Compile Data Set for Download or QSAR
maximum 50k data
Found 239 of ic50 data for polymerid = 5786,6565,7881
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50084952(4'-Carbamimidoyl-2'-methyl-biphenyl-4-carboxylic a...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition affinity against 5-HT-1B receptor in rat frontal cortex using radio binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50015711(3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1H-indole-5-ca...)
Affinity DataIC50:  0.800nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50084958(2'-Methyl-4'-(5-methyl-[1,3,4]oxadiazol-2-yl)-biph...)
Affinity DataIC50:  0.930nMAssay Description:Inhibition affinity against 5-HT-1B receptor in rat frontal cortex using radio binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50015714(3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1H-indol-5-ol ...)
Affinity DataIC50:  1.20nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50084953(2-Methyl-biphenyl-4,4'-dicarboxylic acid 4-amide 4...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition affinity against 5-HT-1B receptor in rat frontal cortex using radio binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM79215(CHEMBL15928 | GR 127935 | GR 127935 hydrochloride ...)
Affinity DataIC50:  1.60nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1B receptor in rat frontal cortex using [125I]-iodocyanopindolol as radio-ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM79215(CHEMBL15928 | GR 127935 | GR 127935 hydrochloride ...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition affinity against 5-HT-1B receptor in rat frontal cortex using radio binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50015712(5-Fluoro-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-in...)
Affinity DataIC50:  1.90nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM81498(5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50084959(11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...)
Affinity DataIC50:  2nMAssay Description:Inhibition affinity against 5-HT-1B receptor in rat frontal cortex using radio binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50086096(2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biph...)
Affinity DataIC50:  2.10nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1B receptor in rat frontal cortex using [125I]-iodocyanopindolol as radio-ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50015709(5-Bromo-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-ind...)
Affinity DataIC50:  3.20nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50015717(5-Chloro-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-in...)
Affinity DataIC50:  3.30nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50015718(5-Nitro-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-ind...)
Affinity DataIC50:  3.5nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM31023(3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | CHE...)
Affinity DataIC50:  3.70nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HT as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of radiolabeled [3H]-5-HT ligand binding to 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataIC50:  4.90nMAssay Description:Displacement of [125I]CYP from rat cerebral cortex 5HT1B receptor measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataIC50:  4.90nMAssay Description:Displacement of [125I]CYP from rat cerebral cortex 5-HT1B receptor in the presence of isoproternolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HT as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50084961(2'-Methyl-4'-(5-methyl-[1,3,4]oxadiazol-2-yl)-biph...)
Affinity DataIC50:  6.30nMAssay Description:Inhibition affinity against 5-HT-1B receptor in rat frontal cortex using radio binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50084960(2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biph...)
Affinity DataIC50:  7.30nMAssay Description:Inhibition affinity against 5-HT-1B receptor in rat frontal cortex using radio binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50084951(2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biph...)
Affinity DataIC50:  10nMAssay Description:Inhibition affinity against 5-HT-1B receptor in rat frontal cortex using radio binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50407769(CHEMBL301765)
Affinity DataIC50:  13.8nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1B receptor was measured using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50407769(CHEMBL301765)
Affinity DataIC50:  13.8nMAssay Description:Binding affinity for 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM392076(US10301272, Example 7/9)
Affinity DataIC50:  14nMAssay Description:Displacement of [125I]-CYP from rat brain 5-HT1B receptor after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM84737(3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1,4-dihydro-py...)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50064587(6-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataIC50:  20nMAssay Description:Affinity towards 5-hydroxytryptamine 1B receptor in membranes from rat frontal cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50015710(4-Piperazin-1-yl-7-trifluoromethyl-pyrrolo[1,2-a]q...)
Affinity DataIC50:  21nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50086115(5-[4-(5-fluoro-1H-3-indolyl)hexahydro-1-pyridinylc...)
Affinity DataIC50:  23nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1B receptor in rat frontal cortex using [125I]-iodocyanopindolol as radio-ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50007406(1-(3-(trifluoromethyl)phenyl)piperazine | 1-(3-Tri...)
Affinity DataIC50:  27nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50064582(6-{2-[4-(2-Hydroxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataIC50:  31nMAssay Description:Affinity towards 5-hydroxytryptamine 1B receptor in membranes from rat frontal cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50086099(4-(4-Fluoro-1H-indol-3-yl)-piperidine-1-carboxylic...)
