Compile Data Set for Download or QSAR
maximum 50k data
Found 41 of ic50 data for polymerid = 50006380
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50499822(CHEMBL3740897)
Affinity DataIC50:  83nMAssay Description:Inhibition of full length human PARP6 expressed in a Baculovirus infected Sf9 insect cells using activated DNA as substrate after 1 hr by streptavidi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50499821(CHEMBL3740104)
Affinity DataIC50:  640nMAssay Description:Inhibition of full length human PARP6 expressed in a Baculovirus infected Sf9 insect cells using activated DNA as substrate after 1 hr by streptavidi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of full length human PARP6 expressed in a Baculovirus infected Sf9 insect cells using activated DNA as substrate after 1 hr by streptavidi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553942(US11325906, Example 6)
Affinity DataIC50:  8.20E+3nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50505333(CHEMBL4437173)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length PARP6 expressed in Baculovirus infected Sf9 cells using biotinylated substrate afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50434157(CHEMBL2381958 | US9340549, 78)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PARP6 (unknown origin) using histone as substrate after 1 hr by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50318567(2-(4-(Trifluoromethyl)phenyl)-7,8-dihydro-5H-thiop...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PARP6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50434127(CHEMBL2381633)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PARP6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553969(US11325906, Example 32)
Affinity DataIC50:  1.00E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553967(US11325906, Example 30)
Affinity DataIC50:  1.00E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553948(US11325906, Example 12)
Affinity DataIC50:  1.10E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553951(US11325906, Example 14)
Affinity DataIC50:  1.10E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553939(US11325906, Example 3)
Affinity DataIC50:  1.40E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553966(US11325906, Example 29)
Affinity DataIC50:  1.40E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553938(US11325906, Example 2)
Affinity DataIC50:  1.40E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553959(US11325906, Example 22)
Affinity DataIC50:  1.60E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553944(US11325906, Example 8)
Affinity DataIC50:  1.80E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553940(US11325906, Example 4)
Affinity DataIC50:  1.90E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553947(US11325906, Example 11)
Affinity DataIC50:  2.20E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553943(US11325906, Example 7)
Affinity DataIC50:  2.20E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553941(US11325906, Example 5)
Affinity DataIC50:  2.30E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553946(US11325906, Example 10)
Affinity DataIC50:  2.60E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553968(US11325906, Example 31)
Affinity DataIC50:  2.80E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553955(US11325906, Example 18)
Affinity DataIC50: >2.90E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553956(US11325906, Example 19)
Affinity DataIC50: >2.90E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553950(US11325906, Example 13)
Affinity DataIC50:  3.00E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553953(US11325906, Example 16)
Affinity DataIC50:  3.10E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553958(US11325906, Example 21)
Affinity DataIC50:  3.30E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553937(US11325906, Example 1)
Affinity DataIC50:  3.40E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553945(US11325906, Example 9)
Affinity DataIC50:  4.70E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM431646(5-[[(2S)-1-(3-Oxo-3-[4-[5-(trifluoromethyl)pyrimid...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of PARP6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553954(US11325906, Example 17)
Affinity DataIC50:  5.90E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553952(US11325906, Example 15)
Affinity DataIC50:  8.00E+4nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553963(US11325906, Example 26)
Affinity DataIC50: >1.00E+5nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553964(US11325906, Example 27)
Affinity DataIC50: >1.00E+5nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553965(US11325906, Example 28)
Affinity DataIC50: >1.00E+5nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553961(US11325906, Example 24)
Affinity DataIC50: >1.00E+5nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553957(US11325906, Example 20)
Affinity DataIC50: >1.00E+5nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PARP-6 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553962(US11325906, Example 25)
Affinity DataIC50: >1.00E+5nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM553960(US11325906, Example 23)
Affinity DataIC50: >1.00E+5nMAssay Description:PARP6: Recombinant full length GST tagged PARP6 protein was diluted to 160 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent