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Found 12 of ic50 data for polymerid = 50003834,50006979
TargetDNA polymerase iota(Homo sapiens (Human))
University Of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM4078(6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0...)
Affinity DataIC50:  62nMAssay Description:Inhibition of human recombinant DNA polymerase iota expressed in Baculovirus expression system using TAMRA/BHQ-2-labeled primer/template measured at ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase iota(Homo sapiens (Human))
University Of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM60996(5-[(3-carboxy-4-hydroxy-phenyl)-(3-carboxy-4-keto-...)
Affinity DataIC50:  75nMAssay Description:Inhibition of human recombinant DNA polymerase iota expressed in Baculovirus expression system using TAMRA/BHQ-2-labeled primer/template measured at ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase iota(Homo sapiens (Human))
University Of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50318907(2-Ethoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of human DNA polymerase iota preincubated for 15 mins followed by replicating non-damaged DNA substrate addition measured after 30 mins in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase iota(Mus musculus)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50356642(CHEMBL1917196)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of C-terminal His6-tagged mouse DNA polymerase iota using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase iota(Mus musculus)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50356643(CHEMBL1917198)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of C-terminal His6-tagged mouse DNA polymerase iota using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase iota(Mus musculus)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50276865(4-[(2E)-but-2-enoyl]-2-[(1E,3E)-5-hydroxyhexa-1,3-...)
Affinity DataIC50:  1.98E+4nMAssay Description:Inhibition of mouse DNA polymerase iotaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase iota(Mus musculus)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50276936(4-(3-hydroxybutanoyl)-2-[(1E,3E)-5-hydroxyhexa-1,3...)
Affinity DataIC50:  3.25E+4nMAssay Description:Inhibition of mouse DNA polymerase iotaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase iota(Mus musculus)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50104668(CHEMBL3593571)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of C-terminal His6-tagged recombinant mouse DNA polymerase iota using poly(dA)/oligo(dT)18 and [3H]dTTP as template-primer and nucleotide ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase iota(Mus musculus)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50379292(CHEMBL2011646)
Affinity DataIC50:  5.02E+4nMAssay Description:Inhibition of mouse recombinant C-terminal-His6-tagged DNA polymerase iota assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase iota(Mus musculus)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50379293(CHEMBL2011648)
Affinity DataIC50:  6.38E+4nMAssay Description:Inhibition of mouse recombinant C-terminal-His6-tagged DNA polymerase iota assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase iota(Mus musculus)
Kyoto Prefectural University

Curated by ChEMBL
LigandPNGBDBM50379294(CHEMBL2011647)
Affinity DataIC50:  9.10E+4nMAssay Description:Inhibition of mouse recombinant C-terminal-His6-tagged DNA polymerase iota assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase iota(Homo sapiens (Human))
University Of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50428818(CHEMBL3142662)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human DNA polymerase iota using poly(dA)/oligo(dT)18 (A/T, 2/1)/dTTP DNA template-primer substrate measured at 37 degC for 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed