Compile Data Set for Download or QSAR
maximum 50k data
Found 48 of ic50 data for polymerid = 50000933,50007401
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50239459(CHEMBL4074929)
Affinity DataIC50:  400nMAssay Description:In vitro inhibition of [3H]5-HT transporter uptake in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50239457(CHEMBL4071143)
Affinity DataIC50:  400nMAssay Description:Inhibition of human TMEM16B expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50239428(CHEMBL4104024)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human TMEM16B expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50239426(CHEMBL1444023)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human TMEM16B expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50239464(CHEMBL4085154)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human TMEM16B expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50239466(CHEMBL1299863)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of TMEM16B (unknown origin) expressed in FRT cells assessed as reduction of ATP-induced chloride conductance preincubated for 20 mins foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50239433(CHEMBL3134585)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human TMEM16B expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Mus musculus)
Korea University

Curated by ChEMBL
LigandPNGBDBM50556203(CHEMBL4791938)
Affinity DataIC50:  7.43E+3nMAssay Description:Inhibition of GFP-fused mouse ANO2 channel expressed in HEK293A cells assessed as inhibition of channel current amplitude at membrane potential of +8...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50594075(CHEMBL5186789)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of human ANO2 expressed in HEK293 cells incubated for 5 mins by whole cell patch clamp electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50503431(CHEMBL4471568 | US11274074, Example 3 [Chemical Fo...)
Affinity DataIC50:  1.24E+4nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50503431(CHEMBL4471568 | US11274074, Example 3 [Chemical Fo...)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibition of YFP-fused ANO2 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50239467(CHEMBL4086165)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human TMEM16B expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM542066(US11274074, Example 11 [Chemical Formula 15])
Affinity DataIC50:  1.31E+4nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAnoctamin-2(Mus musculus)
Korea University

Curated by ChEMBL
LigandPNGBDBM50556199(CHEMBL4747471)
Affinity DataIC50:  1.54E+4nMAssay Description:Inhibition of GFP-fused mouse ANO2 channel expressed in HEK293A cells assessed as inhibition of channel current amplitude at membrane potential of +8...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50239465(CHEMBL4080525 | US11274074, Control [Ani9])
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human TMEM16B expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50503440(CHEMBL4441034 | US11274074, Example 7 [Chemical Fo...)
Affinity DataIC50:  5.94E+4nMAssay Description:Inhibition of YFP-fused ANO2 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50503440(CHEMBL4441034 | US11274074, Example 7 [Chemical Fo...)
Affinity DataIC50:  5.94E+4nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50503442(CHEMBL4453660 | US11274074, Example 9 [Chemical Fo...)
Affinity DataIC50: >1.00E+5nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50503449(CHEMBL4517769 | US11274074, Example 10 [Chemical F...)
Affinity DataIC50: >1.00E+5nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM542067(US11274074, Example 12 [Chemical Formula 16])
Affinity DataIC50: >1.00E+5nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM542069(US11274074, Example 14 [Chemical Formula 18])
Affinity DataIC50: >1.00E+5nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50503448(CHEMBL4470594 | US11274074, Comparative Example 1 ...)
Affinity DataIC50: >1.00E+5nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50503435(CHEMBL4465797 | US11274074, Comparative Example 2 ...)
Affinity DataIC50: >1.00E+5nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50503436(CHEMBL4567262 | US11274074, Comparative Example 4 ...)
Affinity DataIC50: >1.00E+5nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50503438(CHEMBL4466337 | US11274074, Comparative Example 6 ...)
Affinity DataIC50: >1.00E+5nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50503451(CHEMBL4463597 | US11274074, Comparative Example 7 ...)
Affinity DataIC50: >1.00E+5nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM542081(US11274074, Comparative Example 12 [Chemical Formu...)
Affinity DataIC50: >1.00E+5nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM542084(US11274074, Comparative Example 15 [Chemical Formu...)
Affinity DataIC50: >1.00E+5nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50503452(CHEMBL4459865 | US11274074, Comparative Example 18...)
Affinity DataIC50: >1.00E+5nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50503433(CHEMBL4462374 | US11274074, Comparative Example 19...)
Affinity DataIC50: >1.00E+5nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50503439(CHEMBL4515829 | US11274074, Example 6 [Chemical Fo...)
Affinity DataIC50: >1.00E+5nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50503437(CHEMBL4516441 | US11274074, Example 4 [Chemical Fo...)
Affinity DataIC50: >1.00E+5nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50503434(CHEMBL4449467 | US11274074, Example 2 [Chemical Fo...)
Affinity DataIC50: >1.00E+5nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50239465(CHEMBL4080525 | US11274074, Control [Ani9])
Affinity DataIC50: >1.00E+5nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50503449(CHEMBL4517769 | US11274074, Example 10 [Chemical F...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of YFP-fused ANO2 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50503452(CHEMBL4459865 | US11274074, Comparative Example 18...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of YFP-fused ANO2 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50503448(CHEMBL4470594 | US11274074, Comparative Example 1 ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of YFP-fused ANO2 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50503442(CHEMBL4453660 | US11274074, Example 9 [Chemical Fo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of YFP-fused ANO2 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50503451(CHEMBL4463597 | US11274074, Comparative Example 7 ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of YFP-fused ANO2 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50239465(CHEMBL4080525 | US11274074, Control [Ani9])
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of YFP-fused ANO2 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50503441(CHEMBL4471557)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of YFP-fused ANO2 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50503439(CHEMBL4515829 | US11274074, Example 6 [Chemical Fo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of YFP-fused ANO2 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50503438(CHEMBL4466337 | US11274074, Comparative Example 6 ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of YFP-fused ANO2 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50503437(CHEMBL4516441 | US11274074, Example 4 [Chemical Fo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of YFP-fused ANO2 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50503436(CHEMBL4567262 | US11274074, Comparative Example 4 ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of YFP-fused ANO2 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50503435(CHEMBL4465797 | US11274074, Comparative Example 2 ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of YFP-fused ANO2 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50503434(CHEMBL4449467 | US11274074, Example 2 [Chemical Fo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of YFP-fused ANO2 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50503433(CHEMBL4462374 | US11274074, Comparative Example 19...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of YFP-fused ANO2 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed