Compile Data Set for Download or QSAR
maximum 50k data
Found 36 of ic50 data for polymerid = 5886
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataIC50: <1nMAssay Description:Inhibition of Bcl-wMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM333146(Compound I | US10196404, Example 1 | US10196404, E...)
Affinity DataIC50: >20nMAssay Description:Inhibition of N-terminal His6-tagged Bcl-w (1 to 171 residues) (unknown origin) expressed in Escherichia coli using biotin-labeled Bim peptide GGMRPE...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataIC50:  40nMAssay Description:Displacement of wild type mBimBH3 from human Bcl-w by solution competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataIC50:  66nMpH: 7.4Assay Description:The protocols for tight and weak binders were described in Biacore S51 assay set-up with a flow rate of 30 µL/min. For His-Bcl-2 protein assays...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataIC50:  66nMAssay Description:Binding affinity to Bcl-w (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50270877((R)-4-(4-((2-(4-chlorophenyl)-5,5-dimethylcyclohex...)
Affinity DataIC50:  70nMAssay Description:Inhibition of recombinant human N-terminal 6xHis-tagged Bcl-w (M1 to R171) expressed in Escherichia coli using HyLite Fluor 647-labeled Bim peptide a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50339779(CHEMBL1689141 | N-{7-[4-(4'-Chloro-biphenyl-2-ylme...)
Affinity DataIC50:  245nMAssay Description:Displacement of wild type mBimBH3 from human Bcl-w by solution competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50339783(CHEMBL1689145 | N-(7-{4-[2-(4-Chloro-phenyl)-5,5-d...)
Affinity DataIC50:  275nMAssay Description:Displacement of wild type mBimBH3 from human Bcl-w by solution competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50339777((R)-N-(7-(4-((4'-chlorobiphenyl-2-yl)methyl)pipera...)
Affinity DataIC50:  440nMAssay Description:Displacement of wild type mBimBH3 from human Bcl-w by solution competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50339781(CHEMBL1689143 | N-(7-{4-[2-(4-Chloro-phenyl)-5,5-d...)
Affinity DataIC50:  540nMAssay Description:Displacement of wild type mBimBH3 from human Bcl-w by solution competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50529037(CHEMBL4592905)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of recombinant human N-terminal 6xHis-tagged Bcl-w (M1 to R171) expressed in Escherichia coli using HyLite Fluor 647-labeled Bim peptide a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50339776(CHEMBL1689146 | N-(7-{4-[2-(4-Chloro-phenyl)-5,5-d...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of wild type mBimBH3 from human Bcl-w by solution competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50339782(CHEMBL1689144 | N-(7-{4-[2-(4-Chloro-phenyl)-5,5-d...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of wild type mBimBH3 from human Bcl-w by solution competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50339780(CHEMBL1689142 | N-{7-[4-(4'-Chloro-biphenyl-2-ylme...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of wild type mBimBH3 from human Bcl-w by solution competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50339778(CHEMBL1689140 | N-{7-[4-(4'-Chloro-biphenyl-2-ylme...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of wild type mBimBH3 from human Bcl-w by solution competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50529042(CHEMBL4473013)
Affinity DataIC50:  4.01E+3nMAssay Description:Inhibition of recombinant human N-terminal 6xHis-tagged Bcl-w (M1 to R171) expressed in Escherichia coli using HyLite Fluor 647-labeled Bim peptide a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM109236(WEHI-539)
Affinity DataIC50:  4.10E+3nM Kd: >550nMpH: 7.4Assay Description:The protocols for tight and weak binders were described in Biacore S51 assay set-up with a flow rate of 30 µL/min. For His-Bcl-2 protein assays...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50529035(CHEMBL4474764)
Affinity DataIC50:  4.37E+3nMAssay Description:Inhibition of recombinant human N-terminal 6xHis-tagged Bcl-w (M1 to R171) expressed in Escherichia coli using HyLite Fluor 647-labeled Bim peptide a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM109233(2-(8-(2-(Benzothiazol-2-yl)hydrazono)-5,6,7,8-tetr...)
Affinity DataIC50:  5.00E+3nMAssay Description:Binding affinity to Bcl-w (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50436628(CHEMBL2398263)
Affinity DataIC50:  5.00E+3nMAssay Description:Binding affinity to Bcl-w (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM109233(2-(8-(2-(Benzothiazol-2-yl)hydrazono)-5,6,7,8-tetr...)
Affinity DataIC50:  5.30E+3nMpH: 7.4Assay Description:The protocols for tight and weak binders were described in Biacore S51 assay set-up with a flow rate of 30 µL/min. For His-Bcl-2 protein assays...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50181019(1-(2-methoxyphenethyl)-5-butyl-4-(2-phenoxyphenyl)...)
Affinity DataIC50:  8.09E+3nMAssay Description:Inhibition of Bclw by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50436643(3-(5-(1-(2-(Benzo[d]thiazol-2-yl)hydrazono)ethyl)f...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to Bcl-w (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50436646(CHEMBL2398249)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to Bcl-w (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50436645(CHEMBL2398262)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to Bcl-w (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM109232(6-(8-(2-(Benzothiazol-2-yl)hydrazono)-5,6,7,8-tetr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to Bcl-w (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM109232(6-(8-(2-(Benzothiazol-2-yl)hydrazono)-5,6,7,8-tetr...)
Affinity DataIC50: >1.00E+4nMpH: 7.4Assay Description:The protocols for tight and weak binders were described in Biacore S51 assay set-up with a flow rate of 30 µL/min. For His-Bcl-2 protein assays...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50436648(CHEMBL2398286)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to Bcl-w (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50436626(CHEMBL2398170)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to Bcl-w (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50529034(CHEMBL4584015)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibition of recombinant human N-terminal 6xHis-tagged Bcl-w (M1 to R171) expressed in Escherichia coli using HyLite Fluor 647-labeled Bim peptide a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50181020(1-(2-methoxybenzyl)-4-(2-phenoxyphenyl)-5-propyl-1...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of Bclw by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50529040(CHEMBL4529727)
Affinity DataIC50:  1.45E+4nMAssay Description:Inhibition of recombinant human N-terminal 6xHis-tagged Bcl-w (M1 to R171) expressed in Escherichia coli using HyLite Fluor 647-labeled Bim peptide a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50529036(CHEMBL4560892)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of recombinant human N-terminal 6xHis-tagged Bcl-w (M1 to R171) expressed in Escherichia coli using HyLite Fluor 647-labeled Bim peptide a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50181021(1-biphenyl-3-ylmethyl-5-butyl-4-(2-methoxy-phenyl)...)
Affinity DataIC50:  2.69E+4nMAssay Description:Inhibition of Bclw by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50436627(CHEMBL2398290)
Affinity DataIC50: >3.30E+4nMAssay Description:Binding affinity to Bcl-w (unknown origin) by luminescence proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50529039(CHEMBL4446373)
Affinity DataIC50:  5.91E+4nMAssay Description:Inhibition of recombinant human N-terminal 6xHis-tagged Bcl-w (M1 to R171) expressed in Escherichia coli using HyLite Fluor 647-labeled Bim peptide a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed