3nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair
Affinity DataIC50: 2.65E+4nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair
Affinity DataIC50: 3.75E+4nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair
Affinity DataIC50: 3.89E+4nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretionMore data for this Ligand-Target Pair
