Compile Data Set for Download or QSAR
maximum 50k data
Found 1845 of ic50 data for polymerid = 5468,50003106
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM142088(US11096924, DASH-inhibitors 2243 | US11559537, Com...)
Affinity DataIC50:  0.200nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50050516(Boronic acid derivative | CHEMBL63726 | US11096924...)
Affinity DataIC50:  0.200nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146987((S)-2-Amino-4-[(4-chloro-benzyl)-methyl-amino]-1-p...)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of human Dipeptidyl-peptidase II (DPP II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146972((S)-4-(4-chlorobenzylamino)-2-amino-1-(piperidin-1...)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of DPP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146971(2-(S)-Amino-4-(2-chloro-benzylamino)-1-piperidin-1...)
Affinity DataIC50:  0.230nMAssay Description:Inhibition of human Dipeptidyl-peptidase II (DPP II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146973(2-(S)-Amino-4-(2-benzyloxy-benzylamino)-1-piperidi...)
Affinity DataIC50:  0.390nMAssay Description:Inhibition of human Dipeptidyl-peptidase II (DPP II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146974((S)-2-Amino-4-(4-chloro-benzylamino)-1-(4-fluoro-p...)
Affinity DataIC50:  0.390nMAssay Description:Inhibition of human Dipeptidyl-peptidase II (DPP II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146952(2-(S)-Amino-4-(4-benzyloxy-benzylamino)-1-piperidi...)
Affinity DataIC50:  0.410nMAssay Description:Inhibition of human Dipeptidyl-peptidase II (DPP II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50196928((R)-1-((S)-2,4-diaminobutanamido)pentylboronic aci...)
Affinity DataIC50:  0.480nMAssay Description:Inhibition of human DPP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146972((S)-4-(4-chlorobenzylamino)-2-amino-1-(piperidin-1...)
Affinity DataIC50:  0.480nMAssay Description:Inhibition of DPP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146972((S)-4-(4-chlorobenzylamino)-2-amino-1-(piperidin-1...)
Affinity DataIC50:  0.480nMAssay Description:Inhibition of human Dipeptidyl-peptidase II (DPP II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50171546((S)-2,4-Diamino-N-((R)-1-boron-dihydroxide-pentyl)...)
Affinity DataIC50:  0.480nMAssay Description:Inhibitory concentration against human dipeptidylpeptidase 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146972((S)-4-(4-chlorobenzylamino)-2-amino-1-(piperidin-1...)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of DPP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146956((S)-2-Amino-4-(4-chloro-benzylamino)-1-(4-methyl-p...)
Affinity DataIC50:  0.550nMAssay Description:Inhibition of human Dipeptidyl-peptidase II (DPP II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146967((S)-2-Amino-4-dibenzylamino-1-piperidin-1-yl-butan...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human Dipeptidyl-peptidase II (DPP II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50191168((2S,4S)-4-(4-chlorobenzylamino)-2-amino-1-(piperid...)
Affinity DataIC50:  0.620nMAssay Description:Inhibition of DPP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146985((S)-2-Amino-4-(4-chloro-benzylamino)-1-(3-fluoro-p...)
Affinity DataIC50:  0.620nMAssay Description:Inhibition of human Dipeptidyl-peptidase II (DPP II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146977(2-(S)-Amino-4-(4-methoxy-benzylamino)-1-piperidin-...)
Affinity DataIC50:  0.660nMAssay Description:Inhibition of human Dipeptidyl-peptidase II (DPP II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50171555((S)-2,4-Diamino-1-(2-boron-dihydroxide-pyrrolidin-...)
Affinity DataIC50:  0.720nMAssay Description:Inhibitory concentration against human dipeptidylpeptidase 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146964(2-(S)-Amino-1-piperidin-1-yl-4-[(pyridin-4-ylmethy...)
Affinity DataIC50:  0.75nMAssay Description:Inhibition of human Dipeptidyl-peptidase II (DPP II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146957(2-(S)-Amino-1-piperidin-1-yl-4-[(thiophen-2-ylmeth...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human Dipeptidyl-peptidase II (DPP II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50050515(Boronic acid derivative | CHEMBL63652 | US11096924...)
Affinity DataIC50:  0.800nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50196929((S)-2,4-diamino-1-((3aR,6aR)-hexahydrocyclopenta[b...)
Affinity DataIC50:  0.880nMAssay Description:Inhibition of human DPP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146954(2-(S)-Amino-4-phenethylamino-1-piperidin-1-yl-buta...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human Dipeptidyl-peptidase II (DPP II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50050525((R)-1-((S)-2-aminopropanoyl)pyrrolidin-2-ylboronic...)
Affinity DataIC50:  1nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50171648(CHEMBL372180 | N-alkyl Gly-boro-Pro derivative)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against human DPP7 using Ala-Pro-AMC in fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50050528(Boronic acid derivative | CHEMBL63698 | US11096924...)
Affinity DataIC50:  1nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146991(2-(S)-Amino-4-[(naphthalen-2-ylmethyl)-amino]-1-pi...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human Dipeptidyl-peptidase II (DPP II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146968((S)-2-Amino-4-(4-chloro-benzylamino)-1-(3,6-dihydr...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human Dipeptidyl-peptidase II (DPP II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146955(2-(S)-Amino-4-(cyclohexylmethyl-amino)-1-piperidin...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human Dipeptidyl-peptidase II (DPP II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146950((S)-2-Amino-4-(4-chloro-benzylamino)-1-(3-methyl-p...)
Affinity DataIC50:  1.13nMAssay Description:Inhibition of human Dipeptidyl-peptidase II (DPP II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146960(2-(S)-Amino-4-[(naphthalen-1-ylmethyl)-amino]-1-pi...)
Affinity DataIC50:  1.31nMAssay Description:Inhibition of human Dipeptidyl-peptidase II (DPP II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146961(2-(S)-Amino-4-(3-chloro-benzylamino)-1-piperidin-1...)
Affinity DataIC50:  1.34nMAssay Description:Inhibition of human Dipeptidyl-peptidase II (DPP II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50050525((R)-1-((S)-2-aminopropanoyl)pyrrolidin-2-ylboronic...)
Affinity DataIC50:  1.40nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146988(CHEMBL440325 | N-((S)-3-Amino-4-oxo-4-piperidin-1-...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human Dipeptidyl-peptidase II (DPP II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146978((S)-2-Amino-4-phenylamino-1-piperidin-1-yl-butan-1...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human Dipeptidyl-peptidase II (DPP II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146953(2-(S)-Amino-4-(3-methoxy-benzylamino)-1-piperidin-...)
Affinity DataIC50:  1.77nMAssay Description:Inhibition of human Dipeptidyl-peptidase II (DPP II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146962(CHEMBL101401 | N-((S)-3-Amino-4-oxo-4-piperidin-1-...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human Dipeptidyl-peptidase II (DPP II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50171649(CHEMBL196933 | N-alkyl Gly-boro-Pro derivative)
Affinity DataIC50:  1.80nMAssay Description:Inhibitory activity against human DPP7 using Ala-Pro-AMC in fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146965(2-(S)-Amino-4-(3-phenyl-propylamino)-1-piperidin-1...)
Affinity DataIC50:  1.91nMAssay Description:Inhibition of human Dipeptidyl-peptidase II (DPP II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50171548((S)-2-(S)-Amino-1-(2-boron-dihydroxide-pyrrolidin-...)
Affinity DataIC50:  2nMAssay Description:Inhibitory concentration against human dipeptidylpeptidase 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146975(2-(S)-Amino-4-benzylamino-1-piperidin-1-yl-butan-1...)
Affinity DataIC50:  2.03nMAssay Description:Inhibition of human Dipeptidyl-peptidase II (DPP II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM142093(US11096924, DASH-inhibitors 1797 | US11559537, Com...)
Affinity DataIC50:  2.10nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50171645(2-Cyclodecylamino-1-pyrrolidin-1-yl--2-borandihydr...)
Affinity DataIC50:  2.20nMAssay Description:Inhibitory activity against human DPP7 using Ala-Pro-AMC in fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146979((S)-2-Amino-4-(4-chloro-benzylamino)-1-(2-methyl-p...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of human Dipeptidyl-peptidase II (DPP II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146969(3-[((S)-3-Amino-4-oxo-4-piperidin-1-yl-butylamino)...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of human Dipeptidyl-peptidase II (DPP II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50221977((2S,3S)-2-amino-3-(4'-fluoro-biphenyl-4-yl)-1-((S)...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50146981(2-(S)-Amino-4-(2,4-dimethoxy-benzylamino)-1-piperi...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of human Dipeptidyl-peptidase II (DPP II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50050527(Boronic acid derivative | CHEMBL66032 | US11096924...)
Affinity DataIC50:  2.90nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees Of Tufts College

US Patent
LigandPNGBDBM50191170((2S,4S)-4-(4-chlorobenzylamino)-2-amino-1-(piperid...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of DPP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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