Affinity DataIC50:  50nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1B receptor in rat frontal cortex using [125I]-iodocyanopindolol as radio-ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50086111(4-(1H-Indol-3-yl)-piperidine-1-carboxylic acid [4-...)
Affinity DataIC50:  50nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1B receptor in rat frontal cortex using [125I]-iodocyanopindolol as radio-ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50007406(1-(3-(trifluoromethyl)phenyl)piperazine | 1-(3-Tri...)
Affinity DataIC50:  51nMAssay Description:Concentration of the compound necessary to achieve half maximal inhibition of [125I]- Iodocyanopindolol binding to 5-hydroxytryptamine 1B receptor at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50084955(2'-Methyl-4'-(5-methyl-[1,3,4]oxadiazol-2-yl)-biph...)
Affinity DataIC50:  60nMAssay Description:Inhibition affinity against 5-HT-1B receptor in rat frontal cortex using radio binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50064580(6-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}...)
Affinity DataIC50:  61nMAssay Description:Affinity towards 5-hydroxytryptamine 1B receptor in membranes from rat frontal cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50086097(1-[2-(5-Fluoro-1H-indol-3-yl)-ethyl]-3-[4-methoxy-...)
Affinity DataIC50:  63nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1B receptor in rat frontal cortex using [125I]-iodocyanopindolol as radio-ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50064586(3-Methyl-6-{2-[4-(3-trifluoromethyl-phenyl)-pipera...)
Affinity DataIC50:  70nMAssay Description:Affinity towards 5-hydroxytryptamine 1B receptor in membranes from rat frontal cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50084954(CHEMBL443762 | Methanesulfonic acid 4-{[2'-methyl-...)
Affinity DataIC50:  70nMAssay Description:Inhibition affinity against 5-HT-1B receptor in rat frontal cortex using radio binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50086101(4-[4-(5-Fluoro-1H-indol-3-yl)-butyl]-piperazine-1-...)
Affinity DataIC50:  77nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1B receptor in rat frontal cortex using [125I]-iodocyanopindolol as radio-ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50086112(4-(6-Fluoro-1H-indol-3-yl)-piperidine-1-carboxylic...)
Affinity DataIC50:  80nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1B receptor in rat frontal cortex using [125I]-iodocyanopindolol as radio-ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50060684(9-Fluoro-4-piperazin-1-yl-pyrrolo[1,2-a]quinoxalin...)
Affinity DataIC50:  106nMAssay Description:Inhibition of radiolabeled [3H]-5-HT ligand binding to 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataIC50:  110nMAssay Description:5-HT1D binding assays (agonist radioligand)were performed using bovine caudate membranes according to the methods of Heuring and Peroutka (J. Neurosc...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50086095(3-{1-[4-Methoxy-3-(4-methyl-piperazin-1-yl)-phenyl...)
Affinity DataIC50:  113nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1B receptor in rat frontal cortex using [125I]-iodocyanopindolol as radio-ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50086104(4-[2-(1H-Indol-3-yl)-ethyl]-piperidine-1-carboxyli...)
Affinity DataIC50:  120nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1B receptor in rat frontal cortex using [125I]-iodocyanopindolol as radio-ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50086106(1-[3-(2-Dimethylamino-ethoxy)-4-methoxy-phenyl]-3-...)
Affinity DataIC50:  133nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1B receptor in rat frontal cortex using [125I]-iodocyanopindolol as radio-ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM81497(4-(4-Methyl-piperazin-1-yl)-7-trifluoromethyl-pyrr...)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50408171(CHEMBL53490)
Affinity DataIC50:  151nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1B receptor was measured using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM106698(CHEMBL1957349 | US8586620, 42)
Affinity DataIC50:  160nMAssay Description:5-HT1D binding assays (agonist radioligand)were performed using bovine caudate membranes according to the methods of Heuring and Peroutka (J. Neurosc...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50060679(7-Fluoro-4-piperazin-1-yl-pyrrolo[1,2-a]quinoxalin...)
Affinity DataIC50:  167nMAssay Description:Inhibition of radiolabeled [3H]-5-HT ligand binding to 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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