Compile Data Set for Download or QSAR
maximum 50k data
Found 432 of ic50 data for polymerid = 50000279,50004158
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356075(CHEMBL1911818)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of GCS activity in human A549 cells assessed as amount of GM1 on the cell membrane after 72 hrs by FL-CTB-based fluorescent microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM339792(US10202340, Example 11)
Affinity DataIC50:  0.840nMAssay Description:)Inhibition of GlcCer production in MDCKII cells stably expressing human MDR1 (obtained from The Netherlands Cancer Institute).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM339793(US10202340, Example 12)
Affinity DataIC50:  0.870nMAssay Description:Inhibition of GlcCer production in whole wild-type MDCKII cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM339792(US10202340, Example 11)
Affinity DataIC50:  1nMAssay Description:Inhibition of GlcCer production in whole wild-type MDCKII cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356076(CHEMBL1911817)
Affinity DataIC50:  1nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356075(CHEMBL1911818)
Affinity DataIC50:  1nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50602025(CHEMBL5181454)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of mouse GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356091(CHEMBL1911679)
Affinity DataIC50:  2nMAssay Description:Inhibition of GCS activity in human A549 cells assessed as amount of GM1 on the cell membrane after 72 hrs by FL-CTB-based fluorescent microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356090(CHEMBL1911678)
Affinity DataIC50:  2nMAssay Description:Inhibition of GCS in human A549 cells assessed as decrease in GM1 synthesis after 72 hrs by Fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356091(CHEMBL1911679)
Affinity DataIC50:  2nMAssay Description:Inhibition of GCS in human A549 cells assessed as decrease in GM1 synthesis after 72 hrs by Fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356076(CHEMBL1911817)
Affinity DataIC50:  2nMAssay Description:Inhibition of GCS activity in human A549 cells assessed as amount of GM1 on the cell membrane after 72 hrs by FL-CTB-based fluorescent microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356077(CHEMBL1911816)
Affinity DataIC50:  2nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356078(CHEMBL1911815)
Affinity DataIC50:  2nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50394804(CHEMBL2163828)
Affinity DataIC50:  2nMAssay Description:Inhibition of GCS assessed as amount of UDP glucose after 3 hrs by Fluorometry analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356090(CHEMBL1911678)
Affinity DataIC50:  2nMAssay Description:Inhibition of GCS activity in human A549 cells assessed as amount of GM1 on the cell membrane after 72 hrs by FL-CTB-based fluorescent microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50394807(CHEMBL2163825)
Affinity DataIC50:  2nMAssay Description:Inhibition of GCS in human A549 cells assessed as decrease in GM1 synthesis after 72 hrs by Fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50394812(CHEMBL2163838)
Affinity DataIC50:  2nMAssay Description:Inhibition of GCS assessed as amount of UDP glucose after 3 hrs by Fluorometry analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50394820(CHEMBL2163829)
Affinity DataIC50:  2nMAssay Description:Inhibition of GCS assessed as amount of UDP glucose after 3 hrs by Fluorometry analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM339793(US10202340, Example 12)
Affinity DataIC50:  2.5nMAssay Description:)Inhibition of GlcCer production in MDCKII cells stably expressing human MDR1 (obtained from The Netherlands Cancer Institute).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50028257(CHEMBL3354637)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of glucosylceramide synthase (unknown origin) assessed as catabolism of NBD-glucosylceramideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356079(CHEMBL1911814)
Affinity DataIC50:  3nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50028217(CHEMBL3354037)
Affinity DataIC50:  3nMAssay Description:Inhibition of glucosylceramide synthase (unknown origin) assessed as catabolism of NBD-glucosylceramideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50028215(CHEMBL3354035)
Affinity DataIC50:  3nMAssay Description:Inhibition of glucosylceramide synthase (unknown origin) assessed as catabolism of NBD-glucosylceramideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50028206(CHEMBL3354024)
Affinity DataIC50:  3nMAssay Description:Inhibition of glucosylceramide synthase (unknown origin) assessed as catabolism of NBD-glucosylceramideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50028204(CHEMBL3354022)
Affinity DataIC50:  3nMAssay Description:Inhibition of glucosylceramide synthase (unknown origin) assessed as catabolism of NBD-glucosylceramideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50028255(CHEMBL3354635)
Affinity DataIC50:  3nMAssay Description:Inhibition of glucosylceramide synthase (unknown origin) assessed as catabolism of NBD-glucosylceramideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50028254(CHEMBL3354634)
Affinity DataIC50:  3nMAssay Description:Inhibition of glucosylceramide synthase (unknown origin) assessed as catabolism of NBD-glucosylceramideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM339782(US10202340, Example 1)
Affinity DataIC50:  3nMAssay Description:Inhibition of GlcCer production in whole wild-type MDCKII cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM339783(US10202340, Example 2)
Affinity DataIC50:  3nMAssay Description:Inhibition of GlcCer production in whole wild-type MDCKII cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50394809(CHEMBL2163823)
Affinity DataIC50:  3nMAssay Description:Inhibition of GCS assessed as amount of UDP glucose after 3 hrs by Fluorometry analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50394806(CHEMBL2163826)
Affinity DataIC50:  3nMAssay Description:Inhibition of GCS assessed as amount of UDP glucose after 3 hrs by Fluorometry analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50394805(CHEMBL2163827)
Affinity DataIC50:  3nMAssay Description:Inhibition of GCS assessed as amount of UDP glucose after 3 hrs by Fluorometry analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50394816(CHEMBL2163833)
Affinity DataIC50:  3nMAssay Description:Inhibition of GCS in human A549 cells assessed as decrease in GM1 synthesis after 72 hrs by Fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50602025(CHEMBL5181454)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of human GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50602022(CHEMBL5197585)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of mouse GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50394817(CHEMBL2163832)
Affinity DataIC50:  4nMAssay Description:Inhibition of GCS in human A549 cells assessed as decrease in GM1 synthesis after 72 hrs by Fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50394811(CHEMBL2163839)
Affinity DataIC50:  4nMAssay Description:Inhibition of GCS assessed as amount of UDP glucose after 3 hrs by Fluorometry analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356094(CHEMBL1911829)
Affinity DataIC50:  4nMAssay Description:Inhibition of GCS activity in human A549 cells assessed as amount of GM1 on the cell membrane after 72 hrs by FL-CTB-based fluorescent microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM339788(US10202340, Example 7)
Affinity DataIC50:  4nMAssay Description:Inhibition of GlcCer production in whole wild-type MDCKII cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50394807(CHEMBL2163825)
Affinity DataIC50:  4nMAssay Description:Inhibition of GCS assessed as amount of UDP glucose after 3 hrs by Fluorometry analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50602022(CHEMBL5197585)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of human GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM339784(US10202340, Example 3)
Affinity DataIC50:  5nMAssay Description:Inhibition of GlcCer production in whole wild-type MDCKII cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356094(CHEMBL1911829)
Affinity DataIC50:  5nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356066(CHEMBL1911827)
Affinity DataIC50:  5nMAssay Description:Inhibition of GCS activity in human A549 cells assessed as amount of GM1 on the cell membrane after 72 hrs by FL-CTB-based fluorescent microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50028256(CHEMBL3354636)
Affinity DataIC50:  5nMAssay Description:Inhibition of glucosylceramide synthase (unknown origin) assessed as catabolism of NBD-glucosylceramideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM339785(US10202340, Example 4)
Affinity DataIC50:  5nMAssay Description:Inhibition of GlcCer production in whole wild-type MDCKII cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50602024(CHEMBL5178033)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of mouse GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM367616(N-((1R,2R)-1-(3-chloro-4- cyclopropoxyphenyl)-1-hy...)
Affinity DataIC50:  5.5nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM367617(N-((1R,2R)-1-(4-cyclopropoxy-3- fluorophenyl)-1-hy...)
Affinity DataIC50:  5.5nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM367618(N-((1R,2R)-1-(8-fluoro-2,3- dihydrobenzo[b][1,4]di...)
Affinity DataIC50:  5.5nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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